Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Researchers report the genome-wide atlas of chromatin-accessibility during stomatal development

Researchers at Nagoya University in Japan, the University of Texas at Austin, and the University of Washington have elucidated a mechanism that makes tiny plant stem cells destined to give rise to stomata, cellular valves of plants that facilitate global carbon cycles.

9 Feb 2023

Cochlear organoids provide a platform to understand sensorineural hearing loss

Disabling hearing loss affects one in every ten people and up to 25% of people over 60, according to the World Health Organization, and can have both genetic and environmental causes such as infections and noise exposure.

1 Feb 2023

Novel, more accurate computational tool for long-read RNA sequencing developed

On the journey from gene to protein, a nascent RNA molecule can be cut and joined, or spliced, in different ways before being translated into a protein.

31 Jan 2023

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two hallmarks of quality

The Stem Cell and Bone Marrow Transplant Program at Cedars-Sinai Cancer was recently recognized with two important hallmarks of quality: official accreditation for CAR T-cell therapy, and a third year in a row ranking among the top adult bone marrow transplant programs in the U.S.

31 Jan 2023

bit.bio partners with Automata to automate a key aspect of its production of iPSC derived human cells

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From Automata 26 Jan 2023

New computational tool for long-read RNA sequencing

An evolving RNA molecule can be cut and joined, or spliced, in various ways on the path from gene to protein before being translated into a protein. Using a technique called alternative splicing, multiple proteins can be encoded by a single gene.

24 Jan 2023

Blending multiple maps uncover new genetic causes of blindness

In a new study, Ran Elkon and Ruth Ashery-Padan of Tel Aviv University, Israel, and colleagues discovered a new genetic risk factor for adult-onset macular degeneration (AMD) by combining a map of gene regulatory sites with disease-associated loci.

18 Jan 2023

Grasping how a biological pathway causes stem cells to regenerate or die

According to a recent study conducted by Cedars-Sinai and the University of California, San Francisco (UCSF), altering a cellular process can cause stem cells, which are the cells that give rise to all other types of body cells, to either die or regenerate.

18 Jan 2023

Researchers study how cells use their sense of touch to make decisions during embryogenesis

Building tissues and organs is one of the most complex and important tasks that cells must accomplish during embryogenesis.

6 Jan 2023

The detrimental effects of alcohol consumption during pregnancy

For the first time, researchers at the University of Helsinki in Finland examined the effects of prenatal alcohol exposure on the epigenome and gene function of the placenta. The epigenome is a molecular coating on a DNA strand that controls how genes are expressed.

4 Jan 2023

New technique provides an unlimited supply of patient-derived tissues to study AMD

Scientists used patient stem cells and 3D bioprinting to produce eye tissue that will advance understanding of the mechanisms of blinding diseases.

3 Jan 2023

RXR: A key protein in the balanced production of different blood cells

In the regulation of hematopoietic stem cells—which are the immature stem cells that produce all the blood cell lineages—the cell protein retinoid X receptor (RXR) is an important element.

19 Dec 2022

Involvement of the piRNA pathway in brain plasticity and successful aging

The Neurobiology of miRNA team, headed by Davide De Pietri Tonelli of the Istituto Italiano di Tecnologia (IIT-Italian Institute of Technology), established a link between a family of small RNA molecules known as piRNAs and brain inflammation.

16 Dec 2022

Using CRISPR technology to reduce the symptoms of Huntington’s disease

A neurological condition called Huntington's disease (HD) results in a progressive decline in movement, coordination, and mental ability. It is brought on by a mutation in the huntingtin, or HTT, gene.

From UC San Diego 14 Dec 2022

Scientist honored for his contribution on ALS research

The Drs Ayeez and Shelena Lalji & Family ALS Endowed Award for Innovative Healing was given to Clive Svendsen, PhD, a pioneer in regenerative medicine, for his significant contributions to the field of amyotrophic lateral sclerosis (AL) at Massachusetts General Hospital’s Sean M. Healey & AMG Center for ALS.

12 Dec 2022

Molecular regulation underlying emergency hematopoiesis uncovered

If the body’s emergency hematopoiesis program activates, it signifies an alert state of the immune system and serves two functions: In comparison to “normal mode” hematopoiesis, the emergency program results in enhanced replacement of immune cells consumed during infections or inflammations.

12 Dec 2022

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022

UC San Diego Alpha Clinic awarded $8 million to bring new stem cell-based therapies to patients

Stem cells show particular promise in treating diseases for which few other effective treatments exist.

25 Nov 2022

Improving potential of cellular therapies with CAR T therapy

CAR T cells, or engineered immune cells, have demonstrated to the world the potential of customized immunotherapies to treat blood cancers. Researchers have just released highly encouraging preliminary data for CAR T therapy in a small group of lupus patients.

25 Nov 2022

Tankyrase protein plays an important role in helping drive bowel cancer

The inner workings of the main protein involved in an extensive range of cellular processes have been disclosed by researchers. This possibly sets the stage for improved and less toxic cancer drugs.

25 Nov 2022