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PFAS chemical helps suppress the neutrophil respiratory burst, study finds

In a new study, researchers found that the PFAS chemical GenX suppresses the neutrophil respiratory burst – the method white blood cells known as neutrophils use to kill invading pathogens.

16 Feb 2023

Researchers establish and characterize a stable iPSC line for modeling human disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

New open-access database provides a map of the proteome signature

The recently released cancer protein profile database, which was created using AI and machine learning, has helped with cancer prediction medicine. The new open-access Disease Blood Atlas, unveiled by KTH Royal Institute of Technology Professor Mathias Uhlén, gives the first-ever map of the proteome signature in cancer patients’ blood.

11 Jan 2023

Fastest-evolved regions of the human genome diverged rapidly after split from chimpanzee ancestor

A team of Duke researchers has identified a group of human DNA sequences driving changes in brain development, digestion and immunity that seem to have evolved rapidly after our family line split from that of the chimpanzees, but before we split with the Neanderthals.

24 Nov 2022

Revealing the functional significance of DDX41 in great detail

The DDX41 gene encodes the nuclear enzyme DEAD-box-type RNA helicase. Hematopoietic malignancies are caused by DDX41 mutations. However, the mechanism behind the development of this malignancy remains unknown.

21 Nov 2022

Rapid fluctuations in electrical activity within breast cancer cells identified

Recent research has discovered that the membranes of breast cancer cells have varying voltages, revealing information regarding their growth and spread.

15 Nov 2022

Novel method tags proteins from specific cancer cells

Biomarkers are extremely useful tools that enable doctors to research biology and disease by, for instance, diagnosing a disease from a blood or tissue sample, predicting whether a treatment will be beneficial in a person, or determining how much of a drug is entering diseased cells.

28 Oct 2022

Innovative method opens myriad new avenues for understanding the biology behind COVID-19

A highly innovative method using the latest technology has generated a comprehensive list of SARS-CoV-2 viral and human proteins that interact with each other, with one such interaction showing the virus directly influencing proteins that regulate the human immune system.

18 Oct 2022

Characterizing the transcription profile of microglia in a mouse model

Researchers from Tohoku University have now shown that the consolidation and extinction of contextual fear conditioning alter the microglial genes connected to the synapse—structures that permit neurons to communicate with one another.

13 Sep 2022

Researchers create novel human cell line to explore blinding eye disorders

Researchers at the LSU Health New Orleans Neuroscience Center of Excellence have created a novel, experimental human cell line from retinal pigment epithelial cells, under the supervision of Boyd Professor Nicolas Bazan, MD, PhD.

14 Jul 2022

Scientists link the function of specific domain of proteins to a cancer trigger in humans

Researchers at the Department of Energy's Oak Ridge National Laboratory have definitively linked the function of a specific domain of proteins important in plant-microbe biology to a cancer trigger in humans, knowledge that had eluded scientists for decades.

6 Jul 2022

Researchers discover effective therapy for pediatric T-acute leukemia

The most frequent type of malignancy in kids is acute lymphoblastic leukemia (ALL).

27 Jun 2022

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

Hypomethylating agents (HMA) are currently used as a first-line treatment for patients with myelodysplastic syndrome (MDS) - a group of disorders where there is insufficient production of healthy mature blood cells in the bone marrow - and increasingly in other diseases, but their mechanism of action remains unclear.

From National University of Singapore (NUS) 27 May 2022

Cell Line News and Research

PFAS chemical helps suppress the neutrophil respiratory burst, study finds

Researchers establish and characterize a stable iPSC line for modeling human disease

New open-access database provides a map of the proteome signature

Fastest-evolved regions of the human genome diverged rapidly after split from chimpanzee ancestor

Revealing the functional significance of DDX41 in great detail

Rapid fluctuations in electrical activity within breast cancer cells identified

Novel method tags proteins from specific cancer cells

Innovative method opens myriad new avenues for understanding the biology behind COVID-19

Characterizing the transcription profile of microglia in a mouse model

Researchers create novel human cell line to explore blinding eye disorders

Scientists link the function of specific domain of proteins to a cancer trigger in humans

Researchers discover effective therapy for pediatric T-acute leukemia

Drugs used for myelodysplastic syndrome could potentially activate a sleeping oncogene

National DNA Day 2022: an interview with Professor Matthew Cobb

High performance microplates for enhanced cell growth and survival

Scientists produce the first complete, gapless sequence of a human genome

Researchers discover a novel pathway for DNA transfer in the tumor microenvironment

Orbit Discovery and WuXi AppTec sign agreement to access peptide discovery and optimisation technologies

Simple lab model helps investigate the properties of muscle cells from sIBM patients

Researchers identify a sound-sensitive mammalian protein

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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