Parkinson's Disease News and Research

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Parkinson's disease is a brain disorder. It occurs when certain nerve cells (neurons) in a part of the brain called the substantia nigra die or become impaired. When approximately 80 percent of neurons are damaged, the symptoms of Parkinson's disease appear. Parkinson's disease affects 1 in 100 people over the age of 60, with the average age of onset being 60 years. The risk of developing Parkinson's disease increases with age. In the United States, it is estimated that 60,000 new cases of Parkinson's disease are diagnosed each year, with 1.5 million Americans currently living with the disease.

Study: High levels of iron in the blood can prevent age-related damage

Genes linked to ageing that could help explain why some people age at different rates to others has been identified by scientists.

17 Jul 2020

Study: PINK1 and Parkin work together to induce selective autophagy

Researchers at TMIMS have revealed that PINK1 (a serine/threonine kinase) and Parkin (a ubiquitin ligating enzyme: E3) work together to ubiquitylate the outer membrane proteins of damaged mitochondria to induce selective autophagy called mitophagy.

10 Jul 2020

Salmonella biofilm protein can cause autoimmunity and arthritis in animals

Scientists from the Vaccine and Infectious Disease Organization-International Vaccine Centre at the University of Saskatchewan and Temple University have demonstrated that a Salmonella biofilm protein can cause autoimmune responses and arthritis in animals.

10 Jul 2020

Researchers identify osmotic stress as stimulator of cellular waste disposal

Cellular waste disposal, where autophagy and lysosomes interact, performs elementary functions, such as degrading damaged protein molecules, which impair cellular function, and reintroducing the resulting building blocks such as amino acids into the metabolic system.

29 Jun 2020

Novel silicon-based antioxidant agent may prevent kidney failure and Parkinson's disease

Oxidative stress is the result of reactive oxygen species (ROS) generation, and can be damaging to cells and tissues.

From Osaka University 19 Jun 2020

Solving A Parkinson's Disease Puzzle Through Protein Design

Dopamine is a neurotransmitter involved in everything and the receptors have been a longstanding target for treating disorders like Parkinson's disease.

17 Jun 2020

Disrupted circadian rhythms in older adults linked to increased risk of Parkinson's disease

Older men who have a weak or irregular circadian rhythm guiding their daily cycles of rest and activity are more likely to later develop Parkinson's disease, according to a new study by scientists at the UC San Francisco Weill Institute for Neurosciences who analyzed 11 years of data for nearly 3,000 independently living older men.

16 Jun 2020

Study reveals structure of an activated dopamine receptor

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells.

11 Jun 2020

'Fat burning' molecule holds promise for future treatment and prevention of obesity

Obesity affects more than 40 percent of adults in the United States and 13 percent of the global population.

9 Jun 2020

Research team discovers proteins that regulate interorganelle communication

Korea Brain Research Institute (KBRI headed by Suh Pann-ghill) announced on the 2nd that the joint research team of KBRI (team led by Dr. Mun Ji-young), Seoul National University, and Pohang University of Science and Technology discovered the proteins that engage in the formation of MAM, which is the cellular signaling hub.

4 Jun 2020

gnomAD Consortium releases first set of discoveries on human genetic variation

For the last eight years, the Genome Aggregation Database Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more than 125,000 exomes and 15,000 whole genomes from populations around the world.

29 May 2020