Embryonic Stem Cells News and Research

RSS

USC Scientists Discover Protein Key to 3D Genome Control and Gene Silencing

Each cell’s nucleus contains DNA, which is the blueprint for human life.

17 Jan 2024

Japanese Scientists Revolutionize Regenerative Lung Medicine

Globally, chronic obstructive pulmonary disease, or COPD, is the third most common cause of mortality. It is characterized by permanent and irreversible lung damage, for which lung transplantation is the only effective treatment. Unfortunately, it is hard to find good lung donors.

8 Jan 2024

Wilmot Researchers Uncover a "Genomic Tug of War" That Influences Decitabine's Effectiveness

Some patients with myelodysplastic syndromes, like acute myeloid leukemia, benefit from a chemotherapy drug called decitabine that stunts cancer growth. But many others are resistant to decatibine's effects or become resistant over time.

17 Nov 2023

DNA Aptamer Promotes Cardiomyocyte Differentiation From Pluripotent Stem Cells

Generating specific cell lineages from induced pluripotent stem cells and embryonic stem cells is the holy grail of regenerative medicine.

12 Oct 2023

Towards A Better Understanding of Early Human Embryonic Development

Despite being an essential developmental process, the understanding of human embryonic genome activation is limited, owing to the lack of in vitro cell models and ethical concerns.

22 Sep 2023

How Scientists are Using iPSCs to Develop New Therapies

In 1998, scientists reported being able to derive cells from human embryos that could develop into almost any cell in the body. In 2007, the field took a huge leap when scientists discovered they could reprogram human adult skin cells to act like these embryonic stem cells.

20 Sep 2023

Reprogramming Human Cells to Mimic Embryonic Stem Cells

Australian scientists have overcome a long-standing challenge in regenerative medicine in a remarkable discovery published in Nature.

17 Aug 2023

The Function of Stem Cell Barriers in the Treatment of Fertility

A set of molecules controls cells as they proliferate and take on certain identities and spatial placements within a human embryo as it develops.

18 Jul 2023

New Study Identifies Aerobic Glycolysis Vital for Eye Development

According to a recent Northwestern Medicine study published in Nature Communications, aerobic glycolysis, the process by which cells convert glucose into lactate, is essential for eye development in mammals.

17 Jul 2023

Trim24 Limits the Ability of p53 to Function as a Tumor Suppressor

The tumor suppressor protein p53 has been nicknamed the “guardian of the genome” because it safeguards the DNA from long-term damage or stress by controlling the expression of numerous genes involved in DNA repair, cell division, and cell death.

3 Jul 2023

Stem Cell Zoo Uncovers Scaling Laws Governing Species-Specific Development

Pregnancy last around nine months in humans, only 20 days in mice, and up to 17 months in rhinoceroses. Even though many mammalian species go through the same phases of embryo development, the rate of development varies greatly between animals.

21 Jun 2023

Generation of Monkey Blastoids Using Optimized Protocol

Human embryo development and early organ development remain unclear due to ethical concerns about using embryos for research and a scarcity of materials to investigate.

7 Apr 2023

BetaLife and A*STAR team up to accelerate the development of new cell-based therapy for diabetes

Up-and-coming local biotech startup BetaLife Pte Ltd ("BetaLife") is collaborating with the Agency for Science, Technology and Research (A*STAR) to accelerate the development of next generation cell-based therapy for diabetes.

22 Mar 2023

DNA methylation for precise gene expression regulation

If the genome is viewed as a guidebook for how a cell should operate, then annotations, highlights, and bookmarks are included on every page.

21 Feb 2023

The detrimental effects of alcohol consumption during pregnancy

For the first time, researchers at the University of Helsinki in Finland examined the effects of prenatal alcohol exposure on the epigenome and gene function of the placenta. The epigenome is a molecular coating on a DNA strand that controls how genes are expressed.

4 Jan 2023

Revealing cancer development in people carrying inherited BRCA1 mutations

Researchers from Weill Cornell Medicine have discovered that people who inherit a mutant copy of the BRCA1 gene may develop mutations and cancer due to error-prone DNA replication and repair.

16 Nov 2022

Researchers reveal key developmental difference between the brains of modern humans and Neanderthals

AZoLifesciences speaks to Dr. Anneline Pinson and Prof. Dr. Wieland B. Huttner from The Max Planck Institute of Molecular Cell Biology and Genetics about their latest research which found a greater neuron production in the frontal lobe during brain development in modern humans than Neanderthals, due to the change of a single amino acid in the protein TKTL1.

From The Max Planck Institute 20 Sep 2022