Many people start to feel pain and stiffness in their bodies over time. Sometimes their hands or knees or shoulders get sore and are hard to move and may become swollen. These people may have arthritis. Arthritis may be caused by inflammation of the tissue lining the joints. Some signs of inflammation include redness, heat, pain, and swelling. These problems are telling you that something is wrong. Joints are places where two bones meet, such as your elbow or knee. Over time, in some types of arthritis but not in all, the joints involved can become severely damaged. There are different types of arthritis. In some diseases in which arthritis occurs, other organs, such as your eyes, your chest, or your skin, can also be affected. Some people may worry that arthritis means they won’t be able to work or take care of their children and their family. Others think that you just have to accept things like arthritis.
With age, cells can experience senescence, a state where they stop growing but continue releasing inflammatory and tissue-degrading molecules.
The path from mitochondrial stress to leaking endosomes to immune system initiation in mouse cells is outlined by Salk scientists, providing new therapeutic targets to potentially reduce inflammation in aging and disease.
A pair of proteins, YAP and TAZ, has been identified as conductors of bone development in the womb and could provide insight into genetic diseases such as osteogenesis imperfecta, known commonly as "brittle bone disease."
Researchers at the Icahn School of Medicine at Mount Sinai have gained a deeper understanding of the nuanced roles of JAK inhibitors, or modulators, in inflammation across various cell types and tissues.
Former CEO and Chairman of Google Eric Schmidt, and Ken Griffin, founder and CEO of Citadel and founder of Griffin Catalyst, are today (Monday 30 October) being announced as the first members of a new consortium that will shape the future of the best-in-class UK Biobank.
A new study from the USC Michelson Center for Convergent Bioscience’s Bridge Institute, in partnership with multinational teams from India, Australia, and Switzerland, sheds insight on these proteins.
Throughout a person’s life, many stimuli can turn on and off many of the genes, resulting in the variances that distinguish people.
University of Rochester scientists have successfully transmitted a longevity gene from naked mole rats to mice, resulting in better health and an extension of the mouse’s lifespan.
Using artificial intelligence to analyze tens of thousands of X-ray images and genetic sequences, researchers from The University of Texas at Austin and New York Genome Center have been able to pinpoint the genes that shape our skeletons, from the width of our shoulders to the length of our legs.
Two anti-inflammatory drugs, abatacept and infliximab, reduced deaths among patients hospitalized with severe COVID-19, according to a national study led by Washington University School of Medicine in St. Louis.
While the exterior features of a woman can alter throughout pregnancy, scientists are surprisingly ignorant about the interior biological changes that take place.
Conditions like ulcerative colitis and Crohn's disease, which cause inflammation in the body, can be identified or tracked by measuring a protein called calprotectin.
Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.
Neuropathy is a type of chronic pain triggered by nerve injury or certain diseases. It affects millions of people worldwide, significantly deteriorating their quality of life.
A new study has identified potential broad-spectrum antiviral agents that can target multiple families of RNA viruses that continue to pose a significant threat for future pandemics.
People with dementia have protein build-up in astrocytes that may trigger abnormal antiviral activity and memory loss, according to a preclinical study by a team of Weill Cornell Medicine investigators.
Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.
The fruit of the cocklebur plant, which grows worldwide and is often considered a noxious weed, has antioxidant and anti-inflammatory components that could make it useful as a skin protectant, according to new research.
Certain microbes are considered to play a role in the development of inflammatory disorders such as inflammatory bowel disease (IBD).
A Michigan Medicine study has identified a new potential target for treating osteoarthritis – a debilitating joint disease that affects over 31 million Americans and is a leading cause of disability worldwide.