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Immune System's Standby Mode: Healthy Tissue Keeps Defenses Ready

When pathogens invade the body, the immune system must react immediately to prevent or contain an infection.

25 Apr 2024

Sphingolipid Mystery Solved: S1P May Protect Against Coronary Artery Disease

Weill Cornell Medicine investigators have uncovered a way to unleash in blood vessels the protective effects of a type of fat-related molecule known as a sphingolipid, suggesting a promising new strategy for the treatment of coronary artery disease.

25 Apr 2024

Ancient Gene Holds Key to Mammalian Gliding

People say "When pigs fly" to describe the impossible. But even if most mammals are landlubbers, the ability to glide or fly has evolved again and again during mammalian evolution, in species ranging from bats to flying squirrels.

25 Apr 2024

Hydrogel Therapy: A Novel Defense Against Viral Infections

Vaccines remain the gold standard of protection against dangerous pathogens, but take considerable time and vast resources to develop.

24 Apr 2024

Using State-of-the Art Imaging to Understand Lipid Dysfunction in Alzheimer's

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

24 Apr 2024

Small RNA-Binding Protein Promotes Prime Editing Efficiency

Through years of engineering gene-editing systems, researchers have developed a suite of tools that enable the modification of genomes in living cells, akin to 'genome surgery'.

23 Apr 2024

First Comprehensive Map of Protein Movement in Yeast Cell Cycle Revealed

An international team led by researchers at the University of Toronto has mapped the movement of proteins encoded by the yeast genome throughout its cell cycle.

23 Apr 2024

Study Uncovers Cells' Surprising Strategy to Control Signaling Pathways

Healthy cells respond appropriately to changes in their environment. They do this by sensing what's happening outside and relaying a command to the precise biomolecule in the precise domain that can carry out the necessary response.

23 Apr 2024

Revealing the Genetic Mechanisms Driving SARS-CoV-2 Variants

The SARS-CoV-2 virus, responsible for COVID-19, exhibits a troubling tendency to produce variants frequently.

23 Apr 2024

Researchers Decode Brain Processes Behind Foraging Behavior in Monkeys

While foraging, animals including humans and monkeys are continuously making decisions about where to search for food and when to move among possible sources of sustenance.

22 Apr 2024

Enhancing Drug Discovery Through Automated Protein Labeling

Exact protein observation in cells is crucial for many scientific fields, but it has proven to be a difficult technical task, particularly in living cells where each protein needs to have its fluorescent label applied separately.

22 Apr 2024

Soil Bacteria Use Umbrella Toxins to Fight Back

Scientists have found that soil bacteria called Streptomyces secrete toxic protein particles in the shape of umbrellas that are meant to suppress competitors, particularly those that belong to their species.

18 Apr 2024

KIT Researchers Uncover New Cell Type Responsible for Vascular Growth

Cardiovascular diseases, including stroke and myocardial infarction, are the world's leading causes of mortality, accounting for over 18 million deaths a year.

18 Apr 2024

U of T Scientists Make Breakthrough Discovery in DNA Repair Mechanism

Researchers at the University of Toronto have discovered a DNA repair mechanism that advances understanding of how human cells stay healthy, and which could lead to new treatments for cancer and premature aging.

18 Apr 2024

New Method Reveals Dynamic Protein Structures in Real Time

Researchers at Weill Cornell Medicine have developed a powerful, new technique to generate "movies" of changing protein structures and speeds of up to 50 frames per second.

17 Apr 2024

Understanding How the Human Forebrain Develops at the Cellular Level

A group of researchers at University of California San Diego School of Medicine led an investigation that offers new insight into the development of the human forebrain.

17 Apr 2024

Placenta's Role in Gestational Diabetes Revealed

A recent study led by the Harvard Pilgrim Health Care Institute has discovered that a deficiency in placental expression of the gene insulin-like growth factor 1 (IGFBP1) and low circulating levels of IGFBP1 are linked to insulin resistance during pregnancy, indicating a potential risk factor for the onset of gestational diabetes.

17 Apr 2024

Bacterial "Vampirism" Fuels Deadly Infections

The world's deadliest bacteria actively seek out human blood to feed on, a phenomenon that scientists are referring to as “bacterial vampirism”.

17 Apr 2024

What Makes Certain Mushrooms 'Magic'?

In a recent study published in the journal Nature Communications, an international research team from various Universities including Hans Knöll Institute investigated the biosynthesis of psilocybin, the primary component of hallucinogenic mushrooms.

17 Apr 2024

First Single-Cell Atlas for the Water Nymph Worm Published

An international team of scientists including B. Duygu Özpolat at Washington University in St. Louis has published the first single-cell atlas for Pristina leidyi (Pristina), the water nymph worm, a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.

16 Apr 2024