Cellular Biology News and Research

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"Visual Biochemistry" Approach to Understand How the BRCA2 Protein Binds and Interacts with DNA

Using a self-built inverted microscope complete with laser optical tweezers to capture DNA, Yale Cancer Center and University of California Davis researchers for the first time created a visualization of the full-length human BRCA2 protein at the single molecule level.

3 Apr 2023

Researchers find methods to awaken and revive neural stem cells

Some areas of the adult brain contain quiescent, or dormant, neural stem cells that can potentially be reactivated to form new neurons. However, the transition from quiescence to proliferation is still poorly understood. A team led by scientists from the Universities of Geneva (UNIGE) and Lausanne (UNIL) has discovered the importance of cell metabolism in this process and identified how to wake up these neural stem cells and reactivate them. Biologists succeeded in increasing the number of new neurons in the brain of adult and even elderly mice. These results, promising for the treatment of neurodegenerative diseases, are to be discovered in the journal Science Advances.

2 Mar 2023

Ten years and 1,000 studies later, epigeneticists discover problems in their arsenal

Twenty years ago, following the initial sequencing of the human genome, geneticists started carrying out extensive genome-wide association studies to find genomic regions connected to human disease.

16 Jan 2023

Identifying the structure of the SEA complex

The mTOR protein is important for cell growth, proliferation, and survival. Its activity fluctuates according to nutrient availability and growth factors like hormones.

1 Nov 2022

Coral genome reveals cysteine biosynthesis pathways

Model animals, such as mice and fruit flies, have provided scientists with powerful insights into how cellular biology works. However, model animals are really just a guide, and it can be risky to generalize findings across animals from studying a selection of model organisms.

26 Sep 2022

Gut microbiota plays a major role in alcohol consumption, a new study reveals

According to the findings of a research team conducted by the Complutense University of Madrid (UCM), the various gut microbiota compositions contribute to the explanation of the various patterns of alcohol consumption amongst individuals.

28 Jul 2022

Scientists identify a new soil amoeba species in Chernevaya taiga

In the Chernevaya taiga, in the south of Western Siberia, scientists from St Petersburg University identified a new soil amoeba species Leptomyxa silvatica n. sp. with colleagues from Tomsk and Novosibirsk.

25 Apr 2022

Study highlights quality control pipeline method to analyze single-cell variation

When it comes to assessing the effects of endocrine-disrupting chemicals (EDCs) or toxins on cancers and other diseases, which target a variety of mechanisms, including the estrogen receptor (ER), one size does not always fit all.

20 Apr 2022

Researchers discover new type of cell that may play a key role in human lung diseases

A new type of cell that resides deep within human lungs and may play a key role in human lung diseases has been discovered by researchers at the Perelman School of Medicine at the University of Pennsylvania.

4 Apr 2022

Tuberculosis causes early epigenetic aging in cells, study finds

In the current study, scientists at Baylor College of Medicine identified that the cells of humans and animals that recovered from tuberculosis had prematurely aged up to 12 to 14 years.

25 Mar 2022

Protein appears key to the function and survival of brain cells most impacted by glaucoma

A ubiquitous protein called sigma 1 receptor, which is known to protect cells from stress, appears key to the function and survival of the neurons most impacted by glaucoma, scientists report.

2 Mar 2022

New computer tool identifies over 100,000 novel viruses

Viruses are the major group of biological agents widely recognized.

4 Feb 2022

Scientists visualize protein machinery of respiration with unparalleled precision

Oxygen and sugar are the basis of life for animals, plants, fungi and many bacteria. The metabolic process called respiration makes it possible to convert food into energy for the cells.

1 Feb 2022

Peptide-enhanced, biological cancer drug may help treat breast cancer metastasis to bone

A moderate amount of a peptide-enhanced, biological cancer drug goes a long way in treating breast cancers that metastasize to the bone.

25 Jan 2022

Study finds gene family that regulates tissue-specific DNA methylation patterns

According to researchers at Salk, the CLASSY gene family controls which portions of the genome are turned off in a tissue-specific manner.

13 Jan 2022

Targeting MAPK4 in triple-negative breast cancer may lead to improved treatments

Scientific evidence supporting the involvement of the enzyme MAPK4 in cancer growth and resistance to certain therapies has been growing quickly.

12 Jan 2022

Study unearths novel mechanism coordinating the assembly of cell components

A group of researchers recently unearthed vital information on how gene expression is orchestrated.

2 Dec 2021

Genetically modified plants can produce and release insect sex pheromones to deal with pests

A team of researchers from the Universitat Politècnica de València (UPV) and the Spanish National Research Council (Consejo Superior de Investigaciones Científicas, CSIC) has developed genetically modified plants that are capable of producing and releasing insect sex pheromones to deal with pests that affect herbaceous and similar plants, thus reducing the need for using pesticides.

18 Nov 2021

Advanced tools for Glycobiology research

Drawing upon over 30-years’ experience of serving the glycobiology research community - AMSBIO has established a comprehensive portfolio of high-quality reagents including unique ranges of antibodies, lectins, enzymes, assay kits and standards, backed by in-depth technical support.

From AMS Biotechnology 16 Nov 2021

Naturally occurring protein that blocks inflammatory response linked to better stroke recovery in mice

A naturally occurring protein that blocks an inflammatory immune response was associated with better stroke recovery in a study conducted in mice, according to preliminary research to be presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2021.

23 Sep 2021