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Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Past exposure to seasonal coronaviruses (CoVs), which cause the common cold, does not result in the production of antibodies that protect against the novel coronavirus SARS-CoV-2, according to a study led by Scott Hensley, PhD, an associate professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania.

11 Feb 2021

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

For all their importance as a breakthrough treatment, the cancer immunotherapies known as checkpoint inhibitors still only benefit a small minority of patients, perhaps 15 percent across different types of cancer. Moreover, doctors cannot accurately predict which of their patients will respond.

11 Feb 2021

Study examines the largest and most diverse genetic sequencing data sets

Researchers at the University of Maryland School of Medicine (UMSOM) and their colleagues published a new analysis today in the journal Nature from genetic sequencing data of more than 53,000 individuals, primarily from minority populations.

11 Feb 2021

Unusual DNA folding leads to higher mutation rates

DNA sequences that can fold into shapes other than the classic double helix tend to have higher mutation rates than other regions in the human genome.

From Penn State University 10 Feb 2021

Study provides insights into genetic landscape of common inherited kidney disease

A study has described genetic changes in patients with the most common form of hereditary kidney disease that affects an estimated 12.5 million people worldwide.

10 Feb 2021

Bernese researchers create sophisticated lung-on-chip

The lung is a complex organ whose main function is to exchange gases. It is the largest organ in the human body and plays a key role in the oxygenation of all the organs.

10 Feb 2021

New platform may accelerate genomic medicine research, drug therapies

A research team, headed by Cleveland Clinic, has designed a novel personalized genomic medicine platform that would help speed up genomic medicine studies as well as genome-informed drug discovery. The results of the new study have been recently published in the Genome Biology journal.

9 Feb 2021

Study reveals genetic factors linked to COVID-19 susceptibility in people with Down syndrome

A study reveals the genetic factors that may expose or protect people with Down syndrome from SARS-CoV-2 infection, as well as the prognosis of COVID-19.

9 Feb 2021

Researchers identify three genes regulating stemness of gastric tissue stem cells

Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages.

9 Feb 2021

Study suggests the need to characterize patient-specific responses to respiratory syncytial virus

Researchers at Baylor College of Medicine found that while most individuals responded to respiratory syncytial virus (RSV) natural reinfection with a typical sustained antibody response associated with protection, a few individuals surprisingly responded atypically, not being able to sustain the antibody response, which declined to levels that made the individuals susceptible to RSV reinfection.

5 Feb 2021

AI analyzes tissue scans to identify cancer patients at risk of hyperprogressive disease

Researchers at Case Western Reserve University, using artificial intelligence (AI) to analyze simple tissue scans, say they have discovered biomarkers that could tell doctors which lung cancer patients might actually get worse from immunotherapy.

5 Feb 2021

Study provides a causal link between the Alzheimer's risk gene and COVID-19

A City of Hope-led research team found that the same gene that increases the risk for Alzheimer's disease, ApoE4, can increase the susceptibility to and severity of COVID-19.

5 Feb 2021

Ancestral backgrounds can influence Alzheimer's disease risk, finds study

Genetics contributes to the risk of developing Alzheimer's disease, and the APOE gene is the strongest genetic risk factor, specifically the APOE4 allele.

5 Feb 2021

New report highlights coffee's effect on sleep

The Institute for Scientific Information on Coffee (ISIC) published a new report today, titled 'Coffee and sleep in everyday lives', authored by Professor Renata Riha, from the Department of Sleep Medicine at the University of Edinburgh.

5 Feb 2021

Study shows strong link between genetic changes and cerebral palsy

Scientists have identified a strong connection between genetic modifications known to cause cerebral palsy and neurodevelopmental disabilities.

3 Feb 2021

Breast cancer-on-a-chip for rapid screening of immunotherapeutic drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins."

3 Feb 2021

Study discovers new anti-inflammatory role for well-known blood clot protein

Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases.

2 Feb 2021

Intensive BP lowering effective in reducing cardiovascular risk in patients exposed to air pollution

Evidence suggests particulate matter is the air pollutant which poses the greatest threat to global health. Studies have shown that exposure to particulate matter smaller than 2.5 microns is associated with acute and chronic elevations in blood pressure (BP) as well as hypertension.

2 Feb 2021

Yale scientists discover novel metabolic gatekeeper mechanism for leukemia

In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. The findings were published online today in the Proceedings of the National Academy of Sciences (PNAS).

2 Feb 2021

Scientists identify specific genes associated with post-traumatic stress disorder

A research team has found 18 specific, fixed positions on chromosomes (called loci) that seem to be linked to post-traumatic stress disorder (PTSD).

29 Jan 2021

Medicine News and Research

Seasonal human coronavirus antibodies not associated with protection against SARS-CoV-2

Inherited genetic variation plays a role in how patients respond to cancer immunotherapy

Study examines the largest and most diverse genetic sequencing data sets

Unusual DNA folding leads to higher mutation rates

Study provides insights into genetic landscape of common inherited kidney disease

Bernese researchers create sophisticated lung-on-chip

New platform may accelerate genomic medicine research, drug therapies

Study reveals genetic factors linked to COVID-19 susceptibility in people with Down syndrome

Researchers identify three genes regulating stemness of gastric tissue stem cells

Study suggests the need to characterize patient-specific responses to respiratory syncytial virus

AI analyzes tissue scans to identify cancer patients at risk of hyperprogressive disease

Study provides a causal link between the Alzheimer's risk gene and COVID-19

Ancestral backgrounds can influence Alzheimer's disease risk, finds study

New report highlights coffee's effect on sleep

Study shows strong link between genetic changes and cerebral palsy

Breast cancer-on-a-chip for rapid screening of immunotherapeutic drugs

Study discovers new anti-inflammatory role for well-known blood clot protein

Intensive BP lowering effective in reducing cardiovascular risk in patients exposed to air pollution

Yale scientists discover novel metabolic gatekeeper mechanism for leukemia

Scientists identify specific genes associated with post-traumatic stress disorder

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