Cytoplasm News and Research

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Scientists solve how RNA molecules reach their targets

Scientists claim that life does not come with an instruction manual, but this is not totally accurate. Each cell in our body follows the instructions provided by its DNA in the form of RNA molecules.

1 Aug 2022

Research reveals how two RNA-binding proteins interact with each other

Neurons are continually adapting to changing conditions. The biochemical basis for memory and learning is this plasticity.

5 Jul 2022

Researchers created ultrasound-guided microbubbles to enhance immunotherapy performance

The University of Texas MD Anderson Cancer Center scientists have created an ultrasound-guided cancer immunotherapy approach that promotes systemic antitumor immunity and increases immune checkpoint blockade therapeutic potential. Nature Nanotechnology published the results of the pioneering study.

1 Jun 2022

Little-known protein may play a role in frontotemporal lobar degeneration

Scientists have known for years that amyloid fibrils -; fibrous, ropelike structures formed by closely linked protein molecules -; are present in the brains of patients with Alzheimer's and Parkinson's diseases and likely play a role in the progression of these disorders.

21 Apr 2022

Researchers discover a mechanism by which the protein DELE1 detects organelle stress

Researchers have long speculated an association between disorders in mitochondria, tiny organelles inside the cell, and the aging process and age-related illnesses.

11 Apr 2022

Study shows how shuttle proteins safeguard the nuclear pores

The nucleus is guarded by a highly secure door, the so-called nuclear pore, that controls the transport of substances from the cytoplasm to the cell nucleus and back.

1 Feb 2022

New finding could lead to the development of cell death regulators for cancer therapies

Scientists led by Professor Ana J. Garcia-Saez at the CECAD Cluster of Excellence for Aging Research at the University of Cologne have shown that apoptosis, the programmed cell death, involves a direct physical interplay between the two proteins BAX and DRP1.

17 Jan 2022

Study finds amphipathic peptide that safely opens endosomal membrane

The cell plasma membrane and the derived endosomal membranes are both greasy barriers that prevent the inflow of water-soluble macromolecules like nucleic acids and proteins into cells.

2 Dec 2021

Infection with measles virus activates two different immune responses

Researchers from The University of Tokyo Institute of Industrial Science have found that infection with the measles virus activates not one but two different branches of the innate immune system.

15 Oct 2021

Tumor suppressor protein binding to RNA also binds DNA, says study

Scientists from the Medical University of South Carolina earlier displayed how hnRNP E1 attaches to metastatic-linked RNAs to prevent their translation.

27 Sep 2021

Experts decode the genetic mechanism governing the speed of mRNA translation

The genetic material of all eukaryotic organisms is stored in the cell nucleus in the form of DNA. The DNA is first transcribed into messenger RNA in the cell cytoplasm and later translated into protein using ribosomes for it to be used, where ribosomes are small machines capable of decoding messenger RNA to synthesize the relevant proteins.

1 Sep 2021

Researchers devise a new method for safer delivery of RNA drugs

Scientists have developed and tested a library of lipid-based compounds for the safe and effective delivery of RNA drugs to the lungs.

3 Aug 2021

New study could help develop novel treatments for neurodegenerative diseases

Researchers have introduced a novel gene therapy program that could set the stage for new treatments for neurodegenerative diseases.

2 Aug 2021

Researchers employ 3D holographic microscopy to visualize bioplastic in living cells

Scientists from KAIST inspected the accumulation of bioplastic granules in living bacterial cells with the help of 3D holographic microscopy.

29 Jul 2021

Study unravels gene expression control mechanism with immunity and cancer implications

Despite alternative polyadenylation (APA) affecting a larger part of human genes, the importance of APA was not well understood.

21 Jul 2021

Research substantiates nanoparticles as promising platforms for cell nano-sensors

Researchers published an article that represents the transmission electron microscopy (TEM) and flow cytometry study of A-549 (human lung carcinoma) cellular uptake of Pr3+:LaF3 nanoparticles.

21 Jul 2021

Brainless slime mold uses its body to sense mechanical cues in the environment

If you didn't have a brain, could you still figure out where you were and navigate your surroundings? Thanks to new research on slime molds, the answer may be "yes."

15 Jul 2021

Researchers identify a novel pathomechanism leading to Usher syndrome

Human Usher syndrome (USH) is the most common form of hereditary deaf-blindness. Sufferers can be deaf from birth, suffer from balance disorders, and eventually lose their eyesight as the disease progresses.

12 Jul 2021

Study reveals how cells “read” synthetic ingredients added to a genetic code

If the genome is considered the recipe for life, then base pairs represent the individual ingredients. DNA is made up of these chemical structures, and every living thing on the planet has just four of them.

21 Jun 2021

New “phase separation” protects against premature aging, neurological disorders

According to a new study, a mechanism through which an RNA, called NORAD, drives the Pumilio protein to create liquid droplets in cells—similar to oil in water—appears to closely control the activity of this protein.

11 Jun 2021