Antibiotics are drugs used to treat infections caused by bacteria and other microorganisms.
Conjunctival Goblet Cells (CGCs) are specialized epithelial cells that secrete mucins to generate the tear film’s mucus layer.
Most antibiotics are double-edged swords. Besides killing the pathogen they are prescribed for, they also decimate beneficial bacteria and change the composition of the gut microbiome.
According to biomedical engineers at Duke University, the physical mechanism that enables high doses of antibiotics to encourage the transmission of antibiotic resistance across bacteria is now identified.
A study team developed an early-stage therapy that sabotages the pump and restores antibiotic efficiency by disclosing the structure of a protein needed by bacteria to pump out antibiotics.
Two recent research have shown a completely new perspective of how bacterial cells repair broken parts of their DNA (lesions).
Chronic skin wounds are a rising global issue among the elderly, individuals with severe burns, and people with underlying medical diseases such as diabetes.
Why do genetically similar cells react to the same extrinsic stimuli, such as antibiotics, in such diverse ways?
RNA switches (also known as riboswitches) control which genes are turned “on” and “off”, much like a light switch. Although this appears to be a straightforward process, biologists have been astonished by the inner workings of these switches for decades.
They have devised a novel means of delivering medicines and peptides into cells.
A team led by Karolinska Institute used AI and structural biology to learn more about two similar proteins that protect against bacterial infection in the urinary tract.
All life evolves: microorganisms can become resistant to drugs, viruses evade our vaccines, and species may adapt to climate change.
The spectacular structure of the protective armor of superbug C.difficile has been revealed for the first time showing the close-knit yet flexible outer layer – like chain mail.
Chemists at MIT have developed a novel way to synthesize himastatin, a natural compound that has shown potential as an antibiotic.
A recent study proves that antibiotic use in the first week of birth is associated with a reduction in the number of healthy bacteria required to digest milk.
Genetic mutations help certain people succeed in the face of natural selection.
A*STAR’s GIS and ID Labs have discovered KCNJ15, a gene linked to the human immune system’s ability to combat TB and maybe other infectious diseases.
Northwestern University synthetic biologists have developed a low-cost, easy-to-use, hand-held device that can let users know -; within mere minutes -; if their water is safe to drink.
Estonian Microbiome Project, using electronic health data from more than 2500 biobank participants finds long-term antibiotic usage, independent from recent administration, has an impact on the microbiome, partly explaining the common bacterial signatures overlapping between diseases.
A signaling mechanism that enables bacteria like Salmonella to escape destruction by the immune system of the host was discovered by scientists.
The solutions to many of humanity's problems can be found within nature. For instance, who could have guessed that an antibiotic as powerful as penicillin would be found in a common mold, or that the drug aspirin would be derived from the bark of the willow tree?