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New Insights Into How Genetic Variants Impact Gene Expression

The Department of Biomedical Informatics (DBMI) at the University of Colorado School of Medicine, in collaboration with the University of California San Francisco and Stanford University, has recently published a study that is the largest of its kind to focus on ancestry correlations with biomedical traits.

26 May 2023

Study Characterizes the Properties of MAIT Cells in Mouse Lung

A population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike.

26 May 2023

Fructose is Needed for Enhanced Egg Production in Fruit Flies, Study Reveals

To many people, the sugars we eat may seem like a luxury that can do more harm than good. But now, researchers from Japan have discovered that in insects, dietary sugars play a key role in reproduction.

25 May 2023

Ex Vivo Expansion of HSCs Using a Novel Culture System

Hematopoietic stem cells (HSCs) are immature blood cells found in the bone marrow that can be stimulated to develop into any type of blood cell.

25 May 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Study Shows How Excess Dietary Sugar Worsens IBD Symptoms

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

23 May 2023

Revealing the Molecular and Cellular Underpinnings of Summit Disease

Carolyn Elya, a Postdoctoral Researcher in the Department of Organismic and Evolutionary Biology at Harvard, illustrates the molecular and cellular underpinnings of the parasitic fungus Entomophthora muscae’s (E. muscae’s) ability to influence the behavior of fruit flies in new research published in eLife.

22 May 2023

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

The enzyme variations of mitochondrial enoyl-CoA hydratase short-chain 1 (ECHS1) are dysfunctional. In Japan, they are mostly responsible for mitochondrial disease.

19 May 2023

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow.

18 May 2023

Researchers Publish a Detailed Protocol for Making Three Cell Types From iPSCs

Researchers at NIH's National Eye Institute have published a detailed protocol for making three cell types that are key components to form blood vessels and capillaries.

17 May 2023

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response.

17 May 2023

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Researchers at the Josep Carreras Leukaemia Research Institute, led by Dr. Manel Esteller, have discovered a key epigenetic alteration that anticipates the clinical course of liver cancer.

17 May 2023

Researchers Elucidate the Molecular Mechanism of Protein Degradation by Extracellular Chaperones

When exposed to stressful conditions, several proteins tend to misfold and form aggregates inside or outside cells.

12 May 2023

Researchers Reveal the Initiation and Early Stages of Tube Formation in the Sea Star

One of the most basic and crucial embryonic processes to unfold in virtually every living organism is the formation of hollow, tubular structures of various kinds.

10 May 2023

Scientists Engineer the First CRISPR-Based Drug Candidate to Directly Target E. Coli

Many people have experienced infections from E. coli, which are primarily seen as inconvenient and unpleasant.

10 May 2023

Attaching Microbubbles to Macrophages can Create Tracking Images for Tumor Diagnosis

Macrophages, a type of white blood cell, defend the body by engulfing and digesting foreign particles, such as bacteria, viruses, and dead cells.

9 May 2023

T Cells can Fuel Their Ability to Attack Tumors

When you need a bit of motivation, it often has to come from within. New research suggests cancer-fighting immune cells have found a way to do just that.

9 May 2023

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

The immune system has a biological telecommunications system -; small proteins known as interleukins that send signals among the leukocyte white blood cells to control their defense against infections or nascent cancer.

8 May 2023

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

A major challenge in human genetics is understanding which parts of the genome drive specific traits or contribute to disease risk. This challenge is even greater for genetic variants found in the 98% of the genome that does not encode proteins.

5 May 2023

Understanding How Diet may Influence the Gut Microbiota Structure

We know that eating a healthy diet affects body weight, cholesterol levels, and heart health. A new study from the University of Illinois focuses on another component: the role of diet in supporting a healthy gastrointestinal microbiota.

5 May 2023

Blood News and Research

New Insights Into How Genetic Variants Impact Gene Expression

Study Characterizes the Properties of MAIT Cells in Mouse Lung

Fructose is Needed for Enhanced Egg Production in Fruit Flies, Study Reveals

Ex Vivo Expansion of HSCs Using a Novel Culture System

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Study Shows How Excess Dietary Sugar Worsens IBD Symptoms

Revealing the Molecular and Cellular Underpinnings of Summit Disease

A High-Throughput Assay for Identifying and Validating ECHS1 Enzyme Genetic Variants

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Researchers Publish a Detailed Protocol for Making Three Cell Types From iPSCs

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Researchers Elucidate the Molecular Mechanism of Protein Degradation by Extracellular Chaperones

Researchers Reveal the Initiation and Early Stages of Tube Formation in the Sea Star

Scientists Engineer the First CRISPR-Based Drug Candidate to Directly Target E. Coli

Attaching Microbubbles to Macrophages can Create Tracking Images for Tumor Diagnosis

T Cells can Fuel Their Ability to Attack Tumors

Understanding How Interleukin-6 Contributes to Suppress Allergic Asthma and Atopy

STING-seq Discovers Causal Variants and Genetic Mechanisms for Blood Cell Traits

Understanding How Diet may Influence the Gut Microbiota Structure

CITES: Regulating the International Wildlife Trade to Preserve the Viability of Species

How can the adoption of AI technology accelerate drug discovery?

Gaining insights into human disease biology through CRISPR platforms

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