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Researchers upend the models of cancer metabolism

Tumors consume glucose at high rates, but a team of Vanderbilt researchers has discovered that cancer cells themselves are not the culprit, upending models of cancer metabolism that have been developed and refined over the last 100 years.

8 Apr 2021

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

For a long time, James McKerrow, MD, PhD, dean of the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, has investigated neglected tropical diseases, which are chronic, disabling parasitic infections mainly affecting the poor and underserved communities in developing nations.

5 Apr 2021

Disease-driving B cells play a role in non-alcoholic fatty liver disease

A study by researchers proposes that disease-driving B cells—a kind of white blood cell—have a role in the development of non-alcoholic fatty liver disease.

23 Mar 2021

Non-circulating memory T cells contribute to chronic transplant rejection

The main function of non-circulating memory T cells is to offer local protection against re-infection.

22 Mar 2021

New technological approach to rapidly develop new drugs without animal experiments

A team of researchers led by Professor Yaakov Nahmias, director of the Grass Center for Bioengineering at the Hebrew University of Jerusalem and founder of Tissue Dynamic, introduced a new technological approach that has the potential to rapidly develop new drugs without the need for animal experiments.

10 Mar 2021

New software tool enables swift analysis of datasets generated from single-cell sequencing

A new software tool allows researchers to quickly query datasets generated from single-cell sequencing. Users can identify which cell types any combination of genes are active in.

4 Mar 2021

Daytime napping is partly regulated by a person's genes

How often a person takes daytime naps, if at all, is partly regulated by their genes, according to new research led by investigators at Massachusetts General Hospital (MGH) and published in Nature Communications.

11 Feb 2021

Study provides insights into genetic landscape of common inherited kidney disease

A study has described genetic changes in patients with the most common form of hereditary kidney disease that affects an estimated 12.5 million people worldwide.

10 Feb 2021

Researchers identify three genes regulating stemness of gastric tissue stem cells

Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages.

9 Feb 2021

Study discovers new anti-inflammatory role for well-known blood clot protein

Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases.

2 Feb 2021

Single-dose universal vaccine could protect against many types of leptospirosis bacteria

Scientists have designed a single-dose universal vaccine that could protect against the many forms of leptospirosis bacteria, according to a study published today in eLife.

27 Jan 2021

Study explores why Shiga toxin-producing E. coli infections are so dangerous

E. coli food poisoning is one of the worst food poisonings, causing bloody diarrhea and kidney damage. But all the carnage might be just an unintended side effect, researchers from UConn Health report in the 27 November issue of Science Immunology. Their findings might lead to more effective treatments for this potentially deadly disease.

7 Jan 2021

TUM researcher develops self-learning algorithms to help analyze bioscientific image data

Imaging techniques enable a detailed look inside an organism. But interpreting the data is time-consuming and requires a great deal of experience.

29 Dec 2020

Researchers use different colors of light to control gut bacteria genes

Baylor College of Medicine researcher Meng Wang had already shown that bacteria that make a metabolite called colanic acid (CA) could extend the lifespan of worms in her lab by as much as 50%, but her collaboration with Rice University synthetic biologist Jeffrey Tabor is providing tools to answer the bigger question of how the metabolite imparts longer life.

23 Dec 2020

Kidney News and Research

Researchers upend the models of cancer metabolism

Low K777 concentrations inhibit cathepsin L and reduce SARS-CoV-2’s ability to infect host cell lines

Disease-driving B cells play a role in non-alcoholic fatty liver disease

Non-circulating memory T cells contribute to chronic transplant rejection

New technological approach to rapidly develop new drugs without animal experiments

New software tool enables swift analysis of datasets generated from single-cell sequencing

Daytime napping is partly regulated by a person's genes

Study provides insights into genetic landscape of common inherited kidney disease

Researchers identify three genes regulating stemness of gastric tissue stem cells

Study discovers new anti-inflammatory role for well-known blood clot protein

Single-dose universal vaccine could protect against many types of leptospirosis bacteria

Study explores why Shiga toxin-producing E. coli infections are so dangerous

TUM researcher develops self-learning algorithms to help analyze bioscientific image data

Researchers use different colors of light to control gut bacteria genes

Researchers discover protein that may trigger lung scarring

Tepary beans are identified as a prospective forage and cover crop

Molecular markers in the blood can predict severe COVID-19 outcomes

Glyphosate could be used as biomarkers to predict incurring diseases in future generations

Obesity allows cancer cells to outcompete tumor-killing immune cells, study finds

Cell survival protein could protect the kidneys from 'bystander' damage during cancer therapy

Discovering a new genetic mutation in Schizophrenia

Developing a new CRISPR technique

Monitoring pollen levels using environmental DNA

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