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New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

A research team led by Dr Aixin YAN, Associate Professor from the Research Division for Molecular & Cell Biology, Faculty of Science, in collaboration with Honorary Clinical Professor Patrick CY WOO from the Department of Microbiology, Li Ka Shing Faculty of Medicine, the University of Hong Kong, reported the development of a transferrable and integrative type I CRISPR-based platform.

23 Jul 2021

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

SARS-CoV-2 is still a major threat to humankind. The constant emergence of variants makes the threat made by the virus difficult to estimate. The SARS-CoV-2 variant B.1.617 spread in India and gave rise to the Delta variant, B.1.617.2, which is now dominant in numerous countries.

23 Jul 2021

SARS-CoV-2 variant B.1.617 can infect lung and intestinal cells more efficiently than the original virus

SARS-CoV-2 still poses major challenges to mankind. The frequent emergence of mutant forms makes the threat posed by the virus difficult to predict.

22 Jul 2021

Study finds no evidence that caffeine consumption leads to greater risk of arrhythmias

In the largest study of its kind, an investigation by UC San Francisco has found no evidence that moderate coffee consumption can cause cardiac arrhythmia.

21 Jul 2021

Study holds phages responsible for superbug emergence

Scientists unraveled that phages are responsible for the initiation of rapid bacterial evolution that leads to the rise of treatment-resistant “superbugs.”

21 Jul 2021

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Lymph nodes are critical to the body's immune response against tumors but paradoxically, cancer cells that spread, or metastasize, to lymph nodes can often avoid being eliminated by immune cells.

20 Jul 2021

Study confirms long-term immune system responses of adenovirus vaccines for COVID-19

Researchers from the University of Oxford suggest that adenovirus vaccine vectors may create strong long-term immune system responses.

19 Jul 2021

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Single-cell RNA sequencing has revealed a subset of cells that could provide protection from a rare, but severely debilitating and fatal, lung disease.

16 Jul 2021

Brainless slime mold uses its body to sense mechanical cues in the environment

If you didn't have a brain, could you still figure out where you were and navigate your surroundings? Thanks to new research on slime molds, the answer may be "yes."

15 Jul 2021

Mass spectrometry: Important analytical tool to understand Huntington’s disease proteome

Mass spectrometry has emerged as an important analytical tool for gaining a better understanding of mechanisms underlying Huntington's disease (HD), alongside the increased availability of cell and animal models of the disease.

14 Jul 2021

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Newly devised gene therapy can help children born with AADC, a rare genetic disorder that causes developmental and physical disabilities.

13 Jul 2021

Liver fibrosis might be treatable with selective immunotoxins

Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

13 Jul 2021

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Children with a devastating genetic disorder characterized by severe motor disability and developmental delay have experienced sometimes dramatic improvements in a gene therapy trial launched at UCSF Benioff Children's Hospitals.

13 Jul 2021

Study reveals how fine-tuning the immune system can improve vaccines, reduce disease severity

Immunologists have discovered a molecular route that regulates how crucial immune cells evolve into the immune system’s functioning components.

9 Jul 2021

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Scientists discovered 22 lipids in the blood plasma of schizophrenia patients that were linked to slower symptom improvement over time.

8 Jul 2021

Researchers analyze and describe immune cells in the human bile duct

The immune cells that reside in the human bile duct have been studied and described in depth by researchers at Karolinska Institutet.

25 Jun 2021

Kirigami-inspired stent could deliver drugs to tubular organs

Inspired by kirigami, the Japanese art of folding and cutting paper to create three-dimensional structures, MIT engineers and their collaborators have designed a new type of stent that could be used to deliver drugs to the gastrointestinal tract, respiratory tract, or other tubular organs in the body.

15 Jun 2021

New research focuses on possible treatment options for childhood brain cancer

Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.

11 Jun 2021

SARS-CoV-2 virus does not spread on hospital surfaces

By observing what was going on across the world in early 2020, researchers from the University of California San Diego School of Medicine knew that their region will soon be flooded with patients infected with COVID-19—the disease caused by the coronavirus, SARS-CoV-2.

11 Jun 2021

Consuming large amounts of daily caffeine may increase the risk of glaucoma

Consuming large amounts of daily caffeine may increase the risk of glaucoma more than three-fold for those with a genetic predisposition to higher eye pressure according to an international, multi-center study.

8 Jun 2021

Hospital News and Research

New transferrable and integrative type I CRISPR-based platform to efficiently edit superbugs

Study reveals SARS-CoV-2 variant is less sensitive to inhibition by antibodies

SARS-CoV-2 variant B.1.617 can infect lung and intestinal cells more efficiently than the original virus

Study finds no evidence that caffeine consumption leads to greater risk of arrhythmias

Study holds phages responsible for superbug emergence

Scientists provide insights on immune evasion of metastatic cancer cells in lymph nodes

Study confirms long-term immune system responses of adenovirus vaccines for COVID-19

Specific subset of fibroblast cells could provide protection from debilitating lung disease

Brainless slime mold uses its body to sense mechanical cues in the environment

Mass spectrometry: Important analytical tool to understand Huntington’s disease proteome

Novel gene therapy offers hope to children with genetic, neurodegenerative diseases

Liver fibrosis might be treatable with selective immunotoxins

Children with rare genetic disorder experience dramatic improvements in a gene therapy trial

Study reveals how fine-tuning the immune system can improve vaccines, reduce disease severity

Lipidomics study reveals schizophrenic patients’ resistance to antipsychotic drugs

Researchers analyze and describe immune cells in the human bile duct

Kirigami-inspired stent could deliver drugs to tubular organs

New research focuses on possible treatment options for childhood brain cancer

SARS-CoV-2 virus does not spread on hospital surfaces

Consuming large amounts of daily caffeine may increase the risk of glaucoma

Carrying out CRISPR/Cas9 in Space

Raising your risk of cardiac death through the Southern Diet

Determining class A drug use from a single fingerprint

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