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SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Researchers from the Critical Analytics for Manufacturing Personalized-Medicine (CAMP) Interdisciplinary Research Group (IRG) of Singapore-MIT Alliance for Research and Technology (SMART), MIT’s research enterprise in Singapore, in collaboration with the Agency for Science, Technology and Research (A*STAR) Bioprocessing Technology Institute (BTI) and National University Health System (NUHS), have developed a groundbreaking technology.

22 Nov 2023

Human Pluripotent Stem Cells Converted into Purified Pituitary Tissue

Human pluripotent stem cells were effectively transformed into purified pituitary cells, which aggregated into hormone-secreting organoids.

9 Jun 2023

Prime Target for Male Contraceptive Development Identified

As far as a highly effective, reversible, and non-hormonal male contraceptive for humans and animals is concerned, the discovery of a gene in multiple mammalian species could set the stage.

18 Apr 2023

Thrive Bioscience launches new CellAssist family product capabilities to advance live cell imaging

Thrive Bioscience Inc., an innovative provider of automated live cell imaging instruments and software, debuts a new integrated suite of unique and exciting capabilities that significantly advance the field of live cell imaging.

24 Feb 2023

Extended generation of blood cells in wild-type animals from pluripotent stem cells

Cells present in the blood like red blood cells, immune cells, and other crucial cell types are renewed continually from stem cells, the alleged hematopoietic stem and progenitor cells (HSPCs).

17 Feb 2023

New genetic condition that raises vulnerability to opportunistic infections

An international consortium co-led by Vanderbilt University Medical Center immunogeneticist Rubén Martínez-Barricarte, PhD, has discovered a new genetic disorder that causes immunodeficiency and profound susceptibility to opportunistic infections including life-threatening fungal pneumonia.

24 Jan 2023

Grasping how a biological pathway causes stem cells to regenerate or die

According to a recent study conducted by Cedars-Sinai and the University of California, San Francisco (UCSF), altering a cellular process can cause stem cells, which are the cells that give rise to all other types of body cells, to either die or regenerate.

18 Jan 2023

Novel blood biomarker predicts a favorable response to CART cell therapy

A MedUni Vienna research group identified a particularly potent biomarker for clinical response to CAR-T cell therapy, establishing the conditions for the most effective use of this innovative therapy for lymphoma treatment.

11 Jan 2023

Figuring out how immune cells prevent cognitive decline

Could Alzheimer’s disease and other types of cognitive decline be caused by the underproduction of immune cells that are poorly understood? It might, according to a Rutgers study published in Nature Immunology, and increasing these cells could undo the harm.

From Rutgers University 1 Dec 2022

Bacterial warfare in the gut can have collateral beneficial effects

Nearly ten years ago, a graduate student at UO Jennifer Hampton Hill stumbled upon something fortunate: a peptide produced by gut bacteria that prompted the division of cells that make insulin.

17 Oct 2022

Yeast platform for the production of plant-derived anti-cancer drug

The supply of a plant-derived anti-cancer drug can finally meet global demand after a team of scientists from Denmark and the U.S. engineered yeast to produce the precursor molecules, which could previously only be obtained in trace concentrations in the native plant.

1 Sep 2022

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

The potential of CAR T-cell therapy for the treatment of solid tumors was unlocked in a preclinical trial by researchers at St. Jude Children’s Research Hospital who discovered a molecular mechanism. The findings were released in the journal Nature.

27 Jun 2022

Researchers find increased red blood cell destruction in astronauts

A change in the volume of red blood cells has been documented in astronauts since the earliest space missions.

7 Mar 2022

Earlier onset of growing season in cold humid areas may benefit tree growth

A research group led by Prof. Liang Eryuan from the Institute of Tibetan Plateau Research of the Chinese Academy of Sciences has found that trees may benefit from an earlier start of the growing season in cold humid areas, but not in dry areas.

1 Mar 2022

Hematopoietic stem cells play key focus of stem-cell-based medical research

According to a recent study, a protein that controls how DNA is wrapped within chromosomes plays a key role in the proper functioning of blood stem cells.

2 Feb 2022

Research highlights opportunities to expand the manufacture of stem cells in space

The secret to producing large batches of stem cells more efficiently may lie in the near-zero gravity conditions of space. Scientists at Cedars-Sinai have found that microgravity has the potential to contribute to life-saving advances on Earth by facilitating the rapid mass production of stem cells.

3 Jan 2022

Cell Production News and Research

SMART Researchers Pioneer Novel Microfluidic Method to Optimize Bone Marrow Stem Cell Extraction for Advanced Cell Therapies

Human Pluripotent Stem Cells Converted into Purified Pituitary Tissue

Prime Target for Male Contraceptive Development Identified

Thrive Bioscience launches new CellAssist family product capabilities to advance live cell imaging

Extended generation of blood cells in wild-type animals from pluripotent stem cells

New genetic condition that raises vulnerability to opportunistic infections

Grasping how a biological pathway causes stem cells to regenerate or die

Novel blood biomarker predicts a favorable response to CART cell therapy

Figuring out how immune cells prevent cognitive decline

Bacterial warfare in the gut can have collateral beneficial effects

Yeast platform for the production of plant-derived anti-cancer drug

Scientists discover proteins that may improve CAR-T cell therapy for solid tumor model

Researchers find increased red blood cell destruction in astronauts

Earlier onset of growing season in cold humid areas may benefit tree growth

Hematopoietic stem cells play key focus of stem-cell-based medical research

Research highlights opportunities to expand the manufacture of stem cells in space

Researchers uncover a new signaling pathway essential for T cell viability

Multiple changes in brain cells during embryonic development may contribute to schizophrenia

Study reveals mechanism by which infections strengthen the immune system

Treatment with common allergy medication linked to improved immunotherapy response

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The Last Piece of Our Genome: Sequencing the Y Chromosome

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