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Extrachromosomal DNA with potential to cause cancer drives poor patient outcomes

The multiplication of genes located in extrachromosomal DNA that have the potential to cause cancer drives poor patient outcomes across many cancer types, according to a Nature Genetics study published Aug. 17, 2020 by a team of researchers including Professors Vineet Bafna and Dr.Paul Mischel of the University of California San Diego and Professor Roel Verhaak of Jackson Laboratories.

From UC San Diego 18 Aug 2020

Organ-on-a-chip research explores link between ovarian cancer and blood cells

Recent discoveries made by researchers at Texas A&M University could change the way ovarian cancer is understood and treated.

17 Aug 2020

Study reveals why immunity boost from seasonal flu vaccines is not long lasting

A study from Emory Vaccine Center provides insights into why the boost in immunity from seasonal flu vaccination lasts for months but not years, unlike some childhood vaccinations.

14 Aug 2020

Scientists describe the mechanism of action of therapeutic antibodies

Since the late 1990s, immunotherapy has been the frontline treatment against lymphomas where synthetic antibodies are used to stop the proliferation of cancerous white blood cells.

14 Aug 2020

Antibodies from natural controllers appear to play crucial role in eliminating hepatitis B virus

Infections in humans caused by the hepatitis B virus (HBV) represent a major public health problem. Despite the availability of effective protective vaccines, more than 250 million individuals worldwide are chronically infected according to WHO estimates.

From Institut Pasteur 14 Aug 2020

Detection of cancer using different kind of liquid biopsy

Because cancer is easier to successfully treat when it's caught early, a major goal in cancer research is to develop new ways to find tumors at early stages, before they start to spread. One approach that's being studied are liquid biopsies.

14 Aug 2020

Single-cell analysis uncovers new details concerning mitochondrial diseases

Investigators led by a team at Massachusetts General Hospital (MGH) have made discoveries at the single cell level to uncover new details concerning mitochondrial diseases-- inherited disorders that interfere with energy production in the body and currently have no cure.

14 Aug 2020

A genetic link discovered to predict treatment response for patients with rare, aggressive cancer

A Singapore team led by clinician-scientists and researchers from the National Cancer Centre Singapore (NCCS) discovered a genetic link to better predict treatment response for relapsed/refractory patients with natural- killer T-cell lymphoma (NKTCL), a highly aggressive form of blood cancer.

13 Aug 2020

Exercise induces changes in sweat biomolecule levels, shows study

A new study shows that in addition to blood, endurance exercise induces changes in sweat biomolecule levels. These findings lay the groundwork for the development of future noninvasive exercise monitoring systems that utilize sweat as a biomarker source.

13 Aug 2020

Novel molecule shown to have potential therapeutic effects for arthritis

Arthritis affects almost 2% of the world's population, or some 150 million people, and currently, there is no completely effective treatment for this chronic disease. A new molecule developed in the laboratory has been shown to have potential therapeutic effects.

12 Aug 2020

Simple blood test is useful in screening youth for prediabetes and diabetes

A simple blood test that does not require overnight fasting has been found to be an accurate screening tool for identifying youth at risk for type 2 diabetes and heart disease risk later in life, according to a study from researchers at the Johns Hopkins Bloomberg School of Public Health.

11 Aug 2020

Adapting the equipment and expertise of agtech labs could help combat pandemics

Just as redeploying a fleet of small British fishing boats helped during the Battle of Dunkirk, marshalling the research equipment and expertise of the many agtech labs around the world could help combat pandemics, say the authors of a just-published article in Nature Biotechnology.

11 Aug 2020

Oxytocin can help control and prevent osteoporosis

Oxytocin, produced by the hypothalamus and sometimes known as the "love hormone" for its involvement in pair bonding and orgasm, can be a strong ally in the control and prevention of osteoporosis, according to a study by scientists at São Paulo State University in Brazil.

11 Aug 2020

West Virginia University performs revolutionary Alzheimer's treatment

A hospital nurse for 33 years, Nanette Miller would call her husband Frank at the end of each shift to let him know she was coming home.

10 Aug 2020

Researchers develop new method to diagnose brain tumor without incisions

Brain tumors are typically diagnosed using MRI imaging, as taking a sample for a tissue biopsy is risky and may not be possible due to tumor location or a patient's poor health conditions.

10 Aug 2020

Researchers are developing therapeutic treatments for acute stroke

Every year in the United States, about 800,000 people experience a stroke. Many are left with neurological complications such as paralysis on one side of the body, speech and language problems, vision issues, behavioral changes, and memory loss.

10 Aug 2020

Increased blood lead levels in children are linked to reduced expression of genes

Researchers have revealed a connection between methylation of genes implicated in heme synthesis and carcinogenesis and high blood lead levels in children, signifying a previously unfamiliar mechanism for lead poisoning.

10 Aug 2020

New method targets hidden HIV viral reservoirs during antiretroviral therapy

Scientists at The Wistar Institute may have discovered a new way of identifying and targeting hidden HIV viral reservoirs during treatment with antiretroviral therapy (ART).

10 Aug 2020

New treatment option can improve outcomes in babies with rare cerebrovascular disorder

Endovascular treatment of vein of Galen aneurysmal malformation (VGAM) in babies with severe pulmonary hypertension can improve chances of survival, according to a study released today at the Society of NeuroInterventional Surgery's (SNIS) 17th Annual Meeting.

10 Aug 2020

New technology captures common biomarker of heart-disease

Researchers at the University of Wisconsin-Madison have developed a method combining sticky nanoparticles with high-precision protein measurement to capture and analyze a common marker of heart disease to reveal details that were previously inaccessible.

7 Aug 2020