Acute Myeloid Leukemia News and Research

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Acute Myeloid Leukemia (AML) is a rapidly progressing cancer of the blood characterized by the uncontrolled proliferation of immature blast cells in the bone marrow. The Leukemia and Lymphoma Society estimates that over 13,000 new cases of AML were diagnosed and approximately 9,000 deaths from AML occurred in the U.S. during 2007. AML is generally a disease of older adults, and the median age of a patient diagnosed with AML is about 67 years. A majority of elderly patients are not considered candidates for standard induction therapy or decline therapy, resulting in an acute need for new treatment options.
CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

CloneTracer Reveals a Differentiation Landscape of Acute Myeloid Leukemia

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

New Epigenetic Vulnerability Of Acute Myeloid Leukemia Revealed

Previously unknown telomere and cancer connection to the immune system revealed

Previously unknown telomere and cancer connection to the immune system revealed

Potential therapeutic can synergize with existing drugs to effectively destroy leukemia cells

Potential therapeutic can synergize with existing drugs to effectively destroy leukemia cells

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Study pinpoints a splicing deregulation that causes therapeutic vulnerability in pediatric AML

Reversal of ADAR1 hyper-editing with small molecule inhibitor

Reversal of ADAR1 hyper-editing with small molecule inhibitor

Novel combination therapy shows promise in acute myeloid leukemia

Novel combination therapy shows promise in acute myeloid leukemia

Revealing the functional significance of DDX41 in great detail

Revealing the functional significance of DDX41 in great detail

Spaceflight increases the risk of developing cancer and heart disease

Spaceflight increases the risk of developing cancer and heart disease

Rewiring the inner workings of leukemia cells to reverse drug resistance

Rewiring the inner workings of leukemia cells to reverse drug resistance

Study highlights the role of genetic “bridge” in leukemia development

Study highlights the role of genetic “bridge” in leukemia development

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Two distinct classes of stem cells drive treatment resistance in patients with myelodysplastic syndromes

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

Experts trigger apoptosis in leukemia cells by disrupting their energy maintenance mechanism

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

New proteomics method identifies proteins responsible for regulating R-loop levels in human cells

CSHL researchers spotlight the role of a previously little-known protein in leukemia

CSHL researchers spotlight the role of a previously little-known protein in leukemia

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

UD biochemist explores how mRNA eraser enzymes work in our cells

UD biochemist explores how mRNA eraser enzymes work in our cells

New approach to cut off cancer cells’ food supply and kill them

New approach to cut off cancer cells’ food supply and kill them

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Study pinpoints means to restore the efficacy of drugs for acute myeloid leukemia

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients

Genetic and molecular mechanisms make chemotherapy drug work for some cancer patients