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Fantastic Muscle Proteins And Where To Find Them

Researchers at MDC developed a mouse model that enables them to look inside a working muscle and identify the proteins that allow the sarcomere to contract.

22 Jun 2020

Inhibitory interneurons excite the developing brain, study finds

Brain function depends on inhibitory cells that balance or 'brake' excitation. These neurons allow the brain to process information and also prevent runaway seizures.

15 Jun 2020

Deleting a key gene to create an immune cell with stronger anti-tumor activity

Using induced pluripotent stem cells (iPSCs) and deleting a key gene, researchers at University of California San Diego School of Medicine have created natural killer cells -- a type of immune cell -- with measurably stronger activity against a form of leukemia, both in vivo and in vitro.

From UC San Diego 12 Jun 2020

Intron detention is integral to post-transcriptional regulation mechanism

Muscle stem cells are the reserve stem cells found in skeletal muscles. They play a crucial role in muscle repair following damage.

11 Jun 2020

Exploring the cradle of hematopoietic stem cells

Researchers from the group of Catherine Robin at the Hubrecht Institute characterized the molecular landscape of the aorta that supports the generation of the first Hematopoietic Stem Cells (HSCs) in the embryo.

5 Jun 2020

Researchers deconstruct complex mechanisms that control tissue repair

ETH researchers have deconstructed the mechanisms that control wound healing and scar formation in more detail.

4 Jun 2020

A remote optical stimulation for neural cells

A team led by researchers at Carnegie Mellon University has created a new technology that enhances scientists' ability to communicate with neural cells using light.

2 Jun 2020

Research identifies how neuronal transmission is disrupted in ALS

Patients with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, lose muscle control as nerve cells or neurons in the brain and spinal cord degenerate and can no longer send signals to muscles.

29 May 2020

Study identifies potent neutralizing antibodies against SARS-CoV-2

A joint research team led by Sunney Xie, Director of Beijing Advanced Innovation Center for Genomics at Peking University has successfully identified multiple highly potent neutralizing antibodies against the novel coronavirus SARS-CoV-2, the causative virus of the respiratory disease COVID-19, from convalescent plasma by high-throughput single-cell sequencing.

29 May 2020

Researchers design antibody to identify pathogens of Alzheimer's disease

Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.

26 May 2020

Gene associated with thinness may play a role in resisting weight gain

Some people can remain slim easily, irrespective of their diet, while others might be dieting and working out at the gym to maintain their shape.

25 May 2020

Biochemical and computational methods for large-scale protein-arginine methylation analysis

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs).

23 May 2020

Scientists develop novel model of liver cancer stem cells from normal iPSCs

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma.

22 May 2020

Cell-culture based in vitro test systems for screening of antitumor drugs

As we know, a malignant tumor is a complex system of mutated cells which constantly interacts with and involves healthy cells in the body.

21 May 2020

Innovative two-photon microscopy enables in vivo subcellular imaging of the retina

Retina is the only part of the central nervous system that can be visualized noninvasively with optical imaging approaches.

21 May 2020

Texas A&M lab produces 3D-bioprinted bone tissues

Dr. Akhilesh K. Gaharwar, associate professor, has developed a highly printable bioink as a platform to generate anatomical-scale functional tissues. This study was recently published in the American Chemical Society's Applied Materials and Interfaces.

20 May 2020

New head-mounted microscope allows access to inner workings of the brain

Scientists working at caesar have developed a small head-mounted microscope that allows access to the inner workings of the brain.

20 May 2020

Direct Control Of Dendritic Cells For Tracking And Immune Modulation

Dendritic cells are one of our bodies' first line of defense and are stationed like sentinels at all surfaces, as well as in most of our organs.

19 May 2020

Computational methods can help design protein-based vaccines

Vaccines are regarded as an effective intervention to stop the spread of infectious diseases. They produce antibodies by activating the immune system.

18 May 2020

Mice study identifies protein vital for liver restoration and regeneration after hepatic surgery

Researchers from the Faculty of Medicine of the University of Barcelona and the CELLEX Biomedical Research Centre from IDIBAPS have identified in a study with mice a protein which is fundamental to guarantee the restoration and regeneration of the liver after a transplant or hepatic surgery.

12 May 2020