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Changes in glioblastoma cells influence the effect of different drugs, shows study

Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways.

15 Jul 2020

New study can help develop novel drugs for prostate cancer

The androgen receptor is considered the main driver of the growth and initiation of prostate cancer, which is known to be the second-leading cause of death in men.

15 Jul 2020

Umbilical cord blood treats children born with non-cancerous genetic disorders

Researchers at UPMC Children's Hospital of Pittsburgh found that infusing umbilical cord blood -- a readily available source of stem cells -- safely and effectively treated 44 children born with various non-cancerous genetic disorders, including sickle cell, thalassemia, Hunter syndrome, Krabbe disease, metachromatic leukodystrophy (MLD) and an array of immune deficiencies.

15 Jul 2020

Stem cell treatment could improve the quality of donor kidneys

New research has demonstrated that kidneys can be revived prior to transplantation by delivering a cell therapy directly to the organ.

From Newcastle University 15 Jul 2020

Fewer but larger doses of radiotherapy are safe for patients with early breast cancer

A lower total dose of radiotherapy delivered in fewer but larger doses is as safe in the long term as breast cancer radiotherapy courses giving multiple small doses, according to the final results of a 10-year study.

15 Jul 2020

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

Chronic lymphocytic leukemia (CLL) is the most common leukemia in adults. One in four new leukemia cases are CLL.

15 Jul 2020

UTMB researchers uncover new mechanism for designing dengue therapeutics

A multidisciplinary team from The University of Texas Medical Branch at Galveston has uncovered a new mechanism for designing antiviral drugs for dengue virus. The study is currently available in Proceedings of the National Academy of Sciences.

14 Jul 2020

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

New immunotherapy developed by researchers at Northwestern University dramatically extends the survival time of mice with triple-negative breast cancer, one of the most aggressive and difficult-to-treat forms of breast cancer.

14 Jul 2020

Researchers test the efficiency of F2X Entry library to expedite the quest for active compounds

For drugs to be effective, they usually have to dock to proteins in the organism. Like a key in a lock, part of the drug molecule must fit into recesses or cavities of the target protein.

14 Jul 2020

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Scientists at the Walter Reed Army Institute for Research (WRAIR) have recently demonstrated that cathepsin B, a well-studied protein important to brain development and function, can be used as biomarker, or indicator of severity, for traumatic brain injury.

14 Jul 2020

Less addictive opioid may have the ability to slow progression of osteoarthritis

A novel preclinical study by Keck Medicine of USC researchers, published in Arthritis & Rheumatology, reveals that a potential new opioid medication may have the ability to slow the progression of osteoarthritis while being less addictive than commonly prescribed opioid drugs.

14 Jul 2020

Researchers evaluate role of zinc in COVID-19 prevention

Researchers from Sechenov University in collaboration with colleagues from Germany, Greece and Russia reviewed scientific articles on the role of zinc in the prevention and treatment of viral infections and pneumonia, with projections on those caused by SARS-CoV-2. The results were published in the International Journal of Molecular Medicine.

14 Jul 2020

Common molecular feature in SARS-CoV-2 neutralizing antibodies discovered

A team led by scientists at Scripps Research has discovered a common molecular feature found in many of the human antibodies that neutralize SARS-CoV-2, the coronavirus that causes COVID-19.

14 Jul 2020

Brain's response to alcohol varies based on individual preferences, rat study shows

The brain's response to alcohol varies based on individual preferences, according to new research in rats published in eNeuro.

14 Jul 2020

Researchers use DSC-based method to measure protein-ligand binding

A team of researchers from Kazan Federal University, Russia, led by Dr. Igor Sedov, reported an application of capillary differential scanning calorimetry technique for the study of the binding of albumin, a plasma transport protein, with different drug ligands.

14 Jul 2020

Compound in pickled capers can activate proteins required for bodily processes

A compound commonly found in pickled capers has been shown to activate proteins required for normal human brain and heart activity, and may even lead to future therapies for the treatment of epilepsy and abnormal heart rhythms.

14 Jul 2020

New technology generates immune response by delivering antigens to APCs in the spleen

Red blood cells do more than shuttle oxygen from our lungs to our organs: they also help the body fight off infections by capturing pathogens on their surfaces, neutralizing them, and presenting them to immune cells in the spleen and liver.

14 Jul 2020

Study shows a causal link between individual microbiota and survival of antibiotic-resistant bacteria

Antibiotic resistance is a growing challenge in the treatment of infectious diseases worldwide. Bacteria become resistant to antibiotics by acquiring or mutating genes that allow them to survive the administration of antibiotics, which otherwise would kill them.

14 Jul 2020

Study identifies brain cells that control sugar intake and cravings

New research has identified the specific brain cells that control how much sugar you eat and how much you crave sweet tasting food.

13 Jul 2020

Genomics study in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

13 Jul 2020

Drugs News and Research

Changes in glioblastoma cells influence the effect of different drugs, shows study

New study can help develop novel drugs for prostate cancer

Umbilical cord blood treats children born with non-cancerous genetic disorders

Stem cell treatment could improve the quality of donor kidneys

Fewer but larger doses of radiotherapy are safe for patients with early breast cancer

Dual inhibitor therapy may be safer for patients with chronic lymphocytic leukemia

UTMB researchers uncover new mechanism for designing dengue therapeutics

Researchers develop new immunotherapy that prevents reoccurrence of breast cancer

Researchers test the efficiency of F2X Entry library to expedite the quest for active compounds

Study shows cathepsin B can be used as biomarker for traumatic brain injury

Less addictive opioid may have the ability to slow progression of osteoarthritis

Researchers evaluate role of zinc in COVID-19 prevention

Common molecular feature in SARS-CoV-2 neutralizing antibodies discovered

Brain's response to alcohol varies based on individual preferences, rat study shows

Researchers use DSC-based method to measure protein-ligand binding

Compound in pickled capers can activate proteins required for bodily processes

New technology generates immune response by delivering antigens to APCs in the spleen

Study shows a causal link between individual microbiota and survival of antibiotic-resistant bacteria

Study identifies brain cells that control sugar intake and cravings

Genomics study in Black Americans could lead to precision prostate cancer therapies

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