The lipid-exchanged, anatomically rigid, imaging/immunostaining compatible, tissue hydrogel (CLARITY) method was initially designed in 2013 by Chung and Deisseroth at the Stanford University School of Medicine. Using this process, post-mortem organs can be labeled for proteins and nucleic acids, enabling analysis of intact samples to create detailed 3D images.
Researchers discovered evidence that CTCF governs chromatin accessibility, the mechanism of opening tightly spooled DNA facilitating gene expression.
We are collectively failing to conserve the world's biodiversity and to mobilize natural solutions to help curb global warming. A new study carried out by the Nature Map Consortium, shows that managing a strategically placed 30% of land for conservation could safeguard 70% of all considered terrestrial plant and vertebrate animal species, while simultaneously conserving more than 62% of the world's above and below ground vulnerable carbon, and 68% of all clean water.
A new study achieved the highest-ever resolution imaging of an infectious prion, offering atomic-level data of how these abnormal proteins assemble.
Chemokines are small proteins that adhere to these chemokine receptors and regulate the behavior and movement of white blood cells.
The gold standard in functional brain imaging for over two decades, functional magnetic resonance imaging (fMRI) has transformed the landscape of research and clinical care. Yet, because of its cost and functional limitations, scientists have continued to look for new ways to see into the human brain.
AZoLifeSciences interviews Francesco Branca, director of the Department of Nutrition and Food Safety at the World Health Organization, for World Food Safety Day 2021.
Due to modern agriculture, biodiversity across many species groups is in decline. Over the last three decades, attempts have been made to counteract this with agri-environmental schemes at various levels - from the national federal state to EU-wide programmes.
Researchers have designed a new groundbreaking method that could transform the clarity, precision, and accuracy of super-resolution imaging systems.
NASA-funded research on the 11 largest freshwater lakes in the world coupled field and satellite observations to provide a new understanding of how large bodies of water fix carbon, as well as how a changing climate and lakes interact.
Thanks to modern medicine, humans tend to live much longer than before. Unfortunately, this also opens a wider window to develop chronic diseases with late-onset, such as neurodegenerative diseases.
For decades, scientists have been warning about potential future effects of global climate change, including more frequent wildfires, longer periods of drought, and sharp increases in the number, duration, and intensity of tropical storms.
Tropical islands have an important ally when it comes to battling storms and sea-level rise: seagrass. During hurricane Irma, an extremely powerful Category 5 storm that hit the North Caribbean in 2017, NIOZ scientist Rebecca James witnessed how native seagrass meadows along the coast of Sint Maarten held their ground, reduced coastal erosion and lowered the chances of flooding.
Scientists have made enormous strides in the field of structural biology, looking into the activities of nature at the smallest scale.
Excessive nutrients, such as nitrogen and phosphorus, have devastating effects on coastal marine ecosystems by causing algal blooms that deplete oxygen in the water, killing marine life.
Infancy is a sensitive developmental period that presents opportunities and challenges for caregivers to feed their infants in ways that support healthy growth and development.
Fresh insights into why some harmful substances are so efficient at causing cancer could aid the quest for better treatments.
Silicone molecules extracted from breast implants can trigger the processes in human cells that result in apoptosis.
Cancer is often the result of DNA mutations or problems with how cells divide, which can lead to cells "forgetting" what type of cell they are or how to function properly.
A new study reveals clear evidence highlighting the importance of fish biodiversity to the health of spectacular tropical coral reef ecosystems.
Ion channels that permit potassium and sodium ions to move in and out of cells are essential for the function of the brain and heart, and also for neuronal “firing” in the central nervous system.