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New syringe technology for subcutaneous injection of viscous formulations

MIT researchers have developed a simple, low-cost technology to administer powerful drug formulations that are too viscous to be injected using conventional medical syringes.

25 Aug 2020

New approach could slow colon cancer metastasis

When cancer metastasizes and spreads throughout the body, it can severely change the prognosis of the disease. It is estimated that metastasis is responsible for 90 percent of cancer deaths.

25 Aug 2020

Machines match expert human assessment of stored red blood cell quality

Each year, nearly 120 million units* of donated blood flow from donor veins into storage bags at collection centres around the world.

25 Aug 2020

Each person's gut has a unique viral 'fingerprint'

Each person's gut virus composition is as unique as a fingerprint, according to the first study to assemble a comprehensive database of viral populations in the human digestive system.

25 Aug 2020

Lasting nature of IBD linked to long-lived immune cell that causes persistent inflammation

Inflammatory bowel disease (IBD) is a group of intestinal disorders affecting an estimated six to eight million people worldwide.

25 Aug 2020

Microsoft's AI supports the development of Vaxine's COVAX-19 vaccine

Given the global urgency of the COVID-19 pandemic, Microsoft's AI for Health program has stepped in to support the development and potential deployment of Vaxine's COVAX-19™ vaccine with a philanthropic grant.

25 Aug 2020

Rare disorder of fat metabolism can cause chronic hyperreaction of the immune system

A congenital disorder of the fat metabolism can apparently cause chronic hyperreaction of the immune system. This is the conclusion reached by researchers from the University of Bonn in a recent study.

25 Aug 2020

STING protein activates a pathway that kills tumor-fighting immune cells

The immune protein STING has long been noted for helping protect against viruses and tumors by signaling a well-known immune molecule. Now, UT Southwestern scientists have revealed that STING also activates a separate pathway, one that directly kills tumor-fighting immune cells.

25 Aug 2020

Fault in RNA quality control system causes haywire production of toxic proteins

Osaka, Japan - Researchers at Osaka University have identified a fault in the RNA quality control system of cells that leads to the haywire production of toxic proteins in frontotemporal lobar degeneration and amyotrophic lateral sclerosis (FTLD/ALS).

From Osaka University 25 Aug 2020

Study reveals cellular and molecular mechanisms of hypoxic stress and inflammation

Ion channels, transports, and membrane receptors are immediately delivered to defined cellular membranes once they are synthesized in the cytoplasm.

24 Aug 2020

Study shows Annexin molecule promotes resistance to anticancer drugs

Headed by Kumamoto University (Japan), a collaborative study has identified a novel mechanism for anticancer drug resistance in gastric cancer.

24 Aug 2020

Researchers identify a novel molecular mechanism of intestinal stem cells

Stem cells in the intestines maintain an excellent balance between two promising forms—developing into intestinal epithelial cells, or remaining as stem cells.

24 Aug 2020

New study shows promise for developing COVID-19 vaccine

When news about a novel coronavirus switched from a chronicle of its progress in China to headlines about a worldwide COVID-19 pandemic, Gladstone Institutes scientist Nadia Roan, PhD, was in the midst of publishing several papers on T cells and their role in HIV spread and long-lasting infections.

24 Aug 2020

New bioluminescent reporter tracks DNA double stranded break repair in cells

A new bioluminescent reporter that tracks DNA double stranded break (DSB) repair in cells has been developed by researchers from Massachusetts General Hospital (MGH) and the Academia Sinica in Taiwan.

24 Aug 2020

Study provides detailed map of natural killer cell responses to SARS-CoV-2 infection

A new study of 27 patients hospitalized with COVID-19 has provided a detailed map of natural killer (NK) cell responses to SARS-CoV-2 infection, revealing that specific characteristics of NK cell activation associate with different levels of disease severity.

24 Aug 2020

Study provides a SnapShot of FABP proteins linked to obesity

Fatty acid-binding proteins (FABPs), function as a kind of chaperone, synchronizing the transport of various molecules, including fatty acids, between cells.

24 Aug 2020

Study sheds new light on crucial proteins linked to genetic diseases

A new study offers a better understanding of the properties of important proteins found inside the ciliary membrane.

24 Aug 2020

Eliminating tumors with engineered ‘off-the-shelf’ therapeutic T cells

Personalized cancer treatments are no longer just options of the future. In the past few years, researchers have made significant progress in 'teaching' the body's immune T cells to recognize and kill specific cancer cells, and human clinical trials have shown that this approach can successfully eliminate tumors

21 Aug 2020

A metabolic enzyme could be potential target for immunotherapies

The metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system.

21 Aug 2020

'Genetic Code Kit' could transform how biology and biochemistry are taught

An open-source educational biotechnology called the "Genetic Code Kit" has been developed by California Polytechnic State University researchers to allow students to interact with the molecular process inside cells in new ways.

20 Aug 2020