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Researchers reveal how cancerous tissues develop resistance to platinum-based cytotoxic drugs

Cancer cells sometimes develop resistance to the cytotoxic drugs used in chemotherapy. Figuring out why the treatment isn't working and why it may even defeat its own purpose is therefore important to understand.

9 Aug 2021

Researchers identify key enzyme for producing a major industrial chemical in plants

Scientists studying the biochemistry of plant cell walls have identified an enzyme that could turn woody poplar trees into a source for producing a major industrial chemical.

6 Aug 2021

Cytokines play a role in regulation of beige fat

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

6 Aug 2021

Researchers create new drug database to facilitate repurposing of drugs

Scientists developed a new open-access database with information on drug candidates and the process of metabolization of the drugs by the body.

5 Aug 2021

Researchers conduct molecular analysis of the 2021 Bundibugyo virus outbreak

New research offers insight into the origins of the 2012 Bundibugyo viral disease outbreak in the Democratic Republic of the Congo.

4 Aug 2021

Researchers devise a new method for safer delivery of RNA drugs

Scientists have developed and tested a library of lipid-based compounds for the safe and effective delivery of RNA drugs to the lungs.

3 Aug 2021

New study could help develop novel treatments for neurodegenerative diseases

Researchers have introduced a novel gene therapy program that could set the stage for new treatments for neurodegenerative diseases.

2 Aug 2021

Next generation automation lab achieves huge productivity gains

Eli Lilly and Company and their industry partners, including sample management specialists – Ziath, are speeding the discovery of new medicines through the fully automated Lilly Life Sciences Studio lab in San Diego, USA.

From Ziath Ltd 30 Jul 2021

Study analyzes the role of heart cell protein as a potential therapeutic for heart failure

Recent research identified that a protein involved in regulating calcium signaling within heart cells can play a vital role in the prevention of chronic heart failure.

From The University of Utah 29 Jul 2021

T cell-depleted macaques can mount potent memory responses against SARS-CoV-2

New research conducted in monkeys reveals that T cells are not critical for the recovery of primates from acute COVID-19 infections.

28 Jul 2021

Research group analyzes methods to tackle antibiotic resistance

One major threat that the world faces and researchers are working to combat today is antibiotic resistance, and six CSRI students are doing their part in the fight.

28 Jul 2021

ACMG and Elsevier announce new partnership to publish 'Genetics in Medicine'

The American College of Medical Genetics and Genomics, the only nationally recognized US medical professional organization solely dedicated to improving health through the practice of medical genetics and genomics, and Elsevier, a global leader in research publishing and information analytics, are delighted to announce a new partnership to publish ACMG's official journal, Genetics in Medicine.

27 Jul 2021

UKRI invests in research projects that aim to build a sustainable future for marine economy

Six new research projects that aim to build a sustainable future for the marine environment and those whose livelihoods depend on it were announced today.

26 Jul 2021

Study employs llama nanobodies to hunt human cytomegalovirus

Researchers created a “nanobody”, a small fragment of a llama antibody, that can evade human cytomegalovirus as it hides away from the immune system.

26 Jul 2021

Researchers successfully create genetically engineered marsupials via genome editing

Scientists from the RIKEN Center for Biosystems Dynamics Research (BDR) successfully created the first genetically engineered marsupial. The research and its findings published in the Current Biology journal help decipher the genetic background of special characteristics found only in marsupials.

23 Jul 2021

Research identifies vitamin C as a key ingredient for immune cell function

A new study has now identified that it is not possible to generate stable regulatory T cells without Vitamin C or enzymes called TET proteins as much as how one cannot make a banana split without bananas.

23 Jul 2021

Soil microbes are critical players in corn heterosis

The tiny organisms living in soil may have a greater effect on the yield and pest and disease resistance of crop plants grown in that soil than previously known.

22 Jul 2021

Toward an antiviral drug that works against all coronaviruses

Safe and effective vaccines offer hope for an end to the COVID-19 pandemic. However, the possible emergence of vaccine-resistant SARS-CoV-2 variants, as well as novel coronaviruses, make finding treatments that work against all coronaviruses as important as ever.

22 Jul 2021

Researchers discover nucleotide sequences characteristic of microRNA isoforms

Researchers from HSE University have discovered nucleotide sequences characteristic of microRNA isoforms (microRNAs with errors).

22 Jul 2021

New test to detect substances that are harmful to the placenta and embryo

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.

22 Jul 2021