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Metabolite of dietary soy may decrease key risk factor for dementia

A metabolite produced following consumption of dietary soy may decrease a key risk factor for dementia--with the help of the right bacteria, according to a new discovery led by researchers at the University of Pittsburgh Graduate School of Public Health.

23 Oct 2020

Study sheds light on whether corals are genetically equipped to handle warmer oceans

In 1998, ocean temperatures soared, and the world experienced its first significant coral bleaching event. From the Great Barrier Reef to Indonesia to Central America, corals turned white and ghostly.

15 Oct 2020

Scientists develop new antimicrobial molecules from toxic proteins in wasp venom

A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has engineered powerful new antimicrobial molecules from toxic proteins found in wasp venom.

13 Oct 2020

Gene variations that regulate dopamine levels may influence the mobility of elders

Variations in a gene that regulates dopamine levels in the brain may influence the mobility of elderly and frail adults, according to new research from the University of Pittsburgh Graduate School of Public Health.

13 Oct 2020

T-cell-based vaccine strategy provides broader protection against influenza

As Americans begin pulling up their sleeves for an annual flu vaccine, researchers at the University of Wisconsin-Madison have provided new insights into an alternative vaccine approach that provides broader protection against seasonal influenza.

24 Sep 2020

New Dual CAR T cell immunotherapy can help fight against HIV infection

A recent study published in the journal Nature Medicine, led by researchers James Riley, PhD, a professor of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, and Todd Allen, PhD, a professor of Medicine at Harvard Medical School and Group Leader at the Ragon Institute of MGH, MIT and Harvard, describes a new Dual CAR T cell immunotherapy that can help fight HIV infection

24 Sep 2020

How Artificial Intelligence aids Gene Activation Discovery

Professor James Kadonaga speaks to AZoLifeSciences about his research into gene activation, and how artificial intelligence can help to aid its discovery.

From UC San Diego 18 Sep 2020

Bioengineers detect the presence of maxRNA on the surface of human cells

Bioengineers have demonstrated that RNA produced by the human genome is found on the surface of human cells.

11 Sep 2020

Researchers investigate cellular factors that could be significant for COVID-19 infection

An infection with the coronavirus SARS-CoV-2 can affect multiple organs. With this in mind, researchers of the German Center for Neurodegenerative Diseases (DZNE) and Cornell University in the US have investigated cellular factors that could be significant for an infection.

4 Sep 2020

Re-designed natural enzyme shows promise in promoting the regrowth of nerve tissue injury

A team of researchers from University of Toronto Engineering and the University of Michigan has redesigned and enhanced a natural enzyme that shows promise in promoting the regrowth of nerve tissue following injury.

From University of Toronto 25 Aug 2020

Novel gene editing approach removes latent herpes simplex virus 1

Infectious disease researchers at Fred Hutchinson Cancer Research Center have used a gene editing approach to remove latent herpes simplex virus 1, or HSV-1, also known as oral herpes.

19 Aug 2020

COVID-19 Prevention Network announces two trials to evaluate monoclonal antibodies

The COVID-19 Prevention Network (CoVPN) today announced two Phase 3 trials to determine whether monoclonal antibodies (mAbs) can prevent SARS-CoV-2, the virus that causes COVID-19.

11 Aug 2020

New method targets hidden HIV viral reservoirs during antiretroviral therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

10 Aug 2020

NIH clinical study to evaluate potential new therapeutics for mild, moderate COVID-19

A Phase 2 clinical trial will evaluate the safety and efficacy of potential new therapeutics for COVID-19, including an investigational therapeutic based on synthetic monoclonal antibodies (mAbs) to treat the disease.

5 Aug 2020

Cholesterol-lowering medication improves function of the coronary arteries

In a pilot study of people living with HIV or high levels of cholesterol, Johns Hopkins Medicine researchers found that a six-week course of a cholesterol-lowering medication improved the function of the coronary arteries that provide oxygen to the heart.

30 Jul 2020

Multiomics analysis reveals multiple characteristics of HIV-1-producing cells in vivo

For eradication of HIV-1 infection, it is important to elucidate the detailed features and heterogeneity of HIV-1-infected cells in vivo.

29 Jul 2020

NIH establishes clinical trial network to test vaccines and monoclonal antibodies for COVID-19

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has established a new clinical trial network that aims to enroll thousands of volunteers in large-scale clinical trials testing a variety of investigational vaccines and monoclonal antibodies intended to protect people from COVID-19.

14 Jul 2020

Modeling research shows increase in HIV, TB, and malaria deaths due to COVID-19 pandemic

But there is still an opportunity to substantially reduce the death toll by prioritizing the most critical services, specifically antiretroviral therapy for HIV, timely TB diagnosis and treatment, and provision of long-lasting insecticide-treated nets for malaria, researchers say.

14 Jul 2020

Integrating metabolomics and genomics to improve patient diagnosis

A patient and family walk into a doctor's office. They hope that the latest tests will reveal what is causing the patient's illness and end the diagnostic odyssey they have been going through for years.

8 Jul 2020

Study shows promise for developing novel COVID-19 therapeutics

A protein known as polymerase is used by SARS-CoV-2—the coronavirus that is responsible for causing the worldwide COVID-19 pandemic—to replicate its genome within the infected human cells.

1 Jul 2020