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Researchers Discover Genes Key to Spitting Cobra Venom's Cytotoxicity

Functional genomics to dissect and understand the cytotoxicity of spitting cobra venom and define the genetic interactions between the venom and the target to develop a locally acting antidote.

25 Jul 2024

Traffic-Related Ultrafine Particles Cause Mitochondrial Dysfunction in Olfactory Mucosa

Ultrafine particles, UFPs, the smallest contributors to air pollution, hinder the function of mitochondria in human olfactory mucosa cells, a new study shows.

25 Jul 2024

NanoRanger Offers Rapid, Precise Diagnosis for Genetic Diseases

An effective long-read sequencing method that looks for intricate genomic variations can quickly and accurately diagnose genetic disorders molecularly.

24 Jul 2024

Harnessing Enzymes for Making RNA Therapeutics

While the COVID-19 vaccines introduced many people to RNA-based medicines, RNA oligonucleotides have already been on the market for years to treat diseases like Duchenne Muscular Dystrophy and amyloidosis.

15 Jul 2024

Macrophage Inflammation may Contribute to LSD Symptoms

Researchers at The Hospital for Sick Children (SickKids) have found that inflammation in an immune cell may be responsible in part for some severe symptoms in a group of rare genetic conditions called lysosomal storage diseases (LSDs).

15 Jul 2024

New Insights into ILC2 Development Could Lead to Innovative Therapies for Allergic Diseases

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Exploring Gut Microbiome Modulation for Disease Prevention

Carriers of gut Blastocystis, a single-celled organism that has been classified as either a parasite or harmless organism but is frequently found in the digestive system, were associated with markers of good cardiovascular health and decreased body fat in an analysis of over 50,000 people from around the world.

9 Jul 2024

TRPC5 Gene Alterations: A Key Player in Obesity and Postpartum Depression

Researchers at Baylor College of Medicine, the University of Cambridge and collaborating institutions have discovered that alterations in the human gene TRPC5 cause obesity and postpartum depression.

3 Jul 2024

Time-Driven Dynamics of Gut Microbiota: Implications for Disease Research

Our bodies are inhabited by trillions of microorganisms, with specific microbes unique to each individual.

2 Jul 2024

Enzymatic Breakdown of Bacterial Cell Wall Facilitates Antibiotic Resistance Gene Transfer

A study at Umeå University, Sweden, provides new clues in the understanding of how antibiotic resistance spreads.

2 Jul 2024

Mice Studies Shed Light on Serotonin and Memory

Memory regulation in humans and animal models is regulated by the serotonin 2C receptor in the brain, according to research from Baylor College of Medicine, the University of Cambridge in the United Kingdom, and affiliated institutions.

1 Jul 2024

Study Uncovers a Biological Explanation for Long-Term Memories

Whether it's a first-time visit to a zoo or when we learned to ride a bicycle, we have memories from our childhoods kept well into adult years.

27 Jun 2024

Christchurch Variant Offers Protection Against Early-Onset Alzheimer's

A scientific story that began with a discovery in just one extraordinary patient is now panning out.

21 Jun 2024

St. Jude Researchers Discover NLRC5's Role in Inflammatory Cell Death

The innate immune system is responsible for protecting the human body from threats that could cause disease or infection.

17 Jun 2024

TIMP-1 Protein Enhances Immune Defense Against Cancer

Researchers at the University of Turku in Finland have found a new function for an existing protein.

17 Jun 2024

New Method Offers Rapid and Accurate Blood Infection Detection

Researchers have shown that a novel method could identify bloodstream infections precisely and swiftly. The study findings were presented at ASM Microbe, the annual meeting of the American Society for Microbiology.

17 Jun 2024

Columbia Studies Uncover Misidentification of Gut Stem Cells

Two independent studies by Columbia scientists suggest that research into the gut's stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.

7 Jun 2024

Novel Lipopeptide from Serratia marcescens Shows Promise Against Staphylococcus aureus Infections

A novel antibacterial lipopeptide produced by the bacterium Serratia marcescens has been shown to be highly effective in killing Staphylococcus aureus – one of the most important pathogens occurring in humans.

7 Jun 2024

Researchers Advance Single-Molecule DNA Sequencing Techniques

In recent years, technologies that allow scientists to investigate a person's DNA at single-molecule resolution have greatly increased the knowledge of the human genome, microbiome, and the genetic basis of disease.

5 Jun 2024