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Genomic changes in advanced tumors reveal interactions with treatment

A novel way to look at cancer treatment resistance offers the possibility for identifying genetic mechanisms involved and alternative treatment approaches.

17 Nov 2021

Diet has a much stronger impact on the inner workings of cells than drugs

A study comparing the impact of diet versus drugs on the inner workings of our cells has found nutrition has a much stronger impact.

17 Nov 2021

Green tea catechins extend the lifespan of C. elegans

Aging-US published "Green tea catechins EGCG and ECG enhance the fitness and lifespan of Caenorhabditis elegans by complex I inhibition" which reported that green tea catechins are associated with a delay in aging.

15 Nov 2021

Scientists discover new genetic link to non-alcoholic inflammatory liver disease

Non-alcoholic fatty liver disease (NAFLD) is the accumulation of fat in the liver unrelated to alcohol abuse or other liver diseases.

11 Nov 2021

Targeting Shp2 as a cancer therapy may worsen the disease

In recent years, much scientific effort and funding has focused on developing drugs that target an enzyme with the unwieldy name of Src homology 2-containing protein tyrosine phosphatase 2 or more briefly, Shp2.

10 Nov 2021

Tough protein connects directly with neurons to cause damaging inflammatory reaction in the brain

Neuroinflammatory diseases, including Alzheimer's disease and traumatic brain injury, have been linked to deposits of a tough protein known as fibrin, derived from the blood clotting factor fibrinogen.

9 Nov 2021

CN Bio and iiCON announce COVID-19 research collaboration

CN Bio, a leading Organ-on-a-chip Company (OOC) that designs and manufactures single- and multi-organ microphysiological systems (MPS), today announced a research collaboration with the Infection Innovation Consortium (iiCON), a global collaborative infectious disease R&D programme, to validate the next generation of COVID-19 research tools.

From CN Bio Innovations Limited 9 Nov 2021

Researchers employ hepatic organoids for disease modeling

Associate Professor Tamer Önder created and analyzed the hepatic organoid culture system utilizing human induced pluripotent stem cell as an intermediate.

8 Nov 2021

Brown fat protects against secondary obesity-related diseases, says study

Research demonstrated that obese individuals with active brown fat possess a healthier metabolism and utilize more energy than obese people without.

8 Nov 2021

Generating Cell Repellent Surfaces in Microfluidic Devices

AMSBIO report that researchers from the Medical University of Vienna (Austria), have used Lipidure® - CM5206 to coat channels in their novel microfluidic devices, to prevent cell adhesion.

From AMS Biotechnology 5 Nov 2021

Simultaneously Measuring 7,000 Proteins: Groundbreaking Proteomics from SomaLogic

In this interview, we speak to Roy Smythe, CEO of SomaLogic, about their groundbreaking proteomics technology that can simultaneously measure 7,000 proteins.

From SomaLogic 4 Nov 2021

Study reveals how glycogen is linked to thermogenesis in fat cells

Humans carry around with them, often abundantly so, at least two kinds of fat tissue: white and brown. White fat cells are essentially inert containers for energy stored in the form of a single large, oily droplet.

28 Oct 2021

Consecutive irradiation with two lasers results in increased stem cell proliferation and differentiation

Stem cell therapy needs a lot of human cells, of a specific type. Shining a near-infrared laser on adult stem cells derived from human body fat, makes the stem cells replicate 54% faster.

27 Oct 2021

Researchers map proteo-genomic connections between different human diseases

Hundreds of connections between different human diseases have been uncovered through their shared origin in our genome by an international research team led by scientists from the Medical Research Council (MRC) Epidemiology Unit at the University of Cambridge, challenging the categorisation of diseases by organ, symptoms, or clinical speciality.

18 Oct 2021

Study identifies DNA mutations that impact metabolism and insulin sensitivity in liver disease patients

For the first time, DNA mutations in liver cells have been identified that impact metabolism and insulin sensitivity in patients with liver disease.

15 Oct 2021

Oral diuretic pill may potentially be repurposed to treat Alzheimer's in people with genetic risk

A commonly available oral diuretic pill approved by the U.S. Food and Drug Administration may be a potential candidate for an Alzheimer's disease treatment for those who are at genetic risk, according to findings published in Nature Aging.

12 Oct 2021

Researchers devise simple and rapid method for detecting bovine amyloid

Amyloidosis, a multifaceted disease group results due to the misfolded “amyloid” protein deposits in different tissues.

8 Oct 2021

New gel enhances immunotherapy's effectiveness in glioblastoma

Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues.

7 Oct 2021

Scientists identify novel nairovirus associated with acute febrile illness in Japan

A previously unknown virus that can infect humans and cause disease has been identified by scientists in Japan.

5 Oct 2021

Study sheds light on blood and immune systems development in prenatal bone marrow

Researchers carried out the first extensive investigation of the formation of the blood and immune systems in the prenatal bone marrow.

4 Oct 2021