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Probiotic application shown to promote health and growth of piglets

This study is led by Prof. Heping Zhang (Inner Mongolia Key Laboratory of Dairy Biotechnology and Engineering, Inner Mongolia Agricultural University).

20 Feb 2023

Extended generation of blood cells in wild-type animals from pluripotent stem cells

Cells present in the blood like red blood cells, immune cells, and other crucial cell types are renewed continually from stem cells, the alleged hematopoietic stem and progenitor cells (HSPCs).

17 Feb 2023

High diversity in T-cell receptor genes explains diverse response to infections

Researchers from Karolinska Institutet have demonstrated that the genes that encode the T cell receptors change significantly between individuals and communities, which could help explain why people react differently to certain diseases.

17 Feb 2023

Developing a potential drug molecule that targets STAT5

STAT5 has generally been recognized as an enticing cancer target, but after years of research, it was downgraded to the “undruggable” category. Now, scientists at the University of Michigan Rogel Cancer Center have achieved success with a novel approach.

17 Feb 2023

Reversal of ADAR1 hyper-editing with small molecule inhibitor

Researchers at University of California San Diego School of Medicine, Sanford Stem Cell Institute and Moores Cancer Center report that a late-stage, pre-clinical small molecule inhibitor, called rebecsinib, reverses malignant hyper-editing by an inflammation-induced protein isoform, known as ADAR1 p150.

17 Feb 2023

New insights into genetics of sexually dimorphic fat distribution in humans

Obesity causes many health problems and worsens several chronic illnesses, including type 2 diabetes and cardiovascular disease, however, some obese people are more susceptible to complications than others.

17 Feb 2023

B lymphocytes stimulate the in-demand production of innate immune cells during infection

An SOS signals a call for immediate action during an emergency to request a need for protection. The immune system, a network of defense mechanisms, enhances protection to recover the body's internal stability.

16 Feb 2023

PFAS chemical helps suppress the neutrophil respiratory burst, study finds

In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst – the method white blood cells known as neutrophils use to kill invading pathogens.

16 Feb 2023

Researchers construct the first chromosome-scale reference genome of Plantago ovata

Scientists have for the first time constructed the reference genome for the source of the popular fiber supplement, psyllium husk, which could boost supplies of the versatile plant-derived product.

16 Feb 2023

The essential protein needed for immune evasion and tumor cell metabolism

Typically, tumor cells change their energy metabolism and take in more glucose to enable their rapid division and spread. As a result, the body’s immune response to cancer is suppressed by limiting the immune cells’ access to glucose.

15 Feb 2023

Pungent ginger constituent puts white blood cells on heightened alert

Ginger has a reputation for stimulating the immune system. New results from the Leibniz Institute for Food Systems Biology at the Technical University of Munich (Leibniz-LSB@TUM) now support this thesis.

15 Feb 2023

Study reveals important role of Secretin receptor in regulating drinking behavior under thirst

Animals instinctively find and consume water when feeling thirsty in order to restore body fluid osmolality and plasma volume to their set points.

15 Feb 2023

Inhibiting astrocyte hyperactivity can reverse cognitive deficits associated with social deprivation

Here is an important reason to stay in touch with friends and family: social isolation causes memory and learning deficits and other behavioral changes.

15 Feb 2023

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

The University of Texas MD Anderson Cancer Center and Replay today announced the launch of Syena, a new oncology-focused product company pioneering T cell receptor (TCR) natural killer (NK) cell therapies.

15 Feb 2023

Lung immunity in neonates is influenced by the mother’s microbiota

A recent study led by Bruno Silva Santos, Group Leader and Vice-Director at the Instituto de Medicina Molecular João Lobo Antunes, found that a specific subset of white blood cells called γδ T cells affects the transfer of the mother’s microbiota during childbirth and breastfeeding and affects the infants’ lung immune response.

15 Feb 2023

Analyzing the immune microenvironment around Hodgkin lymphoma tumors

The most detailed study of Hodgkin lymphoma, a type of blood cancer, has offered considerable insight into what tumor cells must do to sustain. The Wellcome Sanger Institute discovered that cancer cells utilize signals to attract specific types of immune cells and direct them not to attack.

15 Feb 2023

Study charts seasonal and circadian genetic variation across the human body

The daily rotation of Earth and its yearly voyage around the Sun marks the natural rhythm of life on the planet.

14 Feb 2023

Study explains why cancers stop responding to kinase inhibitors and come back stronger

More than 70 FDA-approved cancer drugs are kinase inhibitors, which work by blocking kinases-;enzymes that add phosphate groups to molecules in the cell-;and preventing the chemical activity necessary for signaling and growth in cancer cells.

14 Feb 2023

Research provides insight into the regulation of heartbeats

UT Southwestern Medical Center researchers have mapped gene control elements in specialized cardiac cells responsible for coordinating heartbeats. The findings of the genome exploration study, published in The Journal of Clinical Investigation, provide insight into how heartbeats are regulated and could impact diagnosis and risk prediction for a variety of common arrhythmias.

14 Feb 2023

New software helps identify genes that play vital roles in the development

Computer software developed at Washington University School of Medicine in St. Louis can predict what happens to complex gene networks when individual genes are missing or dialed up more than usual.

14 Feb 2023

Blood News and Research

Probiotic application shown to promote health and growth of piglets

Extended generation of blood cells in wild-type animals from pluripotent stem cells

High diversity in T-cell receptor genes explains diverse response to infections

Developing a potential drug molecule that targets STAT5

Reversal of ADAR1 hyper-editing with small molecule inhibitor

New insights into genetics of sexually dimorphic fat distribution in humans

B lymphocytes stimulate the in-demand production of innate immune cells during infection

PFAS chemical helps suppress the neutrophil respiratory burst, study finds

Researchers construct the first chromosome-scale reference genome of Plantago ovata

The essential protein needed for immune evasion and tumor cell metabolism

Pungent ginger constituent puts white blood cells on heightened alert

Study reveals important role of Secretin receptor in regulating drinking behavior under thirst

Inhibiting astrocyte hyperactivity can reverse cognitive deficits associated with social deprivation

MD Anderson and Replay launch new company pioneering T cell receptor NK cell therapies

Lung immunity in neonates is influenced by the mother’s microbiota

Analyzing the immune microenvironment around Hodgkin lymphoma tumors

Study charts seasonal and circadian genetic variation across the human body

Study explains why cancers stop responding to kinase inhibitors and come back stronger

Research provides insight into the regulation of heartbeats

New software helps identify genes that play vital roles in the development

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