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Breast cancer-on-a-chip for rapid screening of immunotherapeutic drugs

There are many mechanisms by which the body responds to foreign invaders. One of these involves the T-cells of the immune system, which have a number of different proteins on their surface called "checkpoint proteins."

3 Feb 2021

Study discovers new anti-inflammatory role for well-known blood clot protein

Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases.

2 Feb 2021

Genetic changes in tumors could help predict patient's response to immunotherapy drugs

Researchers at the Francis Crick Institute, the UCL Cancer Institute, and the Cancer Research UK Lung Cancer Centre of Excellence have identified genetic changes in tumours which could be used to predict if immunotherapy drugs would be effective in individual patients.

28 Jan 2021

Researchers identify a new compound for creating a new class of diabetes drugs

A new study headed by the Ohio State University Wexner Medical Center and the College of Medicine has found a new compound that could form the base for creating a new class of diabetes drugs.

28 Jan 2021

Study shows how abnormal number of chromosomes could become a weak point for cancer cells

What makes cancer cells different from ordinary cells in our bodies? Can these differences be used to strike at them and paralyze their activity?

28 Jan 2021

Researchers develop a method to simultaneously measure 77 antibiotics in foods

Widespread use of antibiotics in human healthcare and livestock husbandry has led to trace amounts of the drugs ending up in food products.

28 Jan 2021

New technique replicates bone tissue complexity and bone remodeling processes

A multidisciplinary team of researchers at the University of Massachusetts Amherst's Institute for Applied Life Sciences (IALS) have developed a technique to replicate bone tissue complexity and bone remodeling processes.

27 Jan 2021

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

A world-first discovery by researchers at Monash University and The University of Queensland could lead to faster and more effective treatments for chronic health complications, such as cardiovascular disease and cancer, with 'fluorescent' in vivo biosensors.

27 Jan 2021

Anchor proteins inhibit a key metabolic driver involved in cancer and neuronal diseases

Certain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders.

27 Jan 2021

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

According to a new study, non-steroidal anti-inflammatory drugs (NSAIDs) decreased both inflammatory and antibody responses to SARS-CoV-2 infection in mice.

26 Jan 2021

Cancer cells can exchange and recombine their genetic material, shows study

Evolution within groups of tumor cells follows the principles of natural selection, as evolution in pathogenic microbes.

22 Jan 2021

SARS-CoV-2 virus may enter and replicate in human cells by targeting cellular processes

The SARS-CoV-2 virus may enter and replicate in human cells by exploiting newly-identified sequences within cell receptors, according to work from two teams of scientists.

22 Jan 2021

Researchers identify a new way to stop COVID-19 virus

While the world awaits broad distribution of COVID-19 vaccines, researchers at Ohio University just published highly significant and timely results in the search for another way to stop the virus -- by disrupting its RNA and its ability to reproduce.

22 Jan 2021

Venom of Tiger Rattlesnakes may advance genetic science

Among all rattlesnake species, the Tiger Rattlesnake has the simplest yet most lethal venom. Now, a new study performed by a team of researchers can describe the genetics behind the venomous bite of the Tiger Rattlesnake.

21 Jan 2021

Common insecticides affect the amount of night's sleep in bumblebees and fruit flies

Just like us, many insects need a decent night's sleep to function properly, but this might not be possible if they have been exposed to neonicotinoid insecticides, the most common form of insecticide used worldwide, suggests research by academics at the University of Bristol.

21 Jan 2021

Investigational antisense medicine lowers disease burden, reduces myeloma cell abundance in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease -- cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back.

From UC San Diego 21 Jan 2021

Researchers define cancer invasion machinery orchestrated by cancer gene

Researchers at the University of Helsinki have defined a cancer invasion machinery, which is orchestrated by a frequently mutated cancer gene called Ras. When signaling from Ras protein becomes abnormally high, like it does in many cancers, this switches on the cellular machinery that helps the cancer cells to depart from the tissue from which the cells have developed.

20 Jan 2021

Drugs News and Research

Breast cancer-on-a-chip for rapid screening of immunotherapeutic drugs

Study discovers new anti-inflammatory role for well-known blood clot protein

Genetic changes in tumors could help predict patient's response to immunotherapy drugs

Researchers identify a new compound for creating a new class of diabetes drugs

Study shows how abnormal number of chromosomes could become a weak point for cancer cells

Researchers develop a method to simultaneously measure 77 antibiotics in foods

New technique replicates bone tissue complexity and bone remodeling processes

Continuous in vitro monitoring could lead to faster, more effective treatments for chronic conditions

Anchor proteins inhibit a key metabolic driver involved in cancer and neuronal diseases

Non-steroidal anti-inflammatory drugs reduce antibody and inflammatory responses to COVID-19

Cancer cells can exchange and recombine their genetic material, shows study

SARS-CoV-2 virus may enter and replicate in human cells by targeting cellular processes

Researchers identify a new way to stop COVID-19 virus

Venom of Tiger Rattlesnakes may advance genetic science

Common insecticides affect the amount of night's sleep in bumblebees and fruit flies

Investigational antisense medicine lowers disease burden, reduces myeloma cell abundance in mice

Researchers define cancer invasion machinery orchestrated by cancer gene

New method shows how pharmaceuticals induce cancer cell death

Researchers develop more effective personalized immunotherapy for cancer patients

Targeting RNA splicing can trigger antiviral immune pathways in triple-negative breast cancers

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