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Increased blood lead levels in children are linked to reduced expression of genes

Researchers have revealed a connection between methylation of genes implicated in heme synthesis and carcinogenesis and high blood lead levels in children, signifying a previously unfamiliar mechanism for lead poisoning.

10 Aug 2020

Researchers discover genetic cause of severe auto inflammatory syndrome

Researchers from the Icahn School of Medicine used a novel genetic sequencing technology to identify the genetic cause of--and a treatment for--a previously unknown severe auto inflam-matory syndrome affecting an 18-year-old girl since infancy.

5 Aug 2020

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Scientists at UCL have discovered new biomarkers, which may identify those people with Type 1 diabetes who would benefit from the immunotherapy drug Abatacept, a finding which could eventually help thousands manage the disease more effectively.

From University College London 4 Aug 2020

Detecting rare circulating tumor cells

Metastasis - the development of tumor growth at a secondary site - is responsible for the majority of cancer-related deaths.

4 Aug 2020

A new cell-based gene therapy approach to correct hemophilia A

In a new study from the Wake Forest Institute for Regenerative Medicine (WFIRM) researchers have developed an optimized cellular platform for delivering Factor 8 to better treat patients with hemophilia A.

29 Jul 2020

Coronavirus changes structure that prevents cells from detecting it

With an alarm code, we can enter a building without bells going off. It turns out that the SARS coronavirus 2 (SARS-CoV-2) has the same advantage entering cells. It possesses the code to waltz right in.

24 Jul 2020

Study shows how cancer develops resistance to chemotherapy

Cancer's knack for developing resistance to chemotherapy has long been a major obstacle to achieving lasting remissions or cures. While tumors may shrink soon after chemotherapy, many times they eventually grow back.

24 Jul 2020

Genes and cardiovascular health contribute to a person's dementia risk

Genes and cardiovascular health each contribute in an additive way to a person's risk of dementia, U.S. researchers including Sudha Seshadri, MD, and Claudia Satizabal, PhD, of The University of Texas Health Science Center at San Antonio (UT Health San Antonio) reported July 20 in the journal Neurology.

21 Jul 2020

Small, compact Cas proteins found in bacteriophages are ideal for gene editing

The DNA-cutting proteins central to CRISPR-Cas9 and related gene-editing tools originally came from bacteria, but a newfound variety of Cas proteins apparently evolved in viruses that infect bacteria.

20 Jul 2020

Substances that target oxytocin receptors can help treat various diseases

Oxytocin is the so-called “cuddle hormone” or “love hormone” that plays a role in strengthening the relationship between the mother and child and controlling social bonding.

17 Jul 2020

Stem cell treatment could improve the quality of donor kidneys

New research has demonstrated that kidneys can be revived prior to transplantation by delivering a cell therapy directly to the organ.

From Newcastle University 15 Jul 2020

PET reveals the existence of inter-organ communication between the heart and kidneys after heart attack

Whole body positron emission tomography (PET) has, for the first time, illustrated the existence of inter-organ communication between the heart and kidneys via the immune system following acute myocardial infarction, or heart attack.

14 Jul 2020

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

An interventional therapy aimed at improving survival chances and reducing the need for critical care treatment due to COVID-19 is being investigated by physicians at The University of Texas Health Science Center at Houston.

14 Jul 2020

Researchers to develop new ways to prevent esophageal cancer

The incidence of esophageal adenocarcinoma has increased 8-fold over the past 50 years. This is one of the deadliest cancers, with a five-year survival rate of only 20 percent.

14 Jul 2020

Study: Specific mechanism of Cyclocarya paliurus shows promise for treating type 2 diabetes

Type 1 diabetes mellitus and type 2 diabetes mellitus (T2DM) are the two main types of diabetes, while T2DM accounts for 90%-95% of those with diabetes.

14 Jul 2020

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Critically ill COVID-19 patients who received a single dose of a drug that calms an overreacting immune system were 45% less likely to die overall, and more likely to be out of the hospital or off a ventilator one month after treatment, compared with those who didn't receive the drug, according to a new study by a team from the University of Michigan.

14 Jul 2020

Fatty acid can kill cancer cells, study shows

Researchers have demonstrated that a fatty acid called dihomogamma-linolenic acid, or DGLA, can kill human cancer cells.

13 Jul 2020

Study reveals how stem cells are defined by collective cell dynamics

Human life without stem cells is unimaginable. Thanks to stem cells, a cluster of cells turns into an organ, and tissues of the human body can be renewed.

7 Jul 2020

DNA repair tool is tailored to deal with specific type of complex break, study shows

Our cells are constantly dividing, and as they do, the DNA molecule - our genetic code - sometimes gets broken. DNA has twin strands, and a break in both is considered especially dangerous.

7 Jul 2020

Wild strains of salmonella find a backdoor entry into plants

As the world wrestles with the coronavirus (COVID-19) pandemic, which arose after the virus jumped from an animal species to the human species, University of Delaware researchers are learning about new ways other pathogens are jumping from plants to people.

1 Jul 2020

Kidney News and Research

Increased blood lead levels in children are linked to reduced expression of genes

Researchers discover genetic cause of severe auto inflammatory syndrome

Newly discovered biomarkers predict response to immunotherapy in Type 1 diabetes

Detecting rare circulating tumor cells

A new cell-based gene therapy approach to correct hemophilia A

Coronavirus changes structure that prevents cells from detecting it

Study shows how cancer develops resistance to chemotherapy

Genes and cardiovascular health contribute to a person's dementia risk

Small, compact Cas proteins found in bacteriophages are ideal for gene editing

Substances that target oxytocin receptors can help treat various diseases

Stem cell treatment could improve the quality of donor kidneys

PET reveals the existence of inter-organ communication between the heart and kidneys after heart attack

UTHealth physicians study blood pressure drug's efficiency in improving COVID-19 outcomes

Researchers to develop new ways to prevent esophageal cancer

Study: Specific mechanism of Cyclocarya paliurus shows promise for treating type 2 diabetes

Single dose of tocilizumab improves survival in critically ill COVID-19 patients

Fatty acid can kill cancer cells, study shows

Study reveals how stem cells are defined by collective cell dynamics

DNA repair tool is tailored to deal with specific type of complex break, study shows

Wild strains of salmonella find a backdoor entry into plants

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