Cell Metabolism News and Research

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Using State-of-the Art Imaging to Understand Lipid Dysfunction in Alzheimer's

Alzheimer's disease causes significant problems with memory, thinking and behavior and is the most common form of dementia, affecting more than 50 million people around the world each year.

24 Apr 2024

How Glucocorticoids Quell Inflammation

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions.

13 Apr 2024

New Theory Links Gene Length to Cellular Decline

A gene’s length may have more to do with aging than particular “aging genes.” Reduced expression of long genes may be the cause of many aging-related changes, according to researchers writing an opinion piece that was published in the journal Trends in Genetics on March 21st, 2023.

25 Mar 2024

Unraveling the Role of Gene Length in Aging

Aging may be less about specific "aging genes" and more about how long a gene is. Many of the changes associated with aging could be occurring due to decreased expression of long genes, say researchers in an opinion piece publishing March 21 in the journal Trends in Genetics.

22 Mar 2024

Targeting T Cell Metabolism to Boost Cancer Therapies

Recent findings from the lab of Jessica Thaxton, PhD, MsCR, in the UNC School of Medicine's Department of Cell Biology and Physiology, as well as associates in the Lineberger Comprehensive Cancer Center's Immunotherapy Group, have provided new insights into T-cell metabolism that may improve immunotherapies that depend on T cells to combat cancer.

18 Mar 2024

Gut Microbial Metabolite Linked to Increased Thrombosis Risk in COVID-19 Patients

A gut microbial metabolite called 2-methylbutyrylcarnitine (2MBC) plays a role in exacerbating thrombosis -- the formation of blood clots – researchers report February 23rd in the journal Cell Metabolism.

26 Feb 2024

The Evolutionary Timeline of Diminished Boric Acid and Urea Transportation in Aquaporin 10

Aquaporin (Aqp) 10 water channels in humans allow the free passage of water, glycerol, urea, and boric acid across cells.

27 Dec 2023

Unlocking the Secrets of Nerve Regeneration

Injuries to the peripheral nerves of the body can lead to pain and movement disorders. A recent investigation by Leipzig University delved into enhancing the regeneration of damaged nerves.

29 Nov 2023

Macrophages Play Central Role in Intestinal Cell Renewal

A research team comprising members from MedUni Vienna and the FWF-sponsored Special Research Area SFB F83 Immunometabolism has made a groundbreaking discovery, highlighting the central role of macrophages in the regeneration of intestinal cells.

11 Oct 2023

New Synthetic Catalyst Breaks Down Cellulose: Study

Yan Zhao gestured toward the trees outside his campus window on a rainy afternoon.

22 Aug 2023

New Insights Into Lactate Transporters and Their Therapeutic Potential

Researchers from the Giulio Superti-Furga Lab at CeMM, the Austrian Academy of Sciences’ Research Center for Molecular Medicine, have developed a new technique for identifying specific inhibitors of a lactate transporter linked to cancer and other diseases.

31 Jul 2023

Dad’s Genes “Remote Control” Mom’s Metabolism to Benefit Fetus

The unborn baby “remote controls” its mother’s metabolism, resulting in a nutritional tug-of-war between the two. The mother’s body requires the baby to survive, but she also needs enough glucose and fats in her system to be able to deliver the baby, breastfeed, and reproduce again.

12 Jul 2023

Research may Offer a New Way to Break Through Cancer's Hypoxia-Induced Defenses

For most of our tissues and cells, a lack of oxygen, or hypoxia, is bad news. Cancer cells, on the other hand, can thrive in these hypoxic conditions, which render tumors less susceptible to anti-cancer treatments, including radiation.

11 Jul 2023

Study Characterizes the Properties of MAIT Cells in Mouse Lung

A population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike.

26 May 2023

Targeting Cellular Respiration for the Treatment of Glioblastoma

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Targeting cellular respiration as a therapeutic strategy in glioblastoma."

22 May 2023

Study Uncovers Cancer-Like Changes in Mitochondrial Disease of Newborns

A study found that a mitochondrial disease of newborns shows cancer-like changes in proliferating cells, causing tissues to age prematurely.

4 May 2023

Glycine-Based Tripeptide Treats Severe Form of Fatty Liver Disease in Non-Human Primates

A recently developed amino acid compound successfully treats nonalcoholic fatty liver disease in non-human primates -; bringing scientists one step closer to the first human treatment for the condition that is rapidly increasing around the world, a study suggests.

11 Apr 2023

Two subtypes of cells that produce insulin discovered

A team of scientists from the Van Andel Institute and the Max Planck Institute for Immunobiology and Epigenetics uncovered two unique subtypes of insulin-producing beta cells, or ß cells, each having important traits that could potentially be used to better understand and treat Type 1 and Type 2 diabetes.

30 Mar 2023

Foods with a high fat and sugar content change our brain, shows study

Chocolate bars, crisps and fries - why can't we just ignore them in the supermarket? Researchers at the Max Planck Institute for Metabolism Research in Cologne, in collaboration with Yale University, have now shown that foods with a high fat and sugar content change our brain: If we regularly eat even small amounts of them, the brain learns to consume precisely these foods in the future.

23 Mar 2023

Using PET and electron microscopy to generate 3D maps of mitochondrial networks in lung tumors

Scientists have long known that mitochondria, the "powerhouses" of cells, play a crucial role in the metabolism and energy production of cancer cells.

16 Mar 2023