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Single-Cell Sequencing Sheds Light on Breast Cancer Genetics

Research reveals somatic copy number alterations in breast epithelial cells, linking early genetic changes to cancer development and highlighting BRCA1/2 roles.

29 Nov 2024

The Role of RNA Polymerase and Ribosomes in Gene Expression

DNA within a cell contains the genetic instructions necessary for building proteins.

29 Nov 2024

Unmasking the Molecular Mechanisms of Melanoma

LMU researchers have discovered how the interplay between a key protein and an endolysosomal ion channel promotes tumor development in skin cancer.

24 Nov 2024

Scientists Use Cell Density to Control Tissue Formation

Genes aren't the sole driver instructing cells to build multicellular structures, tissues, and organs.

20 Nov 2024

Magnesium-Focused Approach to Curbing Antibiotic Resistance

According to recent estimates, the number of fatal antibiotic-resistant illnesses is expected to increase significantly over the next 25 years.

18 Nov 2024

New Bioluminescent Proteins Enable Excitation-Free Imaging in Living Organisms

Bioluminescence is the natural chemical process of light creation in some living creatures that makes fireflies flicker and some jellyfish glow.

14 Nov 2024

3D Tumor Microenvironment Model Highlights Role of Ischemia and Acidification in Cancer Spread

Developed 3MIC model simulates tumor microenvironments, enabling direct observation of ischemic effects on cancer cell invasiveness and drug resistance.

4 Nov 2024

Discover Photon etc.'s latest innovation: LightIR

Photon etc. announces the launch of its newest instrument, the LightIR system, designed for preclinical fluorescence imaging and clinical research.

From Photon etc. 31 Oct 2024

Research Sheds Light on Biofilm Bacteria Interactions and Competition

Biofilms -; slimy communities of bacteria -; grow on all sorts of surfaces: from glaciers and hot springs to plant roots, your bathtub and fridge, wounds, and medical devices such as catheters.

18 Oct 2024

Researchers Develop Fluorescent Biosensor to Study PKC Activity

Working in organoid models, researchers at University of California San Diego School of Medicine have developed a new tool to study protein-kinase C (PKC) enzymes, which play a critical role in cell growth, differentiation and survival.

14 Oct 2024

Uncovering Hidden Bacteria in Antibiotic Resistance

Imagine a country with a billion people, where every individual has different interests and different goals. You will never know their interests and goals until you ask them, but asking a billion people is not an easy task.

7 Oct 2024

Scientists Successfully Map the Entire Fruit Fly Brain

A team of scientists supported by the National Institutes of Health (NIH)'s The BRAIN Initiative, including Davi Bock, Ph.D., Associate Professor of Neurological Sciences at UVM's Robert Larner, M.D. College of Medicine, recently made a substantial advancement in neurobiological research by successfully mapping the entire brain of Drosophila melanogaster, more commonly known as the fruit fly.

3 Oct 2024

New Method Detects Peroxymonocarbonate and Its Role in Cellular Responses

High levels of carbon dioxide (CO2) in the atmosphere can alter not only the climate of our planet but also the functioning of our cells.

24 Sep 2024

A Novel Biosensor for Calcium Detection in Fruit Flies, Zebrafish, and Mice

In 2021, the Janelia group leaders reported that they had developed a way to combine Schreiter's engineered protein biosensors and Lavis's bright, fluorescent Janelia Fluor dyes.

23 Sep 2024

Scientists Develop Lab-Grown Muscle Stem Cells for Advanced Regenerative Therapies

Recent findings reveal that induced satellite cells can effectively regenerate muscle tissue, outperforming traditional myoblasts in engraftment and function.

23 Sep 2024

New Insights into How Mutant p53 Promotes Tumor Growth

Research from the Federal University of Rio de Janeiro (UFRJ) and the National Institute of Science and Technology for Structural Biology and Bioimaging (INBEB) in Brazil has uncovered a critical mechanism by which mutations in the p53 protein-;a key tumor suppressor known as the "guardian of the genome"-;turn other proteins into cancer-promoting agents

17 Sep 2024

Breakthrough Nanoparticle Therapy Boosts Immune Response Against Aggressive Pancreatic Cancer

Innovative use of lipid nanoparticles to deliver immune agonists shows promise in activating anti-tumor immunity in pancreatic ductal adenocarcinoma models.

9 Sep 2024

New SPARXS Technique Revolutionizes DNA Sequence Analysis

"DNA, RNA and proteins are the key players to regulate all processes in the cells of our body," Leiden Professor John van Noort explains. "To understand the (mis-)functioning of these molecules, it is essential to uncover how their 3D structure depends on their sequence and for this it is necessary to measure them one molecule at a time. However, single-molecule measurements are laborious and slow, and the number of possible sequence variations is massive."

23 Aug 2024

New Imaging Technique Offers Clearer View of Brain Function

Researchers have developed a new two-photon fluorescence microscope that captures high-speed images of neural activity at cellular resolution. By imaging much faster and with less harm to brain tissue than traditional two-photon microscopy, the new approach could provide a clearer view of how neurons communicate in real time, leading to new insights into brain function and neurological diseases.

16 Aug 2024

Advancing Genome Visualization with CRISPR/Cas9 Technology in Live Cells

Understanding the spatiotemporal organization of the genome in the nucleus is crucial for advancing our knowledge of chromatin structure and its functional dynamics in both normal and diseased states.

13 Aug 2024