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Researchers employ CRISPR gene-editing technology in human blood to cure HIV

Northwestern Medicine researchers are employing recent developments in CRISPR gene-editing technology to discover novel biological method that could lead to longer-lasting treatments and new therapeutic tactics for the Human Immunodeficiency Virus (HIV).

5 Apr 2022

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Findings from a new Cleveland Clinic-led phase 1 trial show that an experimental "gene silencing" therapy reduced blood levels of lipoprotein(a), a key driver of heart disease risk, by up to 98%.

4 Apr 2022

Research offers new insights for cancer patients to avoid developing metastases

This scientific breakthrough, which was published in the science journal Theranostics, might pave the way for cancer patients to prevent developing metastases.

1 Apr 2022

Researchers discover abnormal gene mutations that lead to cancer development

The reason why the control centers, or nuclei, of certain blood cancer cells, have a peculiar structure is still a mystery.

1 Apr 2022

Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

Scientists from the University of Notre Dame have found a new way for tumor cells to transmit genetic material to other cells in their microenvironment, allowing cancer to spread.

1 Apr 2022

Researchers identify a set of sporadic genetic mutations behind rare brain malformations

A rare type of brain blood vessel malformation known as a cavernous angioma affects more than one million Americans and carries a lifetime risk of stroke and seizures.

31 Mar 2022

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

High blood glucose is responsible for several complications in type 1 and type 2 diabetes. Researchers at Karolinska Institutet in Sweden have identified a new antidiabetic substance that preserves the activity of insulin-producing beta cells and prevents high blood glucose in mice.

31 Mar 2022

Killifish study finds age-dependent loss of antibody diversity

As we age, our immune system works less well. We become more susceptible to infections and vaccinations no longer work as effectively.

29 Mar 2022

Researchers reveal how deleting a protein could prevent heart attacks and strokes

Macrophages travel through our arteries, gobbling fat the way Pac-man gobbled ghosts. But fat-filled macrophages can narrow blood vessels and cause heart disease.

29 Mar 2022

Study reveals genetically driven mucus pathobiology in asthma

A significant amount of genetic risk for asthma is likely mediated through altered gene expression within the airway epithelium.

29 Mar 2022

New approach to assess motility and invasive capacity of cancer cells in a tissue section

There are many proteins involved in the spread of cancer. However, some of them are notably difficult to observe in patient tissue samples.

28 Mar 2022

Study reveals why infected individuals cannot get rid of HIV altogether

Thanks to antiretroviral therapy, HIV infection is no longer the life sentence it once was. But despite the effectiveness of drugs to manage and treat the virus, it can never be fully eliminated from the human body, lingering in some cells deep in different human tissues where it goes unnoticed by the immune system.

28 Mar 2022

Blood News and Research

Researchers employ CRISPR gene-editing technology in human blood to cure HIV

Experimental "gene silencing" therapy reduces a important driver of heart disease risk by up to 98%

Research offers new insights for cancer patients to avoid developing metastases

Researchers discover abnormal gene mutations that lead to cancer development

Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

Researchers identify a set of sporadic genetic mutations behind rare brain malformations

HIF-1alpha inhibitor preserves the activity of insulin-producing beta cells in diabetic mice

Killifish study finds age-dependent loss of antibody diversity

Researchers reveal how deleting a protein could prevent heart attacks and strokes

Study reveals genetically driven mucus pathobiology in asthma

New approach to assess motility and invasive capacity of cancer cells in a tissue section

Study reveals why infected individuals cannot get rid of HIV altogether

Novel protein Atossa regulates cell invasion

Researchers study how trypanosomes change the predatory bug’s intestinal microbiota

Research reveals how a marine bacterium makes a potent anti-cancer molecule

Transcriptomic analysis of Alzheimer's patients reveals early organelle dysfunction in astrocytes

Proteins surrounding organs and tissues switch off natural killer cells’ “killer” function, study finds

Research highlights how genome editing tool CRISPR knocks off genes in cancer cells

ISU researchers receive major funding to go forward on blood stem cells research

Researchers demonstrate how sperms defend their membranes from oxidation

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