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Anti-idiotype antibodies may explain the long-term effects of COVID-19

With around 256 million cases and more than 5 million deaths worldwide, the COVID-19 pandemic has challenged scientists and those in the medical field. Researchers are working to find effective vaccines and therapies, as well as understand the long-term effects of the infection.

From The University of California, Davis 26 Nov 2021

Researchers test a neoantigen-specific transgenic immune cell therapy for malignant gliomas

Doctors and scientists from the German Cancer Research Center (DKFZ) and from Heidelberg University's Medical Faculty Mannheim have successfully tested a neoantigen-specific transgenic immune cell therapy for malignant brain tumors for the first time using an experimental model in mice.

16 Nov 2021

Transformative technology aims to provide insights into the function of immune cells

Immunotherapy has revolutionized cancer treatment and it is not an overstatement.

8 Nov 2021

Blood metabolite levels altered by coffee consumption and may affect chronic kidney disease risk

Food and beverages may have important effects on kidney health, but the potential biological mechanisms involved are often unclear.

5 Nov 2021

Targeted drug shows promise against brain metastases from kidney cancer

A targeted drug has shown promising activity against brain metastases resulting from kidney cancer, achieving a 50 percent response rate, and supporting further studies of the drug in this patient group whose poor prognosis has created a significant unmet need.

22 Oct 2021

Experts develop antibodies that effectively remove senescent cells

The reason why some people age worse than others and develop diseases linked to the aging mechanism is largely unknown.

22 Oct 2021

Diagnostic value of SARS-CoV-2 specific T cell immune responses may be limited

Can T-cell tests be used to determine whether people have had COVID-19? Scientists at Uppsala University and Karolinska Institutet have jointly analysed this issue under the aegis of the COMMUNITY study at Danderyd Hospital. Their study is published in the scientific journal PLOS ONE.

5 Oct 2021

Polygenic risk scores are no better in predicting disease, says study

Scientists went through the records of more than 8,000 schizophrenia patients and identified a tool used for assessing an individual’s genetic risk for a disease.

8 Sep 2021

Genetically engineered cells deliver drugs in response to inflammation

With a goal of developing rheumatoid arthritis therapies with minimal side effects, researchers at Washington University School of Medicine in St. Louis have genetically engineered cells that, when implanted in mice, will deliver a biologic drug in response to inflammation.

2 Sep 2021

Acoustics solutions based on cellulose fibers can reduce carbon footprint of buildings

Good acoustics in the workspace improve work efficiency and productivity, which is one of the reasons why acoustic materials matter. The acoustic insulation market is already expected to hit 15 billion USD by 2022 as construction firms and industry pay more attention to sound environments.

3 Jun 2021

3D biomaterial helps implanted stem cells stick around to reverse arthritis

A 3D biomaterial scaffold design to slowly release stem cells has worked to ensure implanted stem cells stick around to relieve pain and reverse arthritis in mice knee joints.

19 Apr 2021

Novel test detects HIV reservoir in patients more accurately

An innovative test that determines the quality and quantity of inactive HIV viruses in the genes of HIV patients may ultimately give scientists a better idea of effective drugs.

14 Apr 2021

Study finds the brain is changed by caffeine in utero

New research finds caffeine consumed during pregnancy can change important brain pathways that could lead to behavioral problems later in life.

10 Feb 2021

Scientists modify toxic pesticide to treat antibiotic-resistant bacteria

A significant class of heterocyclic compounds, called N-Aryl-C-nitroazoles, is used as fungicides and pesticides. But these substances could be harmful to human beings and cause mutations.

4 Jan 2021

Study identifies the effects of nutritional deficiency on patient survival after cardiac surgery

Nutrients are the structural components of food that the body needs to function properly. They are divided into macronutrients (proteins, fats, carbohydrates) and micronutrients (vitamins, provitamins, various minerals, and so on). Their shortage is called nutritional deficiency.

4 Jan 2021

CSIRO identifies coastal 'bright spots' to repair marine ecosystems

CSIRO, Australia's national science agency, has identified coastal 'bright spots' to repair marine ecosystems globally, paving the way to boost biodiversity, local economies, and human wellbeing.

22 Dec 2020

Changes to oral microbiota affect the cardiovascular benefits of sport

Exercise plays a key role in maintaining good physical and mental health throughout life. There is an increasing amount of scientific evidence that some of the immune system and metabolism benefits provided by sport are related to the thousands of millions of bacteria that colonize the digestive tract, from the mouth to the intestines, known as microbiota.

10 Dec 2020

Tumor DNA in DLBCL patient's stem cells or blood can predict risk of relapse after transplant

Many patients with diffuse large B-cell lymphoma (DLBCL) can be cured by a transplant using their own blood-forming stem cells, but as many as half eventually relapse. New research led by Dana-Farber Cancer Institute scientists suggests that patients whose blood or stem cell samples harbor tumor DNA are likely to relapse.

8 Dec 2020

CAR T-cell therapy reduced cancer cells in patients with advanced non-Hodgkin lymphoma

A CAR T-cell therapy known as axicabtagene ciloleucel (axi-cel) drove cancer cells to undetectable levels in nearly 80% of patients with advanced non-Hodgkin lymphoma (NHL) in a phase 2 clinical trial, Dana-Farber Cancer Institute investigators report at the virtual 62nd American Society of Hematology (ASH) Annual Meeting.

7 Dec 2020

Scientists reveal health benefits of clonal hematopoiesis in allogeneic transplants

Clonal hematopoiesis (CH) is a recently identified condition in which mutations associated with blood cancers are detected in the blood of some healthy, usually older, individuals who don't have cancer. People with CH, while asymptomatic, have an elevated risk of developing blood cancers and other negative health outcomes, including heart attacks and strokes.