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New gene editing approach bypasses disease-causing mutations

A new approach to gene editing using the CRISPR/Cas9 system bypasses disease-causing mutations in a gene, enabling treatment of genetic diseases linked to a single gene, such as cystic fibrosis, certain types of sickle cell anemia, and other rare diseases.

From Penn State University 22 Apr 2021

Sustainable green hydrogen to reduce greenhouse gas emissions

It's no secret the carbon emissions that result from using fossil fuels to produce energy are problematic for the planet. One way to make a dent in reducing these greenhouse gas (GHG) emissions is to find renewable ways to power the American manufacturing industry, which today is largely fueled by petroleum and natural gas.

21 Apr 2021

Researchers uncover a key genetic culprit in the development of acute lymphoblastic leukemia

Using a widely known field of mathematics designed mainly to study how digital and other forms of information are measured, stored and shared, scientists at Johns Hopkins Medicine and Johns Hopkins Kimmel Cancer Center say they have uncovered a likely key genetic culprit in the development of acute lymphoblastic leukemia (ALL).

21 Apr 2021

Study shows how tau aggregates promote Alzheimer’s disease

If looked deep into the brain of a patient with Alzheimer’s disease or those suffering from the most types of dementia or the concussion-associated syndrome, called chronic traumatic encephalopathy (CTE), there would be hairball-like tangles of a protein known as tau—a common suspected culprit.

20 Apr 2021

Interferon-stimulating genes control SARS-CoV-2 replication

Researchers have found a set of human genes that combat infection due to SARS-CoV-2, the virus responsible for causing COVID-19.

20 Apr 2021

Supercomputer simulations reveal the behavior of dominant G form SARS-CoV-2 strain

Large-scale supercomputer simulations at the atomic level show that the dominant G form variant of the COVID-19-causing virus is more infectious partly because of its greater ability to readily bind to its target host receptor in the body, compared to other variants.

19 Apr 2021

Household income consistently explains more discrepancy in food security, analysis reveals

One of the most comprehensive statistical analyses of drivers of food insecurity across 65 countries has concluded that household income consistently explains more discrepancy in food security than any other factor, including agricultural land resources and production.

19 Apr 2021

U.S. interstate trade can mitigate the economic effects of climate change

Agricultural producers deal firsthand with changing weather conditions, and extreme events such as drought or flooding can impact their productivity and profit. Climate change models project such events will occur more often in the future.

19 Apr 2021

“Expansion Hunter” approach can detect DNA errors

Researchers from Radboud University Medical Center have successfully detected hidden genetic defects by using an existing technique on existing datasets. The team demonstrated that the “Expansion Hunter” approach can detect DNA errors that cause repeat expansion diseases, like ataxia—a movement disorder.

16 Apr 2021

Researchers use information embedded in microbial genes as a biosensor of ocean health, productivity

Scientists from the University of California, Irvine, analyzed gains and losses in the genes of phytoplankton samples gathered from all major ocean regions to develop the most refined and highest-resolution map that shows where these photosynthetic organisms either survive or are forced to adapt to restricted amounts of main nutrients, nitrogen, iron, and phosphorus.

16 Apr 2021

Growing chimeric embryos could offer new insights into developmental biology, evolution

Scientists from China and the United States have been able to grow chimeric embryos for a considerable period of time—of up to 20 days—by injecting human stem cells into primate embryos.

16 Apr 2021

Study reveals how some antibodies can effectively disable ebolaviruses

Some survivors of ebolavirus outbreaks make antibodies that can broadly neutralize these viruses--and now, scientists at Scripps Research have illuminated how these antibodies can disable the viruses so effectively. The insights may be helpful for developing effective therapies.

16 Apr 2021

DNAJC9 protein plays a key role in protecting histones in the cell nucleus

Histones play an important role in the cell nucleus by packaging DNA into chromatin.

15 Apr 2021

Study reveals RNA regulatory mechanisms within transcription-translation couplings

To gain a better understanding of how bacterial RNA gives rise to proteins scientists are now focusing on the special way this process takes place in bacteria.

15 Apr 2021

Novel method to activate and visualize protein channels that keep bacteria alive

Almost all bacteria rely on the same emergency valves--protein channels that pop open under pressure, releasing a deluge of cell contents.

15 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

Researchers have genetically engineered a probiotic yeast to produce beta-carotene in the guts of laboratory mice. The advance demonstrates the utility of work the researchers have done to detail how a suite of genetic engineering tools can be used to modify the yeast.

13 Apr 2021

CSHL investigator aims to predict the effects of mutations on different tomato varieties

Both people and tomatoes come in different shapes and sizes. That is because every individual has a unique set of genetic variations--mutations--that affect how genes act and function. Added together, millions of small genetic variations make it hard to predict how a particular mutation will impact any individual.

13 Apr 2021

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Researchers from the National Institutes of Health have identified and tested a drug combination that exploits a weakness in small cell lung cancer (SCLC), an aggressive, dangerous cancer.

13 Apr 2021

Scanning & Decoding Tube Racks Direct from Low Temperature Storage

Ziath has posted a new video that provides an easy-to-follow guide to assist scientists and technicians scanning and decoding sample tube racks direct from low-temperature storage.

From Ziath Ltd 9 Apr 2021

Laboratory News and Research

New gene editing approach bypasses disease-causing mutations

Sustainable green hydrogen to reduce greenhouse gas emissions

Researchers uncover a key genetic culprit in the development of acute lymphoblastic leukemia

Study shows how tau aggregates promote Alzheimer’s disease

Interferon-stimulating genes control SARS-CoV-2 replication

Supercomputer simulations reveal the behavior of dominant G form SARS-CoV-2 strain

Household income consistently explains more discrepancy in food security, analysis reveals

U.S. interstate trade can mitigate the economic effects of climate change

“Expansion Hunter” approach can detect DNA errors

Researchers use information embedded in microbial genes as a biosensor of ocean health, productivity

Growing chimeric embryos could offer new insights into developmental biology, evolution

Study reveals how some antibodies can effectively disable ebolaviruses

DNAJC9 protein plays a key role in protecting histones in the cell nucleus

Study reveals RNA regulatory mechanisms within transcription-translation couplings

Novel method to activate and visualize protein channels that keep bacteria alive

Novel test detects HIV reservoir in patients more accurately

Scientists engineer probiotic yeast to produce beta-carotene in the guts of mice

CSHL investigator aims to predict the effects of mutations on different tomato varieties

Researchers identify and test drug combination that exploits a weakness in small cell lung cancer

Scanning & Decoding Tube Racks Direct from Low Temperature Storage

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