Craniofacial News and Research

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Cellular Insights Into Facial Morphogenesis

Mother Nature is an artist, but her craft of creating animal faces requires more than a paintbrush and palette. Such highly complex shapes originate from their respective transient neural crest cells.

12 Apr 2024

Insights Into the Genetic Landscape of Human Head Shape

A collaborative research team from the University of Pittsburgh and KU Leuven has identified a set of genes that influence the shape of the human head.

20 Nov 2023

Novel Genetic Disorder Associated With Neurodevelopmental Differences Discovered

Researchers from Children's Hospital of Philadelphia and Princeton University have discovered a novel genetic disorder associated with neurodevelopmental differences.

27 Apr 2023

Researchers Identify Genes Responsible for Craniofacial Dysmorphology in Down Syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

27 Apr 2023

Newly Discovered Mechanism may Have Profound Implications for Colorectal Cancer Prevention

Researchers at the Forsyth Institute have discovered an important mechanism that may have profound implications for how we prevent colorectal cancer. Oddly enough, their discovery began in the mouth.

5 Apr 2023

Innovative new approach to constructing a nose in young patients with arhinia

Congenital arhinia (meaning patients born without a nose) is a rare condition associated with high mortality if not identified.

24 Mar 2023

Study finds similar levels of DNA damage in vapers and smokers

E-cigarettes-; used regularly by more than 10% of U.S. teens and more than 3% of adults-; were once pitched as a healthy alternative to tobacco cigarettes.

14 Feb 2023

Key genes driving cleft lip and palate identified

A research group headed by the University of Iowa recognized three genes that, when deleted, produce cleft lip or palate, a facial abnormality that affects around one in every 1,600 babies in the United States, according to the US Centers for Disease Control and Prevention.

13 Jan 2023

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Researchers at Johns Hopkins Medicine say they have created a laboratory-grown three-dimensional "organoid" model that is derived from human tissue and designed to advance understanding about how early stages of cancer develop at the gastroesophageal junction (GEJ) — the point where the digestive system's food tube meets the stomach.

2 Dec 2022

Gaining better insights into the origins of jaws by DNA sequence

At Uppsala University, a DNA sequence found in jawed vertebrates has been discovered and characterized by scientists. This includes sharks and humans, but it is absent in jawless vertebrates, like lampreys.

28 Nov 2022

Scientists discover a special cell in salivary glands that is likely crucial for oral health

Scientists at Scripps Research and the National Institute of Dental and Craniofacial Research have discovered a special type of cell that resides in salivary glands and is likely crucial for oral health.

13 Apr 2022

Researchers determine major protein complexes that cause ribosome production

Scientists at UT Southwestern have discovered a four-protein complex that seems to play a significant function in the formation of ribosomes, which serve as protein factories for cells, as well as a surprise role in neurodevelopmental diseases.

1 Apr 2022

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

Blocking function of a blood-clotting protein prevented bone loss from periodontal (gum) disease in mice, according to research led by scientists at the National Institute of Dental and Craniofacial Research (NIDCR), part of the National Institutes of Health.

24 Dec 2021

Craniofacial News and Research

Cellular Insights Into Facial Morphogenesis

Insights Into the Genetic Landscape of Human Head Shape

Novel Genetic Disorder Associated With Neurodevelopmental Differences Discovered

Researchers Identify Genes Responsible for Craniofacial Dysmorphology in Down Syndrome

Newly Discovered Mechanism may Have Profound Implications for Colorectal Cancer Prevention

Innovative new approach to constructing a nose in young patients with arhinia

Study finds similar levels of DNA damage in vapers and smokers

Key genes driving cleft lip and palate identified

New 3D organoid model reveals a possible biological target for treating GEJ cancers

Gaining better insights into the origins of jaws by DNA sequence

Scientists discover a special cell in salivary glands that is likely crucial for oral health

Researchers determine major protein complexes that cause ribosome production

Blocking function of blood-clotting protein prevents bone loss from gum disease in mice

Study identifies how embryonic cells detect stiffness in their environment

New 3D map provides precise locations of blood vessels and stem cells in a a mouse skull

Gene therapy may be a safe and effective single-dose treatment for hypophosphatasia

New wiki promotes development of innovative saliva-based diagnostic tests and customized treatment

Salivary gland cells could play role in SARS-CoV-2 virus transmission

Scientists use stem cells to reverse memory and learning deficits in mice with craniosynostosis

Researchers identify new gene involved in neurodevelopmental disorders

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