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gnomAD Consortium releases first set of discoveries on human genetic variation

For the last eight years, the Genome Aggregation Database Consortium (and its predecessor, the Exome Aggregation Consortium, or ExAC), has been working with geneticists around the world to compile and study more than 125,000 exomes and 15,000 whole genomes from populations around the world.

29 May 2020

Research project launched to find new treatments for rare genetic diseases

The University Carlos III Madrid, Almirall, S.A. and the MEDINA Foundation have launched a project to find new treatments for recessive dystrophic epidermolysis bullosa and other genetic diseases caused by nonsense mutations.

29 May 2020

Study identifies potent neutralizing antibodies against SARS-CoV-2

A joint research team led by Sunney Xie, Director of Beijing Advanced Innovation Center for Genomics at Peking University has successfully identified multiple highly potent neutralizing antibodies against the novel coronavirus SARS-CoV-2, the causative virus of the respiratory disease COVID-19, from convalescent plasma by high-throughput single-cell sequencing.

29 May 2020

Study provides new strategies for treating different types of cancer

An RNA molecule involved in preventing the formation of tumors can modify its structure and thus regulate the production of proteins in the cell.

29 May 2020

New technique enables high-resolution visualization of tumor heterogeneity patterns

Malignant tumors consume nutrients and oxygen faster than healthy cells. To do so, they recruit blood vessels in their environment.

28 May 2020

Making opioids safer and more effective

Dr. John Streicher speaks to AZoLifeSciences about his research on improving opioid drugs to make them safer and more effective.

From University of Arizona 28 May 2020

New minimally invasive method allows cells to be sampled over time

At any given moment, a variety of dynamic processes occur inside a cell, with many developing over time. Because current research methods for gene profiling or protein analysis destroy the cell, study is confined to just that one moment in time, and researchers are unable to return to the cell to examine how things change beyond that snapshot.

27 May 2020

Researchers design antibody to identify pathogens of Alzheimer's disease

Researchers have found a way to design an antibody that can identify the toxic particles that destroy healthy brain cells - a potential advance in the fight against Alzheimer's disease.

26 May 2020

Compounds in Brazilian shrub can reduce the virulence of antibiotic-resistant bacteria

Researchers have discovered that the Brazilian peppertree—an invasive, weedy shrub found in Florida—contains specific compounds that lower the virulence of Staphylococcus bacteria that are resistant to antibiotics.

25 May 2020

Biochemical and computational methods for large-scale protein-arginine methylation analysis

Methylation (namely addition of a methyl group) of arginine amino acid residues of proteins is a post-translational modification (PTM) catalyzed by a family of nine enzymes called Protein Arginine Methyl-Transferases (PRMTs).

23 May 2020

Nanobowl-stabilized liposomes are less leaky than regular liposomes

For many years, researchers have analyzed the use of liposomes, which are hollow spheres composed of lipid bilayers, to transmit chemotherapy drugs to tumor cells.

22 May 2020

Study shows senotherapy blunts the progression of liver tumors

According to a new study performed by researchers, “senotherapy” blunts the progression of liver tumor in animal models.

22 May 2020

Scientists develop novel model of liver cancer stem cells from normal iPSCs

Liver cancer is one of the deadliest cancers. It is insidious and does not present symptoms until it has progressed considerably, at which point, treatment options are limited and chances of survival are low. The most common type of liver cancer is hepatocellular carcinoma.

22 May 2020