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Identifying How a Particular Riboswitch Regulates its Synthesis

Researchers across the world are in search of ways to combat bacteria that could evade the present arsenal of antibiotics. This is done as a measure to avoid a global health crisis.

2 Jun 2023

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.

2 Jun 2023

Scientists Integrate Multiple Therapeutic Approaches to More Effectively Target Brain Metastatic Melanomas

Acting as a team, twin stem cells activate the immune system to suppress tumor growth and prolong survival in representative preclinical models.

1 Jun 2023

New Insight Into Cellular Waste Disposal Process

To prevent our body's cells from overflowing with garbage and to keep them healthy, the waste inside them is constantly being disposed of.

25 May 2023

Breakthrough Discovery Paves Way for Understanding Downstream Cellular Applications in Human Health

Assemblies of tiny molecular proteins span the membranes that encapsulate our cells, directing cellular activities and regulating the transport of materials and information in and out.

25 May 2023

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Inflammatory fatty liver disease (NASH, non alcoholic steatohepatitis ) and the resulting liver cancer are driven by autoaggressive T cells. Scientists from the German Cancer Research Center (DKFZ) now show what ist behind this destructive behavior. I

24 May 2023

Researchers Elucidate the Exact Mechanism of Cell Death

24 May 2023

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Antiretroviral cocktails can make human immunodeficiency virus, or HIV, undetectable and untransmittable, but both the virus and its treatment can also accelerate aging of bone and muscle.

24 May 2023

Altered Anti-Nausea Drug can Penetrate Cells and Provide Sustained Pain Relief

Altering the chemical properties of an anti-nausea drug enables it to enter an interior compartment of the cell and provide long-lasting pain relief, according to a new study led by researchers at NYU College of Dentistry's Pain Research Center.

23 May 2023

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Enzymes are the molecule factories in biological cells. However, which basic molecular building blocks they use to assemble target molecules is often unknown and difficult to measure.

23 May 2023

Key Event that Controls the Timing of the Biological Clock Identified

Molecular clocks in our cells synchronize our bodies with the cycle of night and day, cue us for sleep and waking, and drive daily cycles in virtually every aspect of our physiology. Scientists studying the molecular mechanisms of our biological clocks have now identified a key event that controls the timing of the clock.

23 May 2023

New Insights into the Final Step of Cell Death

Every day, millions of cells die in our body. Other than generally assumed, cells do not simply burst at the end of their lives but rather, a specific protein serves as a breaking point for cell membrane rupture. Researchers at the University of Basel have now been able to elucidate the exact mechanism at the atomic level. They have published their results in Nature.

23 May 2023

Compound Found in Magnolia Tree Bark Inhibits SARS-CoV-2 Replication in Several Cell Types

A compound called honokiol, which is found in the bark of multiple species of magnolia tree, inhibits replication of SARS-CoV-2 virus in several types of cells, according to a team of researchers in the Netherlands.

23 May 2023

TTUHSC Professor Awarded NIH Grant for Potassium Channel Study

Each living cell has small, highly specialized conduits called potassium (K+) channels, which are responsible for the highly selective and fast transfer of K+ ions across cell membranes.

19 May 2023

Predictive Models to Determine the Structure, Stability, Flexibility and Biology of RNA-Targeted Drugs

Proteins are large, complex molecules that play many critical roles in the body and are produced following the instructions encoded in DNA.

18 May 2023

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Researchers at the University of Michigan Rogel Cancer Center have discovered a new nutrient source that pancreatic cancer cells use to grow.

18 May 2023

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

The deadly hospital pathogen Acinetobacter baumannii can live for a year on a hospital wall without food and water. Then, when it infects a vulnerable patient, it resists antibiotics as well as the body's built-in infection-fighting response.

17 May 2023

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Researchers at the Josep Carreras Leukaemia Research Institute, led by Dr. Manel Esteller, have discovered a key epigenetic alteration that anticipates the clinical course of liver cancer.

17 May 2023

Single-Cell Omics Reveals Cell Types Involved in the Biosynthesis of Plant Natural Products

In a new study published in Nature Chemical Biology, an international team of researchers from the University of Georgia, USA, and the Max Planck Institute for Chemical Ecology in Jena, Germany, presents a promising strategy for elucidating metabolic pathways for plant compounds of medicinal importance.

16 May 2023

Study Finds Methylated CD Derivatives as Effective Stabilizers for Supersaturated Drugs

In the medicine market, most newly introduced drugs and drug candidates show poor water solubility, which prevents their absorption in the body. This, in turn, limits their therapeutic efficiency.

16 May 2023

Drugs News and Research

Identifying How a Particular Riboswitch Regulates its Synthesis

Antioxidant Enzymes Relocate to the Nucleus in Response to DNA Damage

Scientists Integrate Multiple Therapeutic Approaches to More Effectively Target Brain Metastatic Melanomas

New Insight Into Cellular Waste Disposal Process

Breakthrough Discovery Paves Way for Understanding Downstream Cellular Applications in Human Health

Activated B Cells in Gastrointestinal Tract Contribute to the Development of Liver Cancer

Researchers Elucidate the Exact Mechanism of Cell Death

Identifying Drugs to Put the Brakes On Accelerated Aging From HIV Infection, Treatment

Altered Anti-Nausea Drug can Penetrate Cells and Provide Sustained Pain Relief

Researchers Develop AI Method to Predict Small Molecule Substrates of Enzymes

Key Event that Controls the Timing of the Biological Clock Identified

New Insights into the Final Step of Cell Death

Compound Found in Magnolia Tree Bark Inhibits SARS-CoV-2 Replication in Several Cell Types

TTUHSC Professor Awarded NIH Grant for Potassium Channel Study

Predictive Models to Determine the Structure, Stability, Flexibility and Biology of RNA-Targeted Drugs

Pancreatic Cancer Cells Use a New Nutrient Source to Grow, Study Finds

Researchers Discover How Deadly Hospital Pathogen can Survive Harsh Environments

Liver Cancers With Key Epigenetic Alteration Tend to Have a Poor Clinical Prognosis

Single-Cell Omics Reveals Cell Types Involved in the Biosynthesis of Plant Natural Products

Study Finds Methylated CD Derivatives as Effective Stabilizers for Supersaturated Drugs

CITES: Regulating the International Wildlife Trade to Preserve the Viability of Species

How can the adoption of AI technology accelerate drug discovery?

Gaining insights into human disease biology through CRISPR platforms

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