Adolescents News and Research

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Study shows how genes help control appetite and obesity in children

Have you ever noticed why little newborns gain weight at varying rates and in varying amounts during their early years of life?

23 Mar 2022

Research highlights the impact of genes and environment on human health

The Healthy Nevada Project® has discovered links between genetics, obesity, and childhood trauma, connecting socioeconomic health factors, genetics, and disease.

11 Mar 2022

US research reveals the role of Heparan Sulfate in obesity

AMSBIO reports how researchers at the Washington University School of Medicine (St. Louis, USA) have used their 10E4 Heparan Sulfate (HS) antibody in pioneering obesity research to quantify the role of HS in the process of intercellular mitochondria transfer to macrophages.

From AMS Biotechnology 1 Mar 2022

CHOP-led network aims to unlock the genetic mysteries behind pediatric brain tumors

Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia.

3 Nov 2021

Healthy diet improves weight and reduces cardiovascular disease risks in overweight children

A Cleveland Clinic-led research team found that statistically overweight children who followed a healthy eating pattern significantly improved weight and reduced a variety of cardiovascular disease risks.

22 Sep 2021

Study finds spike in calories among children, adolescents due to consumption of ultraprocessed foods

The calories that children and adolescents consumed from ultraprocessed foods jumped from 61% to 67% of total caloric intake from 1999 to 2018, according to a new study from researchers at the Friedman School of Nutrition Science & Policy at Tufts University.

12 Aug 2021

New insights on how synovial sarcoma develops and spreads

A new study published today in Cancer Discovery, a journal of the American Association for Cancer Research, reports findings that may change the understanding of how synovial sarcoma develops and spreads.

7 Jun 2021

Adolescents with higher omega-3 levels in blood are less likely to acquire psychotic illness

Adolescents who had greater levels of an omega-3 fatty acid in their blood were less likely to acquire psychotic illness in early adulthood.

3 Jun 2021

Understanding molecular determinants of liver cancer in patients with Indigenous American ancestry

Oncotarget published "Global DNA hypermethylation pattern and unique gene expression signature in liver cancer from patients with Indigenous American ancestry" which reported that contrasting with this pattern, the age structure of HCC in Andean people displays a bimodal distribution with half of the patients developing HCC in adolescence and early adulthood.

2 Jun 2021

TV marketing lures vulnerable soft drinks consumers, study finds

What keeps consumers hooked on high sugar soft drink? Advertising, of course. But why are some consumers more adept at ignoring these cues than others?

1 Jun 2021

Genetically engineered immune cells deliver anticancer signal to organs to prevent metastasis

Scientists have genetically engineered immune cells, called myeloid cells, to precisely deliver an anticancer signal to organs where cancer may spread.

From National Cancer Institute (NCI) 25 Mar 2021

Nutritional supplement may reduce the risk of strokes caused by a rare genetic disorder

Researchers from Children's Hospital of Philadelphia (CHOP) have discovered that a widely used nutritional supplement may significantly reduce the risk of fatal strokes caused by a rare genetic disorder.

24 Mar 2021

Scientists provide a complete phenotypic landscape of SCN2A-related disorders

Researchers from Children's Hospital of Philadelphia (CHOP) affiliated with the CHOP Epilepsy Neurogenetics Initiative (ENGIN) have compiled a complete genetic and clinical analysis of more than 400 individuals with SCN2A-related disorder, which has been linked to a variety of neurodevelopmental disorders, including epilepsy and autism.

18 Mar 2021

Engineered safety switch reduces CAR-T immunotherapy-related side effects

UNC Lineberger Comprehensive Cancer Center researchers have successfully used an experimental safety switch, incorporated as part of a chimeric antigen receptor T-cell (CAR-T) therapy, a type of immunotherapy, to reduce the severity of treatment side effects that sometimes occur.

5 Mar 2021

Researchers find effective combination of therapies for managing mitochondrial disease

Researchers have demonstrated how one combination of therapies may be beneficial for patients with mitochondrial respiratory chain disorders.

3 Mar 2021

Longitudinal study identifies many genetic markers linked to bone mineral accrual

A multidisciplinary team of researchers led by Children's Hospital of Philadelphia has discovered several genetic markers associated with bone mineral accrual, which could ultimately help identify causes of eventual osteoporosis earlier in life through genetic testing.

7 Jan 2021

Researchers find genetic correlations between inflammatory bowel disease and stress, depression

Using sophisticated 3D genomic mapping and integrating with public data resulting from genome-wide association studies (GWAS), researchers at Children's Hospital of Philadelphia (CHOP) have found significant genetic correlations between inflammatory bowel disease (IBD) and stress and depression.

30 Oct 2020

Cell nucleus may enable the cells to evade crowded environments

Like people, cells in the human body protect their personal space. They seem to know how much space they need, and if it gets too tight, most cells prefer to break free.

20 Oct 2020

Climate change-driven wildfires cause devastating health impacts

Immediate actions are needed to limit the greenhouse gas emissions that are driving climate change that helps fuel wildfires, a Monash University study says.

14 Oct 2020

New index relies on pigs to demonstrate protein quality for humans

Nearly a decade ago, the UN's Food and Agriculture Organization (FAO) developed a new index to assess protein quality in foods. The goal, writ large, was to address food security for the world's most vulnerable populations, creating more accurate tools for food assistance programs seeking to provide balanced nutrition.

24 Sep 2020