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New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022

The analysis of pesticide residues in cannabis and hemp products

In this interview, Avinash Dalmia, the Senior Principal Application Scientist at PerkinElmer, talks to AZoLifeSciences about the analysis of 102 pesticides and 5 mycotoxin residues in hemp regulated by colorado state.

From PerkinElmer Cannabis & Hemp Testing Solutions 2 Dec 2022

Preventing protein-protein interactions with a new tool

Proteins constantly interact with one another inside cells to perform various tasks. Blocking the binding of two or more proteins appears as a potential treatment for some diseases where these functions are altered.

1 Dec 2022

Using nanotechnology and magnetic manipulations to bioengineer 3D neural networks

Neurons are the fundamental units of the brain and nervous system, the cells responsible for receiving sensory input from the external world, for sending motor commands to our muscles, and for transforming and relaying the electrical signals at every step in between.

30 Nov 2022

Acute infection disrupts the healthy balance between the good and bad gut microbes

Rutgers researchers examined the impact of COVID-19 on patients’ microbiomes, the group of microbes that live in and on the human body.

30 Nov 2022

Discovery provides insights into how invertebrates have evolved complex nervous systems

Octopuses are not much like humans -; they are invertebrates with eight arms, and more closely related to clams and snails.

29 Nov 2022

Study unravels a novel function of the gene scissors

Many years earlier, the CRISPR/Cas9 gene scissors have been making a sensation in science and medicine. This new tool of molecular biology consists of its origins in an ancient bacterial immune system.

28 Nov 2022

Plants can precisely tune the chemistry of petal surface to create bee-luring signals

Cambridge researchers led by CUBG Director, Professor Beverley Glover, have shown that plants can regulate the chemistry of their petal surface to create iridescent signals visible to bees.

25 Nov 2022

Improving potential of cellular therapies with CAR T therapy

CAR T cells, or engineered immune cells, have demonstrated to the world the potential of customized immunotherapies to treat blood cancers. Researchers have just released highly encouraging preliminary data for CAR T therapy in a small group of lupus patients.

25 Nov 2022

Breakthrough on the way to new therapeutic strategies

As far as the field of cancer research is concerned, hollow spheres composed of MYC proteins sets the stage. Researchers from Würzburg have found them out and have reported this discovery in the Nature journal.

25 Nov 2022

RNA-targeting strategy to repair the genetic cause of ALS and dementia

Researchers at UF Scripps Biomedical Research have created a potential treatment for a major factor in the development of ALS and dementia that functions by removing disease-causing RNA segments.

24 Nov 2022

Launch of stem cells into space to investigate stem cell aging

Lab tests on astronaut Scott Kelly’s blood cells after he returned from a year-long stay aboard the International Space Station (ISS) showed telomeric and pre-leukemic changes.

From UC San Diego 24 Nov 2022

Preventing warming by cutting greenhouse gas emissions can save valuable freshwater resource

Snowcapped mountains not only look majestic – They're vital to a delicate ecosystem that has existed for tens of thousands of years.

23 Nov 2022

Chemically attenuated live DNA virus vaccine prevents viral infection

Rutgers researchers have devised a new way to prevent viral infections: a live-attenuated, replication-defective DNA virus vaccine that utilizes the substance centanamycin to create an altered virus for vaccine development.

22 Nov 2022

Atypical antibody shows extremely potent zika-resistant activity

A group of researchers led by Weill Cornell Medicine, New York-Presbyterian, and National Institutes of Health (NIH) investigators has discovered an unusual type of antibody that, even at extremely low concentrations, neutralizes the Zika virus and renders the virus infection undetectable in preclinical models.

22 Nov 2022

Revealing the functional significance of DDX41 in great detail

The DDX41 gene encodes the nuclear enzyme DEAD-box-type RNA helicase. Hematopoietic malignancies are caused by DDX41 mutations. However, the mechanism behind the development of this malignancy remains unknown.

21 Nov 2022

Applying “programmable molecular scissors” to combat COVID-19 infection

As an approach that could be used to create a new class of antiviral drugs, synthetic biology was used by Cambridge scientists to artificially create enzymes programmed to attack the genetic code of SARS-CoV-2 and eliminate the virus.

17 Nov 2022

Researchers create genetic 'devices' to perform computations like artificial neural circuits

Bringing together concepts from electrical engineering and bioengineering tools, Technion and MIT scientists collaborated to produce cells engineered to compute sophisticated functions – "biocomputers" of sorts.

15 Nov 2022

NIH funds research on mRNA vaccines to stop cancer development

The National Cancer Institute at the National Institutes of Health has awarded a multidisciplinary team of Weill Cornell Medicine researchers a five-year $5.7 million grant to support a center dedicated to creating messenger RNA (mRNA) vaccines to prevent the development of cancer in at-risk groups.

15 Nov 2022

Genetically modifying plant protein to yield more vegetable oil

At the Nanyang Technological University, Singapore (NTU Singapore), researchers have been successful in genetically modifying a plant protein that is accountable for oil accumulation in edible nuts and plant seeds.

From Nanyang Technological University Singapore (NTU Singapore) 11 Nov 2022

Laboratory News and Research

New 3D organoid model reveals a possible biological target for treating GEJ cancers

The analysis of pesticide residues in cannabis and hemp products

Preventing protein-protein interactions with a new tool

Using nanotechnology and magnetic manipulations to bioengineer 3D neural networks

Acute infection disrupts the healthy balance between the good and bad gut microbes

Discovery provides insights into how invertebrates have evolved complex nervous systems

Study unravels a novel function of the gene scissors

Plants can precisely tune the chemistry of petal surface to create bee-luring signals

Improving potential of cellular therapies with CAR T therapy

Breakthrough on the way to new therapeutic strategies

RNA-targeting strategy to repair the genetic cause of ALS and dementia

Launch of stem cells into space to investigate stem cell aging

Preventing warming by cutting greenhouse gas emissions can save valuable freshwater resource

Chemically attenuated live DNA virus vaccine prevents viral infection

Atypical antibody shows extremely potent zika-resistant activity

Revealing the functional significance of DDX41 in great detail

Applying “programmable molecular scissors” to combat COVID-19 infection

Researchers create genetic 'devices' to perform computations like artificial neural circuits

NIH funds research on mRNA vaccines to stop cancer development

Genetically modifying plant protein to yield more vegetable oil

Genome Editing Has A New Code

Researchers reveal key developmental difference between the brains of modern humans and Neandertals

Cell Counting Without Slides to Reduce Waste and Cost

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