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Unraveling the Complexities of X Chromosome Inheritance

A new study published in Nature Genetics by the Lymphoid Development Group at the MRC Laboratory of Medical Sciences has reveals that the contribution of cells expressing maternal or paternal X chromosomes can be selectively skewed in different parts of the body.

26 Jul 2024

New Insights into the Mechanisms of Gene Misbehavior

Researchers have discovered that a startlingly widespread occurrence in the healthy human population is "gene misbehavior," or the state in which genes are active when they should be inactive.

25 Jul 2024

Study Reveals Titin Mutation Effects on Cardiac Development and Atrial Fibrillation

Millions of adults have atrial fibrillation -; an irregular beating of the upper chambers of the heart that yields increased risk of heart failure, stroke and death.

25 Jul 2024

Study Shows the Ability of Protein 'Signatures' to Predict Onset of 67 Diseases

Research on thousands of proteins measured from a drop of blood demonstrates the ability of proteins to predict the onset of many diverse diseases.

24 Jul 2024

Machine Learning and Infrared Light Unlock Health Insights

Researchers at Ludwig-Maximilians-Universität München (LMU) and the Max Planck Institute of Quantum Optics (MPQ), in collaboration with Helmholtz Zentrum München, are pioneering a new approach to health screening.

22 Jul 2024

New Model Reveals Interplay Between Circadian Rhythms and Sleep-Wake Cycles in Gene Expression

A mathematical, driven, damped harmonic oscillator model to assess the varying contributions of circadian cues and sleep-wake processes on gene expression and the rhythmic transcriptome.

18 Jul 2024

How an obesity gene influences brain function

A complex condition, obesity is brought on by a confluence of factors including behavior, diet, and heredity. Getting enough food to survive and thrive was a challenge for millennia.

16 Jul 2024

New Insights into the Composition and Efficacy of Stem Cell Therapies

Two commonly used stem cell therapies are found to contain entirely different types of cells, despite their frequent interchange, according to research from the University of California San Diego.

15 Jul 2024

Liver-on-Chips: Innovations, Applications, and Challenges in Drug Development

The development and application of liver-on-chips and the factors preventing its widespread use in drug discovery.

12 Jul 2024

Liver Blood Vessels Trigger 'Sleep Timer' to Inactivate Immune Cells in Chronic Hepatitis B

In chronic hepatitis B, the liver contains immune cells that could destroy hepatitis B virus infected cells but are inactive.

11 Jul 2024

Phage-Derived Endolysin Offers Targeted Treatment for Dysbiosis-Driven Acute GVHD

Allogenic hematopoietic cell transplantation (allo-HCT) involves transferring healthy donor stem cells to recipients with conditions like blood cancer, bone marrow failure, or certain genetic blood disorders.

11 Jul 2024

New Insights into ILC2 Development Could Lead to Innovative Therapies for Allergic Diseases

Scientists have discovered a novel mechanism of ILC2 immune cell development which may be involved in exacerbating allergic diseases.

11 Jul 2024

Unveiling the Power of mRNA and LNPs in Modern Medicine

Consider a situation in which an expert hacker has to upload vital software to update a central server and stop a potentially fatal virus from causing havoc on a sizable computer network.

10 Jul 2024

Exploring Gut Microbiome Modulation for Disease Prevention

Carriers of gut Blastocystis, a single-celled organism that has been classified as either a parasite or harmless organism but is frequently found in the digestive system, were associated with markers of good cardiovascular health and decreased body fat in an analysis of over 50,000 people from around the world.

9 Jul 2024

3D-Printed Device Transforms Blood Conductivity Measurement with AI Precision

A novel lab-on-a-chip device consisting of a portable millifluidic nanogenerator that can gauge blood conductivity at low frequency.

9 Jul 2024

Comprehensive Analysis Identifies Risk Factors for Multiple Cancers

Scientists have discovered over 5,000 genetic variations that give rise to specific cancers, along with a possible therapeutic target that could be used to treat or even stop these cancers from growing.

8 Jul 2024

Scientists develop first fully functional human immune system in mouse model

Researchers at The University of Texas Health Science Center in San Antonio have produced a mouse model that is humanized, complete with a human immune system and a gut microbiome that resembles that of a human being and is able to elicit particular antibody responses.

8 Jul 2024