There are two main types of brain cancer. Primary brain cancer starts in the brain. Metastatic brain cancer starts somewhere else in the body and moves to the brain. Brain tumors can be benign, with no cancer cells, or malignant, with cancer cells that grow quickly. Also called glioma, meningioma.
A group of Northwestern University researchers has created a novel gene editing platform that might influence the future application of a nearly infinite library of CRISPR-based therapeutics.
A discovery regarding how a particular protein is triggered in tumor cells, conducted by researchers at the University of California, Irvine, may lead to more effective therapies for some of the deadliest types of cancer.
Cancer cells can be drawn to certain mechanical “sweet spot” conditions, according to a global team of researchers headed by University of Minnesota Twin Cities engineers.
A new cause of severe childhood brain cancer has been discovered by scientists.
Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.
Researchers from the University of California San Francisco discovered two functional archetypes of metastatic cells spanning seven different types of brain cancers.
For decades, a small group of cutting-edge medical researchers have been studying a biochemical, DNA tagging system, which switches genes on or off. Many have studied it in bacteria and now some have seen signs of it in, plants, flies, and even human brain tumors.
In this interview, we speak to Roy Smythe, CEO of SomaLogic, about their groundbreaking proteomics technology that can simultaneously measure 7,000 proteins.
Unlocking the genetic mysteries behind pediatric brain tumors is at the heart of the mission of the Center for Data Driven Discovery in Biomedicine (D3b) at Children's Hospital of Philadelphia.
A team led by researchers at Weill Cornell Medicine, the New York Genome Center, Harvard Medical School, Massachusetts General Hospital and the Broad Institute of MIT and Harvard has profiled in unprecedented detail thousands of individual cells sampled from patients' brain tumors.
Cells produce exosomes, the nano-sized biological capsules, to protect and courier delicate molecules across the body. The capsules are hard enough to resist enzymatic breakdown and acidic and temperature fluctuations in the bloodstream and gut, which makes them a major candidate for drug delivery.
Researchers have developed a new method that offers novel insights into cancer biology by enabling them to unravel how single cells absorb fatty acids.
A promising treatment for melanoma and other types of cancers is neoadjuvant immune checkpoint blockade (ICB).
A new study coordinated by the University of Trento could have identified the cell of origin of medulloblastoma—a malignant tumor in children that affects the central nervous system. In this study, scientists have used organoids to replicate the tumor tissue, for the first time.
Preclinical research from The University of Texas MD Anderson Cancer Center finds that although glioblastoma stem cells (GSCs) can be targeted by natural killer (NK) cells, they are able to evade immune attack by releasing the TFG-β signaling protein, which blocks NK cell activity.
Medulloblastoma is a rare but devastating childhood brain cancer. This cancer can spread through the spinal fluid and be deposited elsewhere in the brain or spine.
One of the hallmarks of Glioblastoma (GBM), the most aggressive type of brain cancer, is its high invasive capacity, which leads to its expansion into the normal brain tissue.
Researchers at Tel Aviv University have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers.
Australian researchers have identified a protein that could protect the kidneys from 'bystander' damage caused by cancer therapies.
Scientists have designed a new targeted therapy, known as POMHEX, which inhibits vital metabolic pathways in tumor cells containing specific genetic defects.