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Risk for melanoma could be estimated by DNA mutation count

Risk for melanoma, the most deadly skin cancer, can be estimated long before detection of any suspicious moles, according to a UC San Francisco scientist who led a new study to detect DNA mutations in individual skin cells.

8 Oct 2020

CAR T cell therapy can predict treatment outcomes in patients with large B-cell lymphoma

Scientists have identified cellular and molecular features of anti-CD19 CAR T cell infusion products that are correlated with large B-cell lymphoma (LBCL).

6 Oct 2020

Researchers identify gene related to seed dispersal in green millet

For years, Elizabeth (Toby) Kellogg, PhD, member and Robert E. King Distinguished Investigator and other researchers at the Donald Danforth Plant Science Center (Danforth Center) drove up and down the highways of the continental United States, occasionally pulling over to the side of the road to collect small weedy plants and bring them back to the lab.

6 Oct 2020

Cancer mutations occur in distinct patterns based on 3D structure of the genome

A new study from researchers at The University of Texas MD Anderson Cancer Center has discovered that mutations found in cancers do not accumulate randomly, but are found in distinct patterns that vary based on the three-dimensional organization of the genome in the cell as well as the underlying factors causing the mutations.

6 Oct 2020

Study shows patients can benefit from personalized cancer therapy

Scientists have shown that patients, who are receiving care for cancer, have a greater chance of surviving if they received personalized cancer treatment.

From UC San Diego 5 Oct 2020

Type and direction of force on a cell can alter gene expression

Tissues and cells in the human body are subjected to a constant push and pull - strained by other cells, blood pressure and fluid flow, to name a few.

5 Oct 2020

Researchers map genetic networks controlling human regulatory T cell identity

Unlike most T cells, which launch immune responses against foreign molecules, regulatory T cells are the peacekeepers of the human immune system, damping down inflammatory reactions when they're not needed.

5 Oct 2020

Genetic test identifies patients with invasive lobular carcinoma at high risk of recurrence

New results to be presented at the 12th European Breast Cancer Conference show that a test, which looks at the activity of 70 genes in breast cancer tissue, is possible to use in the clinic to identify patients with invasive lobular carcinoma (ILC) that is at high risk of recurring and progressing.

1 Oct 2020

New mobile app analyzes SARS-CoV-2 genome on a smartphone

A new mobile app has made it possible to analyse the genome of the SARS-CoV-2 virus on a smartphone in less than half an hour.

30 Sep 2020

Study sheds new light on the role of Y chromosome genes

Scientists have a shed new light on a little-known role of Y chromosome genes, which are specific to men.

25 Sep 2020

Genetic variations may not contribute to mortality and morbidity of COVID-19

Researchers did not find any major differences across populations and ethnic groups in seven genes linked to the viral entry of SARS-CoV-2.

25 Sep 2020

Researchers discover how antibiotic resistance genes spread via plasmids

For the first time, researchers have discovered how antibiotic resistance genes are spreading, at a continental scale, via bacterial plasmids in the hospital superbug, Klebsiella pneumoniae.

25 Sep 2020

Researchers discover novel genes for human deafness in Israeli families

Until now, seven genes were known to be involved in hearing loss in Israel's Jewish population. A new study led by Zippora Brownstein, PhD, and Prof. Karen Avraham from the Sackler Faculty of Medicine at Tel Aviv University has found that 32 genes are responsible for inherited hearing loss in Israeli Jewish families.

24 Sep 2020

ADHD study reveals genetic differences between African Americans and people of European ancestry

Researchers from Children's Hospital of Philadelphia (CHOP) have shown there may be key genetic differences in the causes of attention-deficit hyperactivity disorder (ADHD) between African Americans and people of European ancestry, which may play an important part in how patients of different ethnic backgrounds respond to treatments for this condition. The findings were published online by the journal Scientific Reports.

23 Sep 2020