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New gene may affect the upper motor neuron cells in the nervous system, study reveals

A recent genetic finding supports the theory that abnormal lipid (fat) transport pathways inside brain cells cause motor neuron degenerative disorders.

From University of Exeter 20 Jun 2022

Plastic pollution in the ocean may serve as a source for novel antibiotics

Plastic pollution in the ocean may serve as a source for novel antibiotics, according to a new student-led study conducted in collaboration with the Scripps Institution of Oceanography.

20 Jun 2022

Researchers understand the mystery behind DNA rings

Professor Dr Anton Henssen of Charité – Universitätsmedizin Berlin and the Helmholtz Association’s Max Delbrück Center (MDC) for Molecular Medicine, along with a group of researchers from the United States and the United Kingdom, have received a grant for a Cancer Grand Challenge.

17 Jun 2022

Stanford scientists develop fingertip-sized millirobots to improve targeted drug delivery

If you've ever swallowed the same round tablet in hopes of curing everything from stomach cramps to headaches, you already know that medicines aren't always designed to treat precise pain points.

17 Jun 2022

Lager beer consumption may increase men’s gut microbiome’s diversity

Like wine, beer can have health benefits when consumed in moderation. Non-alcoholic beers have become wildly popular recently, but are these drinks also healthful?

16 Jun 2022

Differentiation protocol can develop safe and efficient pluripotent stem cell-based therapies for AMD

As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems.

16 Jun 2022

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

Funding will enable the development of Spirea’s pipeline of antibody drug conjugate therapeutics for the treatment of solid tumours.

From Spirea 14 Jun 2022

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

Researchers at The University of Texas MD Anderson Cancer Center have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which contain both cancer and non-cancer cells.

14 Jun 2022

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

To drive anabolic processes, epithelial ovarian cancer (EOC) is heavily reliant on the tricarboxylic acid (TCA) cycle and oxidative phosphorylation.

13 Jun 2022

Researchers discover a new interferon-gamma receptor signaling pathway

The interferon-gamma receptor (IFNgR) signaling pathway has been identified to be crucial for the vulnerability of glioblastoma tumors to death by CAR T-cell immunotherapy, according to researchers at Massachusetts General Hospital (MGH).

10 Jun 2022

Dietary modifications can lower symptoms of allergic reactions, a new study reveals

Micronutrient deficits can increase inflammation and make the immune system more susceptible to allergens. Iron deficiency indicates danger to immune cells and causes an excessive immunological response.

8 Jun 2022

Novel insights into how some bacteria evade antibiotics

Scientists have revealed how antibiotics can regress certain fast-growing bacteria. The research was published in the journal eLife on June 8th, 2022.

8 Jun 2022

Axol Bioscience introduces CiPA-validated human stem cell-derived ventricular cardiomyocytes to help improve drug discovery

Axol Bioscience Ltd. (Axol), an established provider of iPSC-derived cells, media, and characterization services for life science discovery, today announced that its human induced pluripotent stem cell (iPSC)-derived ventricular cardiomyocytes have undergone comprehensive in vitro pro-arrhythmia assay (CiPA) validation.

From Axol Bioscience Ltd 8 Jun 2022

Study discovers new antibiotics effective against drug-resistant tuberculosis

Every year, 1.5 million people die from infections caused by Mycobacterium tuberculosis. Antibiotics are available to treat tuberculosis, but the bacteria has evolved multi-drug resistant (MDR), extensively drug-resistant (XDR), and fully drug-resistant (TDR) strains in recent years.

1 Jun 2022

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Proteins are made in cells in the same way as they are made in factories. However, making too much at the wrong moment may lead to illnesses like cancer, so they use RNA interference (RNAi) to regulate production.

1 Jun 2022

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Highly structured chromatin encodes the program of life with only one set of genes in the core of every cell. Since various genes are stimulated at different periods of life while staying silent elsewhere, this is feasible. Some genes from a former life stage are hidden deep within the nuclear perimeter, while others manage to break out.

1 Jun 2022

Researchers analyze the involvement of immune cells in lung cancer survival

Lung cancer affects approximately 48,500 persons in the United Kingdom every year. New treatments are urgently needed because only around 20% of patients live 5 years after diagnosis, and it is the leading cause of cancer death.

1 Jun 2022

Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

The University of Texas MD Anderson Cancer Center scientists have created an ultrasound-guided cancer immunotherapy approach that promotes systemic antitumor immunity and increases immune checkpoint blockade therapeutic potential. Nature Nanotechnology published the results of the pioneering study.

1 Jun 2022

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

An international collaboration of scientists has discovered a new technique to kill cancers that are difficult to treat, according to an article published in Nature.

30 May 2022

Researchers determine the novel medical target of angiogenesis for ccRCC patients

Research reported that the DMDRMR/miR-378a-5p/ DAB2IP axis enhances angiogenesis and sunitinib resistance, suggesting that it could be used for patients with ccRCC.

30 May 2022

Clinical News and Research

New gene may affect the upper motor neuron cells in the nervous system, study reveals

Plastic pollution in the ocean may serve as a source for novel antibiotics

Researchers understand the mystery behind DNA rings

Stanford scientists develop fingertip-sized millirobots to improve targeted drug delivery

Lager beer consumption may increase men’s gut microbiome’s diversity

Differentiation protocol can develop safe and efficient pluripotent stem cell-based therapies for AMD

Spirea raises £2.4M ($3M) to develop antibody drug conjugates in cancer

Computational approach could enable large-scale analyses of tumor-specific total mRNA levels from patient samples

ZDHHC18-mediated MDH2 palmitoylation upholds mitochondrial respiration and boosts ovarian cancer malignancy

Researchers discover a new interferon-gamma receptor signaling pathway

Dietary modifications can lower symptoms of allergic reactions, a new study reveals

Novel insights into how some bacteria evade antibiotics

Axol Bioscience introduces CiPA-validated human stem cell-derived ventricular cardiomyocytes to help improve drug discovery

Study discovers new antibiotics effective against drug-resistant tuberculosis

Study reveals how RNAi workhorse protein optimizes to keep protein synthesis on track

Researchers conduct a comprehensive survey of the aging epigenome across the chromatin hierarchy

Researchers analyze the involvement of immune cells in lung cancer survival

Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

Scientists discover a new left-handed Z-DNA technique to kill hard-to-treat tumors

Researchers determine the novel medical target of angiogenesis for ccRCC patients

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