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Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

Researchers design antibody to identify pathogens of Alzheimer's disease

Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.

26 May 2020

New model mimics early embryonic stages of the human brain

We know a lot about the human brain, but very little about how it is formed. In particular, the stages from the second to the seventh week of embryonic development have so far been virtually unknown territory to brain researchers.

26 May 2020

Using light to control the viability and mobility of individual cells

Photopharmacology is the study that examines the use of light to change the impact of drugs on and off. For the first time, researchers from Jena, Munich, and New York have successfully applied this technique to regulate a component of cells that was earlier believed to be inaccessible.

18 May 2020

Study reveals nuanced role for oncogene in contact inhibition

Like subway com muters on a crowded train, cells generally prefer not to be packed in too tightly. In fact, they have set up mechanisms to avoid this, a phenomenon called "contact inhibition."

15 May 2020

Inflammatory cells arise from local memory cells in people with long-term multiple sclerosis

In the brains of people that suffer from long-term multiple sclerosis (MS), inflammatory cells are not entering the brain via the bloodstream anymore.

15 May 2020

New approach provides closer look at the development of multicellular organisms

Highly complex organisms can arise from a single cell, which is one of the true miracles of nature. Substances known as morphogens have an important role in this development, namely by signaling to cells where they should go and what they should do.

13 May 2020

Lipid metabolism enzyme regulates brain stem cell activity

Neural stem cells play a major role in the early development of the brain and they also continue to remain active throughout the lifetime.

11 May 2020

Foxg1 gene works like a molecular knob to modulate electrical activity of the neurons

It works like a very fine "molecular knob" able to modulate the electrical activity of the neurons of our cerebral cortex, crucial to the functioning of our brain.

8 May 2020

Newly discovered gene variants offer therapeutic possibilities for glaucoma

An international team of researchers, headed by scientists from Stanford University and the University of Helsinki, has discovered unique changes in a gene, known as ANGPTL7, that reduce intraocular pressure and considerably decrease the risk of glaucoma.

6 May 2020

Spinal Cord Injuries: Finding Better Treatments

Two scientists are seeking answers to questions about spinal cord injuries that have long frustrated the development of effective treatments.

1 May 2020

Immune System Changes Occur Early In Development Of Multiple Myeloma

Before multiple myeloma becomes a malignant disease, the collection of immune system cells and signal carriers amid the tumor cells undergo dramatic shifts.

29 Apr 2020

Specialized Nerve Cells Increase The Appetite For High-Fat Foods

Researchers have discovered that a group of nerve cells promotes the consumption of high-fat food.

24 Apr 2020

How do cells react to stressful conditions?

Most often, cells are subjected to stressful conditions that can pose a serious threat to life, for example, toxins or high temperatures.

23 Apr 2020

Biophysicists uncover new features of molecular elevator

Biophysicists from the Moscow Institute of Physics and Technology and the University of Groningen in the Netherlands have visualized a nearly complete transport cycle of the mammalian glutamate transporter homolog from archaea.

21 Apr 2020

A ‘virtual embryo’ for unprecedented single-cell studies

Researchers from EMBL Heidelberg and from the University of Padua School of Medicine have created the first complete description of early embryo development, accounting for every single cell in the embryo.

21 Apr 2020

UTSW researchers solve structure of key protein involved in muscle contraction

Researchers at UT Southwestern Medical Center have uncovered the detailed shape of a key protein involved in muscle contraction.

16 Apr 2020

Why do artificial sweeteners fail to satisfy sugar cravings?

A small quantity of extra sugar would be enough to make people crave for almost everything, from coffee covered in whipped cream to condiments and cookies.

16 Apr 2020

Novel high-speed microscope successfully records neural activities

Our brain contains tens of billions of nerve cells (neurons) which constantly communicate with each other by sending chemical and electrical flashes, each lasting a short one millisecond (0.001 sec). In every millisecond, these billions of swift-flying flashes altogether traveling in a giant star-map in the brain that lights up a tortuous glittering pattern.

15 Apr 2020

Largest proteomic study reveals link between glucose metabolism proteins and AD biology

In the largest study to date of proteins related to Alzheimer's disease, a team of researchers has identified disease-specific proteins and biological processes that could be developed into both new treatment targets and fluid biomarkers.

13 Apr 2020