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Novel Assay Platform for 3D Microfluidic Cancer Research

AMSBIO have supplied custom Chimeric antigen receptor (CAR)-T products to the University of Strathclyde (UoS) in Glasgow, UK, and ScreenIn3D Ltd, allowing them to perform novel immune-oncology assays in 3D microfluidic cancer models.

From AMS Biotechnology 1 Oct 2021

Mast cell precursor cells get activated when exposed to allergic stimulation, shows study

Mast cell precursor cells do not just cause an increase in mature mast cells during inflammation, they also play an active role in diseases like asthma. This finding is in a new study by immunology researchers published in the Journal of Allergy and Clinical Immunology.

1 Oct 2021

Poor systemic immune responses and elevated MAIT cell activation linked to fatal COVID-19 infections

The mortality rate of COVID-19 patients requiring mechanical ventilation is 30-40%, however, the immunological factors associated with death in critically ill COVID-19 patients are poorly understood.

17 Sep 2021

Scientists explore whether consuming cocoa can help us age better

Whether consuming cocoa, known to be packed with powerful antioxidants that protect our cells from damage, helps us age better, is a question scientists want to definitively answer.

14 Sep 2021

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

The emergence of the COVID-19 pandemic in the United States in early 2020 left researchers struggling to identify lab models of SARS-CoV-2 infection.

From UC San Diego 2 Sep 2021

Study uncovers key factors immune cells need to survive in the battle against cancer

A study headed by scientists at Massachusetts General Hospital unravels certain crucial factors required for the survival of immune cells in the fight against cancer.

12 Aug 2021

Cytokines play a role in regulation of beige fat

An immune signal promotes the production of energy-burning "beige fat," according to a new study publishing August 5th in the open-access journal PLOS Biology by Zhonghan Yang of Sun Yat-Sen University, Guangzhou, China, and colleagues.

6 Aug 2021

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Researchers propose that similar to pouring water atop a wellhead prior to pumping, the airway cells of patients suffering from chronic lung diseases are “primed” for infection by the COVID-19 virus.

16 Jul 2021

Study on memory T cells of COVID-19 convalescent patients could power effective vaccine strategies

Researchers have discovered that a majority of the COVID-19 convalescent patients develop and maintain T cell memory for more than 10 months.

7 Jul 2021

New consortium of bacteria can be used to treat aggressive colitis in humanized mouse models

A new study reported in Nature Communications shows that a consortium of bacteria, developed to complement lacking or poorly represented functions in the imbalanced microbiome of inflammatory bowel disease (IBD) patients, inhibited and treated chronic immune-mediated colitis in humanized mouse models.

31 May 2021

Novel drug is highly effective in preventing severe COVID-19 in mice

The drug diABZI -- which activates the body's innate immune response -- was highly effective in preventing severe COVID-19 in mice that were infected with SARS-CoV-2,

31 May 2021

Study reveals urine protein biomarkers of bladder cancer

Oncotarget published "Urine protein biomarkers of bladder cancer arising from 16-plex antibody-based screens" which reported that the current study examines urine samples from 66 subjects, comprising of 31 Urology clinic controls and 35 bladder cancer patients, using a Luminex based screening platform.

24 May 2021

Food dyes may cause disease when the immune system is dysregulated

Artificial food colorants can cause disease when the immune system has become dysregulated, Icahn School of Medicine at Mount Sinai researchers report.

14 May 2021

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

SARS-CoV-2 hijacks human cell machinery to disrupt the immune response, enabling it to cause infection, replicate, and cause disease.

4 May 2021

Study shows how WAVE2 protein maintains the immune system balance

Sinai Health researchers have reported that they have uncovered a new mechanism that regulates harmful overreactions in the body’s immune system.

26 Mar 2021

New label-free immune profiling assay to assess rapidly changing host immune response

Researchers from Critical Analytics for Manufacturing Personalized-Medicine (CAMP), an Interdisciplinary Research Group (IRG) at the Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, have developed a new label-free immune profiling assay that profiles the rapidly changing host immune response in case of infection, in a departure from existing methods that focus on detecting the pathogens themselves, which can often be at low levels within a host.

26 Mar 2021

Cytokine News and Research

Novel Assay Platform for 3D Microfluidic Cancer Research

Mast cell precursor cells get activated when exposed to allergic stimulation, shows study

Poor systemic immune responses and elevated MAIT cell activation linked to fatal COVID-19 infections

Scientists explore whether consuming cocoa can help us age better

Scientists develop lung organoids to imitate actual SARS-CoV-2 infection

Study uncovers key factors immune cells need to survive in the battle against cancer

Cytokines play a role in regulation of beige fat

Cells damaged by chronic lung disease favor SARS-CoV-2 entry

Study on memory T cells of COVID-19 convalescent patients could power effective vaccine strategies

New consortium of bacteria can be used to treat aggressive colitis in humanized mouse models

Novel drug is highly effective in preventing severe COVID-19 in mice

Study reveals urine protein biomarkers of bladder cancer

Food dyes may cause disease when the immune system is dysregulated

Study finds how SARS-CoV-2 hijacks human cell machinery to disrupt the immune response

Study shows how WAVE2 protein maintains the immune system balance

New label-free immune profiling assay to assess rapidly changing host immune response

Study shows how a subset of T cells is generated in melanoma survivors affected by vitiligo

Novel vaccine uses patient's own tumor cells to train the immune system to fight cancer

Study identifies new biomarkers for the prognosis of gastric adenocarcinoma

Machine learning approach to identify drugs that could be repurposed to fight Covid-19

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