Celiac disease is an inherited autoimmune disorder where gluten has been identified as the environmental trigger of the disease. Gluten is an ingested protein found in wheat, barley and rye. Gluten is broken down into gliadin which can pass through the intestinal epithelial barrier during times of increased intestinal permeability. The ingestion of gluten causes an immune response which triggers an inflammatory reaction in the small intestine. This then causes damage to the villi in the small intestine and can lead to total villous atrophy in celiac disease. This results in varying symptoms such as fatigue, skin rash, anemia, fertility issues, joint pain, weight loss, pale sores inside the mouth, tooth discoloration or loss of enamel, depression, chronic diarrhea or constipation, gas and abdominal pain. The immunology and nutritional abnormalities in celiac disease can potentially result in long- term complications such as osteoporosis, refractory sprue, small intestinal cancer, and lymphoma.
Celiac disease is a growing public health concern, affecting approximately 3 million people in the United States and over 6.5 million people worldwide. The only current management of celiac disease is complete elimination of gluten from the diet, which can be very difficult to implement in practice. Additionally, the response to the gluten-free diet is poor in up to 30% of patients, and dietary nonadherence is the chief cause of persistent or recurrent symptoms.
Cultivated meat, or lab-grown meat, which is made of animal muscle and fat cells grown in a lab, has become a viable option as the world's population grows.
The protein composition of the five types of wheat—einkorn, emmer, spelt, durum, and common wheat—and their varieties differ widely.
A pre-market regulatory status review conducted by the United States Department of Agriculture Animal and Plant Health Inspection Service has concluded that teff modified by genome editing to have a semi-dwarf stature is not subject to biotechnology regulation under USDA's SECURE Rule.
Orange, starchy sweet potatoes are great mashed, cut into fries or just roasted whole. But you likely haven't considered grinding them into a flour and baking them into your next batch of cookies -; or at least, not yet!
Can the SARS-CoV-2 vaccine reactivate previously suppressed antibody responses and pave the way for a unified coronavirus vaccine?
Researchers have completed the sequencing and characterization of the oat genome.
No longer just a dream of vegetarians and vegans, fake meat is becoming more widely available in grocery stores and restaurants. And more options are almost certainly on the way.
Boston College Assistant Professor of Biology Emrah Altindis has received a three-year, $300,000-grant from the G. Harold and Leila Y. Mathers Foundation for research into childhood celiac disease.
A new study of the antibodies produced by people with gluten sensitivity may lead to a better way to detect the condition and treat it.
Several thousand strains of bacteria live in the human gut. Some of these are associated with disease, while others have beneficial effects on human health.
Do chemical pollutants increase the risk of celiac disease? AZoLifeSciences spoke to Abigail Gaylord and Dr. Jeremiah Levine to find out.
An informative applications article from Postnova Analytics demonstrates how its Asymmetrical Field Flow Fractionation technology can be used, with no sample pre-treatment, to separate large gluten proteins and provide accurate molecular weight and molecular size data.
Terms
While we only use edited and approved content for Azthena
answers, it may on occasions provide incorrect responses.
Please confirm any data provided with the related suppliers or
authors. We do not provide medical advice, if you search for
medical information you must always consult a medical
professional before acting on any information provided.
Your questions, but not your email details will be shared with
OpenAI and retained for 30 days in accordance with their
privacy principles.
Please do not ask questions that use sensitive or confidential
information.
Read the full Terms & Conditions.