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The Pathogenic Mechanism Underpinning MEPAN Syndrome

New research published in Nature Metabolism discovered the pathogenic mechanism driving mitochondrial enoyl reductase protein-associated neurodegeneration (MEPAN) syndrome, a rare pediatric neurodegenerative disease.

1 Sep 2023

New Gene Therapy Shows Promise in Treating Gliomas

The University of Michigan Department of Neurosurgery and Rogel Cancer Center study demonstrates enticing early results that a therapy merging cell-killing and immune-stimulating drugs is effective and safe in prolonging survival for patients with gliomas, an extremely aggressive form of brain cancer.

1 Sep 2023

Case Western Reserve Biochemists Find New Approach to Stop Cancer Growth

Case Western Reserve University biochemical researchers have identified a new function of a key protein that leads to cancer–a finding they believe could lead to more effective treatments for a range of cancers and other diseases.

1 Sep 2023

MAGE Technology Helps Reveal the Potency of Antibiotics

By substituting each of the 20 amino acid alternatives found in nature for one of the 38 amino acid components that make up the rifampicin binding site on E. coli, the study authors were able to produce 760 distinct RNAP mutants. The development of this mutant pool was then examined under various circumstances, including rifampicin therapy.

31 Aug 2023

Crick Researchers Identify Stem Cells in Thymus for First Time

For the first time, Francis Crick Institute researchers have discovered stem cells in the human thymus. These cells provide a possible new target for research into immunological disorders, cancer, and immune system stimulation.

31 Aug 2023

Discovery on Learning and Memory Could Lead to New Alzheimer's Treatments

Scientists at the University of Colorado Anschutz Medical Campus have made a `paradigm shifting’ discovery on the mechanisms required for learning and memory that could lead to new therapies for Alzheimer’s disease and potentially Down syndrome.

31 Aug 2023

Solving the Dog Epigenome with INTEGRA Biosciences’ Vacuum Aspirations Systems

Researchers in the Cho Lab at Seoul National University’s College of Veterinary Medicine, are using the VACUSAFE safe aspiration system and VACUSIP portable aspiration system from INTEGRA Biosciences to help them culture organoids from cancer-stricken domesticated dogs as part of a comparative medicine research initiative.

30 Aug 2023

Genetic Risk of Depression Linked to Increased Risk of Other Psychiatric Disorders

Recent research reveals that people who are hospitalized for depression are at an increased risk of developing conditions like substance abuse, bipolar disorder, schizophrenia, and anxiety, depending on their genetic predisposition to the individual disorder.

30 Aug 2023

Case Study Highlights Challenges of Accessing Venom Immunotherapy for Fire Ant Allergies

A recent case study published in the Journal of Allergy and Clinical Immunology: In Practice highlights the challenges faced by families seeking venom immunotherapy for fire ant allergies.

28 Aug 2023

Age-Related Hearing Loss Associated With Decrease of Cholesterol in the Inner Ear

Researchers led by María Eugenia Gomez-Casati, the Institute of Pharmacology, School of Medicine, University of Buenos Aires-CONICET; Mauricio Martin, the Institute of Medical Research Mercedes; and Martín Ferreyra, (INIMEC-CONICET-UNC), National University of Córdoba in Argentina report that age-related hearing loss is associated with a decrease of cholesterol in the inner ear.

25 Aug 2023

Study Identifies 39 Genetic Mutations Associated With Heart Failure

In a new study co-led by investigators at the United States Department of Veterans Affairs and Brigham and Women's Hospital, a founding member of the Mass General Brigham healthcare system, a global team of scientists conducted one of the largest genetic association studies on heart failure to date.

25 Aug 2023

Study Shows How Genomic Topography Influences Where Cancer Mutations Arise

Researchers at the University of California San Diego have uncovered a connection between the topography of the human genome and the presence of mutations in human cancer. They found that certain regions of the genome, which exhibit unique features, act as hotspots for the accumulation of mutations.

