DNA Damage News and Research

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DNA damage and repair jointly shape mutational signatures

A collaborative project between the Center for Genome Integrity, within the Institute for Basic Science, and the Dundee School of Life Sciences, the EMBL's European Bioinformatics Institute, and the Wellcome Sanger Institute have screened almost 163,000 DNA mutations in 2,700 C. elegans roundworms to shed light on DNA damage.

9 Jun 2020

Genome rewiring could help explain evolution of multi-cellular organisms

InsideOutBio expert Dr Alan Herbert has explained a pioneering research in a paper recently published online by the Royal Society Open Science journal.

9 Jun 2020

C19ORF57 gene could advance reproductive medicine

The gene C19ORF57 has been identified to play a major role in meiosis by the Institute of Molecular Embryology and Genetics at Kumamoto University.

5 Jun 2020

Study demonstrates the role of p53 gene in cell cycle regulation and apoptosis

The p53 gene is crucial in cell biology and thus cell replacement therapy. The function of this gene is to control the cell cycle and stop tumor formation.

2 Jun 2020

Mechanically rejuvenated fibroblasts show promise in stem cell engineering

Fibroblasts synthesize the collagen, creating the structural framework for animal tissues, and play a significant role in the process of wound healing.

27 May 2020

New sequencing method helps map the spatial arrangement of DNA

A sequencing technique helps to map the spatial arrangement of DNA in the cell nucleus, revealing which regions of the genome are at greater risk of mutation.

27 May 2020

Aging neurons build up DNA damage, study finds

MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions.

18 May 2020

Stem cell research may improve regenerative medicine

A new study has provided new insight into the mechanisms that cause mutations in pluripotent stem cells, offering potential ways for preventing mutations.

18 May 2020

Study reveals proteins that sustain cancer cells

Scientists from the University of Copenhagen have identified two major functions of the protein known as RTEL1 during cell division, in a recently performed study.

14 May 2020

Infrared spectroscopy reveals DNA molecular processes in real time

DNA strand breaks can play a role in the aging process. Now, with infrared spectroscopy, scientists have visualized the processes that take place at breaks.

4 May 2020

Study shows how mutational signatures are shaped by DNA repair pathways

A research team has examined more than 2700 genomes from C. elegans worms to gain a better understanding on the causes responsible for mutations.

4 May 2020

DNA Damage And Faulty Repair Jointly Cause Mutations

Researchers at EMBL-EBI analyzed over 2700 genomes from C. elegans worms in order to better understand the causes of mutations.

4 May 2020

Impaired cell division is linked to cancer

The body replaces aging and damaged cells by mainly using a process known as mitosis, wherein a single cell splits into two cells.

30 Apr 2020

Scientists Recreate DNA Damage Caused By Toxins From Smoking

Researchers from the University of York have recreated how toxins from smoking cause unique patterns of DNA damage.

29 Apr 2020

Scientists discover how tissues protect their DNA from mechanical stress

In everyday life, our tissues, for example skin and muscle, are stretched, pulled and compressed without causing damage to the cells or the DNA.

24 Apr 2020

Study shows promise for treating different types of cancer

This story looks into the potential to treat various types of cancers using cells and the process of apoptosis.

7 Apr 2020

Study reveals key mechanism behind DNA repair processes

According to a study recently published in the eLife journal, researchers have demonstrated a crucial mechanism involved in the repair processes of DNA double-strand breaks.

25 Mar 2020

Zscan4 protein protects against deadly DNA damage during early embryonic development

In association with Stanford University, a working group from the Division of Cell and Developmental Biology at the Medical University of Vienna (MedUni Vienna) has discovered the role of a crucial factor that plays a role in early embryonic development.

23 Mar 2020