Apoptosis is programmed cell death, the body's normal method of disposing of damaged, unwanted, or unneeded cells.
Green tea contains an antioxidant that may boost the concentrations of p53, called the “guardian of the genome,” for its potential to kill cancerous cells.
T lymphocytes, or T cells, are an important component of our immune system. They can recognize foreign proteins, so-called antigens, as peptide fragments - for instance, those derived from viruses or cancer cells.
A new study shows that proteins called IAPs, which can trigger programmed cell death, are inhibited by a specific chemical modification, and reveals that they play a wider role in protein quality control than previously assumed.
Researchers at Baylor College of Medicine have discovered how therapeutics targeting RNA splicing can activate antiviral immune pathways in triple negative breast cancers (TNBC) to trigger tumor cell death and signal the body's immune response.
A key way radiation therapy and chemotherapy work is by making highly lethal double-strand breaks in the DNA of cancer cells.
Within a single cell, more than a quarter of all proteins are found in the membrane, in which they carry out crucial functions.
Pyroptosis is a highly inflammatory form of programmed necrotic cell death that acts as a defense mechanism against the infection of bacterial and viral pathogens. Pyroptosis is executed by gasdermin, a family of pore-forming proteins.
Researchers have investigated the role of the interplays within the proteins membranes of viral families involved in the control of programmed cell death.
Using machine learning and gene sequencing, scientists from New York University have designed a “developmental atlas” of gene expression in neurons to classify over 250,000 neurons in the brains of fruit flies.
A paper recently uploaded to bioRxiv* aimed to utilize genome-wide CRISPR screening to identify genes involved in modulating the activity of COVID-19 drugs.
A new study by researchers from the Medical University of Vienna could prove beneficial for the human immune system.
In their quest to destroy cancer cells, researchers are turning to combinational therapies more and more. Scientists from Germany and China have now combined a chemotherapeutic and photodynamic approach.
Mice study has revealed a formerly unknown interaction between an immune cell protein and molecules extracted from dietary fiber.
When Goping’s research team found that a protein was linked to poor outcomes in breast cancer patients, she wanted to find out the reason behind this.
Enteric pathogens, such as the bacterium Shigella, can cause severe intestinal disease with bloody diarrhea. In a new study, researchers from Tokyo Medical and Dental University (TMDU) discovered a novel molecular survival strategy by which Shigella is able to cause damage to the intestines despite two elaborate protective mechanisms used by host cells.
Researchers have discovered that when DNA in the moss Physcomitrella patens is damaged, it causes cells to reprogram on their own to change into stem cells.
Monash Biomedicine Discovery Institute scientists have discovered a previously unknown method used by bacteria to evade immune responses.
AZoLifeSciences speaks to Dr. James Whittle and Professor Geoff Lindeman about their research in enhancing breast cancer therapy through killing sleeper cells.
When our neurons -- the principle cells of the brain -- die, so do we. Most neurons are created during embryonic development and have no "backup" after birth.
The cover for issue 29 of Oncotarget features Figure 5, "In vivo effects of treatment with L-Grb2 in combination with anti-angiogenic therapy in an ovarian tumor model," by Lara, et al. which reported that adaptor proteins such as growth factor receptor-bound protein-2 play important roles in cancer cell signaling.