25 Aug 2023

Scientists Uncover New Mechanism for Degrading Short-Lived Proteins

Short-lived proteins control gene expression in cells to carry out a number of vital tasks, from helping the brain form connections to helping the body mount an immune defense. These proteins are made in the nucleus and are quickly destroyed once they've done their job.

25 Aug 2023

Naked Mole Rat Gene Boosts Mouse Health and Longevity

University of Rochester scientists have successfully transmitted a longevity gene from naked mole rats to mice, resulting in better health and an extension of the mouse’s lifespan.

24 Aug 2023

Waters Launches XBridge Premier GTx BEH SEC Columns for Gene Therapy Applications

Waters Corporation introduced the first in a new line of size exclusion chromatography (SEC) columns aimed at improving the analysis while lowering the cost of gene therapies, specifically adeno-associated viral (AAV) vectors.

From Waters Corporation 24 Aug 2023

High Levels of Exposure to the Virus Causing COVID-19 May Reduce Safety Given by Vaccination

High levels of exposure to the virus that causes COVID-19 may reduce or overcome the protection that vaccination and prior infection provides, according to a new study by researchers from Yale University, the University of Florida, and the Connecticut Department of Correction.

24 Aug 2023

Sensory Neurons Develop Customized Nerve Endings Based on Cues From the Skin, Finds Study

Nerve cells that sense touch grow the appropriate endings for hairy or hairless skin based on cues from the skin itself, rather than through predetermined programming, according to research led by Harvard Medical School scientists and published Aug. 21 in Developmental Cell.

23 Aug 2023

Study Solves Mystery and Establish the Mechanism Underlying SLC29A3 Disorders

In humans, the SLC29A3 gene regulates the function of lysosomes to control waste recycling in cells such as macrophages (that engulf and destroy foreign bodies).

23 Aug 2023

Analyzing the First Vaccine Against Respiratory Syncytial Virus in Many Older Adults

The first Americans over age 60 just started rolling up their sleeves to get vaccinated against respiratory syncytial virus, or RSV, now that brand-new vaccines have started to arrive at pharmacies and clinics.

23 Aug 2023

CureMD to Integrate Tempus' Advanced Genomic Testing Capabilities Into EHR System

CureMD, a leading provider of comprehensive technology solutions for community oncology, is proud to announce its partnership with Tempus, a leader in artificial intelligence and precision medicine, to integrate Tempus' advanced genomic testing capabilities into CureMD's cutting-edge Electronic Health Record (EHR) system.

23 Aug 2023

Medicine News and Research

The Pathogenic Mechanism Underpinning MEPAN Syndrome

New Gene Therapy Shows Promise in Treating Gliomas

Case Western Reserve Biochemists Find New Approach to Stop Cancer Growth

MAGE Technology Helps Reveal the Potency of Antibiotics

Crick Researchers Identify Stem Cells in Thymus for First Time

Discovery on Learning and Memory Could Lead to New Alzheimer's Treatments

Solving the Dog Epigenome with INTEGRA Biosciences’ Vacuum Aspirations Systems

Genetic Risk of Depression Linked to Increased Risk of Other Psychiatric Disorders

Case Study Highlights Challenges of Accessing Venom Immunotherapy for Fire Ant Allergies

Age-Related Hearing Loss Associated With Decrease of Cholesterol in the Inner Ear

Study Identifies 39 Genetic Mutations Associated With Heart Failure

Study Shows How Genomic Topography Influences Where Cancer Mutations Arise

Scientists Uncover New Mechanism for Degrading Short-Lived Proteins

Naked Mole Rat Gene Boosts Mouse Health and Longevity

Waters Launches XBridge Premier GTx BEH SEC Columns for Gene Therapy Applications

High Levels of Exposure to the Virus Causing COVID-19 May Reduce Safety Given by Vaccination

Sensory Neurons Develop Customized Nerve Endings Based on Cues From the Skin, Finds Study

Study Solves Mystery and Establish the Mechanism Underlying SLC29A3 Disorders

Analyzing the First Vaccine Against Respiratory Syncytial Virus in Many Older Adults

CureMD to Integrate Tempus' Advanced Genomic Testing Capabilities Into EHR System

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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