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Study shows potential of human mesenchymal stem cells in treating NTM lung infection

A study released today in STEM CELLS Translational Medicine offers hope for those suffering from a chronic, difficult to treat condition called non-tuberculous mycobacteria (NTM) lung infection.

5 May 2021

Study reveals genetic mutation associated with exfoliation syndrome

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore (GIS) and Bioprocessing Technology Institute (BTI), as well as Singapore Eye Research Institute (SERI), have identified a genetic mutation (functionally defective CYP39A1 gene) associated with exfoliation syndrome, the most common cause of glaucoma.

5 May 2021

Abnormal fetal development is regulated by genetics, not the intrauterine environment

The genetics of the placenta and fetus, not the mother’s intrauterine environment, regulate developmental abnormalities, including those that contribute to pregnancy loss.

5 May 2021

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

Researchers devise a small-molecule cocktail to protect stem cells from stress

Researchers at the National Institutes of Health (NIH) have devised a four-part small-molecule cocktail that can protect stem cells called induced pluripotent stem cells (iPSCs) from stress and maintain normal stem cell structure and function.

4 May 2021

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Geisinger receives $3.6 million from NCI to study the role of genetic variation in cancer

The National Cancer Institute, part of the National Institutes of Health, has awarded a 5-year, $3.6 million contract to Geisinger to study the role of genetic variation in cancer.

30 Apr 2021

Genetically encoded sensor helps detect hallucinogenic substances

Researchers at the University of California, Davis, have created a genetically encoded sensor for detecting hallucinogenic substances.

29 Apr 2021

New synthetic biology study allows bio-manufacturing advancements for medicine and engineering

A new synthetic biology study sponsored by the U.S. Army exploited micro-compartments in cells, prospectively allowing advances in bio-manufacturing for applications such as engineering, medicine, and protective equipment.

29 Apr 2021

Increased expression of DUSP16 molecule leads to cancer chemoresistance

Chemotherapy is a drug treatment that uses powerful chemicals to kill fast-growing cancer cells in the body. It is a systemic treatment where drugs travel throughout the body and destroy cancer cells that have spread (metastasized) to parts of the body far away from the original (primary) tumour.

28 Apr 2021

New, altered form of prolactin receptor found to drive breast cancer

Prolactin is a hormone that has long been thought to play an important role in breast development and growth, as well as milk production during pregnancy.

27 Apr 2021

Study shows that autophagy plays a key role in messenger RNA degradation

Autophagy is essential in messenger RNA (mRNA) degradation, according to researchers from the Tokyo Institute of Technology (Tokyo Tech).

27 Apr 2021

New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

A new way to identify tumors that could be sensitive to particular immunotherapies has been developed using data from thousands of NHS cancer patient samples sequenced through the 100,000 Genomes Project.

27 Apr 2021

Cell adaptation to adverse conditions could differentiate survivors and non-survivors of critical illness

Creating the best conditions for cells to make energy and survive critical illness is a challenge little understood in modern medicine.

27 Apr 2021

Researchers hope to make estrogen therapy a more accessible treatment for breast cancer patients

Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center (NCCC) hope to make estrogen therapy a more accessible treatment option for breast cancer patients who could benefit from it.

26 Apr 2021

Protein in skeletal muscular system may play a key role in the body's fight or flight response

Researchers at the University of Cincinnati say a regulatory protein found in skeletal muscle fiber may play an important role in the body's fight or flight response when encountering stressful situations.

26 Apr 2021

National DNA Day 2021: The Importance of DNA in Research

To celebrate National DNA Day, AZoLifeSciences speaks to Belen Hurle from the National Human Genome Research Institute about the importance of DNA in research.

26 Apr 2021

Small molecular changes can have dramatic impact on the CAR T cell function

When researchers from Penn Medicine found that many patients with B-cell acute lymphoblastic leukemia (ALL) treated with the investigational chimeric antigen receptor (CAR) T cell therapy targeting the CD22 antigen didn't respond, they went back to the drawing board to determine why.

23 Apr 2021

National DNA Day 2021: An Interview with Professor George Church

In celebration of National DNA Day, AZoLifeSciences interviews renowned DNA expert Professor George Church about his life-long career in DNA research.

23 Apr 2021

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Research teams investigated the antibodies generated in people with symptomatic or asymptomatic SARS-CoV-2 infection.

23 Apr 2021

Medicine News and Research

Study shows potential of human mesenchymal stem cells in treating NTM lung infection

Study reveals genetic mutation associated with exfoliation syndrome

Abnormal fetal development is regulated by genetics, not the intrauterine environment

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

Researchers devise a small-molecule cocktail to protect stem cells from stress

New integrative genetic screening technology offers insights into role of DNA accessibility in cancer

Geisinger receives $3.6 million from NCI to study the role of genetic variation in cancer

Genetically encoded sensor helps detect hallucinogenic substances

New synthetic biology study allows bio-manufacturing advancements for medicine and engineering

Increased expression of DUSP16 molecule leads to cancer chemoresistance

New, altered form of prolactin receptor found to drive breast cancer

Study shows that autophagy plays a key role in messenger RNA degradation

New computer algorithm helps identify tumors with 'mismatch repair deficiencies'

Cell adaptation to adverse conditions could differentiate survivors and non-survivors of critical illness

Researchers hope to make estrogen therapy a more accessible treatment for breast cancer patients

Protein in skeletal muscular system may play a key role in the body's fight or flight response

National DNA Day 2021: The Importance of DNA in Research

Small molecular changes can have dramatic impact on the CAR T cell function

National DNA Day 2021: An Interview with Professor George Church

SARS-CoV-2 infection produces antibodies that can destroy infected cells

Developing a portable tool to detect street drug ‘spice’

National DNA Day: Importance of DNA in Research

National DNA Day 2021: An Interview with Professor George Church

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