Cancer News and Research

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Cancer begins in your cells, which are the building blocks of your body. Normally, your body forms new cells as you need them, replacing old cells that die. Sometimes this process goes wrong. New cells grow even when you don't need them, and old cells don't die when they should. These extra cells can form a mass called a tumor. Tumors can be benign or malignant. Benign tumors aren't cancer while malignant ones are. Cells from malignant tumors can invade nearby tissues. They can also break away and spread to other parts of the body.

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

A next-generation technology that allows the study of protein expression at the single-cell level and the location of the cells within the tumor microenvironment (TME) was feasible and provided information on the benefit of adding the immune checkpoint inhibitor atezolizumab (Tecentriq) to chemotherapy as neoadjuvant treatment for patients with early high-risk and locally advanced triple negative breast cancer (TNBC), according to results presented at the San Antonio Breast Cancer Symposium, held December 7-10, 2021.

8 Dec 2021

World's first metal-organic framework antibody-drug delivery system developed

It sounds like the stuff of science fiction: a man-made crystal that can be attached to antibodies and then supercharge them with potent drugs or imaging agents that can seek out diseased cells with the highest precision, resulting in fewer adverse effects for the patient.

8 Dec 2021

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

In recent years, tumor immunotherapy has emerged as a highly promising and much-touted oncological approach.

8 Dec 2021

Lunaphore highlights novel spatial biology research at SITC 2021

Lunaphore today announced new research from collaborators at the University of Birmingham.

From Lunaphore 7 Dec 2021

Cancer drug effective against Alzheimer’s disease, says research

According to recent research carried out by researchers from the Weill Cornell Medicine, a gene mutation associated with Alzheimer’s disease changes a signaling pathway in specific immune cells of individuals with the disease.

7 Dec 2021

Experts identify first non-coding RNA that controls chromosome loop formation

Recent research carried out by scientists from Massachusetts General Hospital (MGH) reveals that a significant player in the healthy development of female embryos also performs a vital role in controlling the behavior of chromosome loops and gene expression in both sexes.

7 Dec 2021

New nanoparticle adjuvant could lead to more powerful vaccines

A common strategy to make vaccines more powerful is to deliver them along with an adjuvant -; a compound that stimulates the immune system to produce a stronger response.

6 Dec 2021

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

In the late 1980s, scientists developed a revolutionary approach to treating acute myeloid leukemia (AML), a type of blood cancer. Called differentiation therapy, it amounted to a bona fide cure for many patients.

2 Dec 2021

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

2 Dec 2021

Study identifies genes that protect ovarian cancer from antitumor immunity

Immunotherapies are exhibiting better clinical benefit in the treatment of numerous cancers, particularly when used along with chemotherapy.

2 Dec 2021

Experts create new software that determines a person’s past infections

Recent research suggested that grouping of pathogen-recognizing proteins on immune T cells might be vital in pinpointing if an individual had an infection in the past.

2 Dec 2021

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Researchers at Queen’s University boarded a modified Falcon 20 aircraft at Ottawa airport on May 22nd, 2019 as part of a scheduled “vomit comet” flight. In this mode of flight, the plane repeatedly climbs in a steep parabola to 8 km, alternating with a freefall descent.

2 Dec 2021

Study unearths novel mechanism coordinating the assembly of cell components

A group of researchers recently unearthed vital information on how gene expression is orchestrated.

2 Dec 2021

New study shows how neuroblastoma cells deal with rapid division

The cells of a certain tumor type, called neuroblastoma, divide very rapidly. This rapid division can have potentially fatal consequences for them. A new study shows how neuroblastoma cells deal with this dilemma.

1 Dec 2021

Synthetic food additive causes detrimental effects on the gut microbiota

New clinical research indicates that a widely used food additive, carboxymethylcellulose, alters the intestinal environment of healthy persons, perturbing levels of beneficial bacteria and nutrients.

1 Dec 2021

Lung cancer: Cholesterol metabolism of tumor-associated macrophages found to be severely compromised

Significant changes in lipid metabolism are known to occur in cells associated with non-small-cell lung carcinoma – the most common form of lung cancer.

1 Dec 2021

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

CN Bio, a leading developer of single and multi-organ microphysiological systems (MPS), otherwise known as organ-on-a-chip (OOC), today announced the commercial launch of its new PhysioMimix™ OOC Multi-Organ MPS.

From CN Bio Innovations Limited 1 Dec 2021

Researchers show that tumor cells contribute differently to the formation of metastases

A type of cell transformation known as EMT enables cancer cells to break away from the tumor and form metastases elsewhere.

30 Nov 2021

Finding better treatments to eradicate infection caused by H. pylori bacterium

Helicobacter pylori (H. pylori) is one of the most common bacterial infections worldwide, affecting more than 40 % of the population and is one of the causes of digestive symptoms, such as epigastric discomfort, heaviness or bloating of the stomach, or of other more serious diseases, such as the development of gastric and duodenal ulcers, gastric lymphoma or gastric cancer.

30 Nov 2021

Treatment with common allergy medication linked to improved immunotherapy response

New research from The University of Texas MD Anderson Cancer Center found that treatment with antihistamines, a commonly used allergy medication, was associated with improved responses to immune checkpoint inhibitors.

29 Nov 2021

Cancer News and Research

Single-cell spatial analysis may provide information about neoadjuvant therapy for triple-negative breast cancer

World's first metal-organic framework antibody-drug delivery system developed

New strategy to improve the therapeutic efficacy of liver cancer immunotherapy

Lunaphore highlights novel spatial biology research at SITC 2021

Cancer drug effective against Alzheimer’s disease, says research

Experts identify first non-coding RNA that controls chromosome loop formation

New nanoparticle adjuvant could lead to more powerful vaccines

Researchers identify a new approach to triggering differentiation in acute myeloid leukemia

Next-generation sequencing for minimal residual disease proven more sensitive than flow cytometry

Study identifies genes that protect ovarian cancer from antitumor immunity

Experts create new software that determines a person’s past infections

Scientists test the accuracy of enzymes that copy DNA under weightlessness

Study unearths novel mechanism coordinating the assembly of cell components

New study shows how neuroblastoma cells deal with rapid division

Synthetic food additive causes detrimental effects on the gut microbiota

Lung cancer: Cholesterol metabolism of tumor-associated macrophages found to be severely compromised

Introducing the PhysioMimix™ OOC Multi-Organ Microphysiological System

Researchers show that tumor cells contribute differently to the formation of metastases

Finding better treatments to eradicate infection caused by H. pylori bacterium

Treatment with common allergy medication linked to improved immunotherapy response

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