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Experts identify novel mechanisms involved in macrophage polarization

Macrophages are important cells of the immune system with numerous beneficial functions. However, macrophages also aggravate common diseases.

8 Nov 2021

Brown fat protects against secondary obesity-related diseases, says study

Research demonstrated that obese individuals with active brown fat possess a healthier metabolism and utilize more energy than obese people without.

8 Nov 2021

Research reveals pathways controlling osteocyte development

Osteocytes are seen within bone tissue. They are cells with tree-like projections known as dendrites vital for receiving communication from other cells.

4 Nov 2021

Research uncovers key component of cellular malfunction that contributes to tumor growth

Scientists have homed in on a crucial step within the sequence of chemical reactions that govern regulation of cell division, proliferation and death, and whose malfunction contributes to the growth of tumors.

3 Nov 2021

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia.

3 Nov 2021

Study reveals a link between prenatal PFAS exposure and late-onset preeclampsia

Perfluoroalkyl substances (PFAS), sometimes referred to as "forever chemicals," are long-lasting, man-made substances known to pollute the drinking water supplies of many communities.

2 Nov 2021

Key networks controlling pluripotency and apoptosis during development revealed

During the early stages of human embryonic development, a small collection of cells called human embryonic stem cells co-ordinates growth and differentiation finally giving rise to highly specialized human tissues.

1 Nov 2021

Study: Forgotten antibiotic led to lower selection of resistant bacteria

A forgotten antibiotic, temocillin, led to lower selection of resistant bacteria than the standard treatment for febrile urinary tract infection, in a study published in The Lancet Infectious Diseases.

29 Oct 2021

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

29 Oct 2021

New eToeholds could make RNA therapeutics more safer and effective

RNAs are best known as the molecules that translate information encoded in genes into proteins with their myriad of activities.

29 Oct 2021

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Cleveland Clinic researchers have shown for the first time that diet-associated molecules in the gut are associated with aggressive prostate cancer, suggesting dietary interventions may help reduce risk. Findings from the study were published in Cancer Epidemiology, Biomarkers & Prevention.

29 Oct 2021

Novel genetic biomarkers accurately predict SARS-CoV-2 infection, says study

Researchers from the University of Colorado School of Medicine identified specific genetic biomarkers that reveal who is infected with COVID-19.

29 Oct 2021

Nonpathogenic strain of C. acnes improves skin's resistance against infection-causing bacteria

Cutibacterium acnes, a bacteria that is known to cause acne, is also widely spread on people with healthy skin.

28 Oct 2021

Intussusceptive angiogenesis contributes to growth of daughter tumors in malignant melanoma

For the first time, researchers at the University of Gothenburg have shown that metastases in patients with malignant melanoma gain access to the circulatory system not only through the outgrowth of new blood vessel branches, but also an alternative process in which one blood vessel divide into two parallel vessels bylongitudinal splitting.

28 Oct 2021

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Parkinson's disease (PD) is the most common neurodegenerative movement disorder, afflicting more than 10 million people worldwide and more than one million Americans. While there is no cure for PD, current therapies focus on treating motor symptoms and fail to reverse, or even address, the underlying neurological damage.

26 Oct 2021

Genetic biomarker test could help personalize therapy for men with high-risk prostate cancer

A new meta-analysis finds that a genetic biomarker test accurately predicts how men with high-risk prostate cancer will respond to treatment with radiation and hormone therapy.

26 Oct 2021

Cell-free DNA employed to identify measurable residual disease

Researchers demonstrated that cell-free DNA from CSF could be employed to examine MRD in children treated for the brain tumor medulloblastoma.

25 Oct 2021

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

As scientists have probed the mysteries of life down to smaller and smaller scales, they have invented tools to help them understand what they observe.

22 Oct 2021

Research opens new therapeutic perspectives for treatment of skin fibrosis

Collagen, the main component of the skin's extracellular matrix, can cause a pathological condition if it is in excess. Applying an electric field to the skin affects collagen pathways, temporarily reducing collagen production and increasing its degradation.

22 Oct 2021

Targeted drug shows promise against brain metastases from kidney cancer

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need.

22 Oct 2021

Hospital News and Research

Experts identify novel mechanisms involved in macrophage polarization

Brown fat protects against secondary obesity-related diseases, says study

Research reveals pathways controlling osteocyte development

Research uncovers key component of cellular malfunction that contributes to tumor growth

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Study reveals a link between prenatal PFAS exposure and late-onset preeclampsia

Key networks controlling pluripotency and apoptosis during development revealed

Study: Forgotten antibiotic led to lower selection of resistant bacteria

Immune cell patterns can help predict kidney cancer patients' response to immunotherapy

New eToeholds could make RNA therapeutics more safer and effective

Diet-associated molecules in the gut are linked with aggressive prostate cancer

Novel genetic biomarkers accurately predict SARS-CoV-2 infection, says study

Nonpathogenic strain of C. acnes improves skin's resistance against infection-causing bacteria

Intussusceptive angiogenesis contributes to growth of daughter tumors in malignant melanoma

Study identifies a novel role for regulatory protein Bach1 in Parkinson's disease

Genetic biomarker test could help personalize therapy for men with high-risk prostate cancer

Cell-free DNA employed to identify measurable residual disease

Scientists use DNA to create what may be the world's tiniest ruler for measuring proteins

Research opens new therapeutic perspectives for treatment of skin fibrosis

Targeted drug shows promise against brain metastases from kidney cancer

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