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A gene is a unit of heredity in a living organism. It normally resides on a stretch of DNA that codes for a type of protein or for an RNA chain that has a function in the organism. All living things depend on genes, as they specify all proteins and functional RNA chains.

Meta-scale approach to quantifying the protein variants in the human body

A key conundrum in biology is why many very simple creatures, such as the widely studied worm C. elegans, have almost as many genes as the human genome, which has about 20,000 genes.

27 Mar 2023

Analyzing how the global regulation factor reshapes the cell-fate-decision landscape

Genes and their regulatory relationships form complex networks that govern cell differentiation trajectories. However, predicting and understanding cell fate decisions using bottom-up network topology is still side-lined.

27 Mar 2023

Key gene involved in crop alkaline tolerance discovered

Chinese scientists have identified a key gene involved in crop alkaline tolerance that may greatly improve crop yield in sodic environments through the use of genetic engineering.

24 Mar 2023

New breakthrough in controlling plant responses to temperature

UC Riverside scientists have significantly advanced the race to control plant responses to temperature on a rapidly warming planet.

24 Mar 2023

Innovative new approach to constructing a nose in young patients with arhinia

Congenital arhinia (meaning patients born without a nose) is a rare condition associated with high mortality if not identified.

24 Mar 2023

Walnuts might support heart health by changing the gut microbiome

Scientists at Texas Tech University have revealed that the heart-healthy benefits of eating walnuts could be a result of the changes they induce in the gut microbiome.

24 Mar 2023

RHOJ acts as a key regulator of EMT-associated resistance to chemotherapy

In spite of the ongoing development of new targeted therapies, chemotherapies remain the most popular used treatment for patients with advanced cancers. Chemotherapy resistance is one of the leading causes of cancer treatment failure and death.

23 Mar 2023

Single mechanosensitive protein shown to contribute to fibrosis in multiple organs

Researchers from Kyushu University have found how a single mechanosensitive protein induces the process that thickens and scars tissue, known as fibrosis. The protein, called VGLL3, was shown to contribute to fibrosis in multiple organs.

23 Mar 2023

Variations in methylation linked to age in the human sperm epigenome

A higher risk of reproductive and child health issues is linked to advanced paternal age. Increasing evidence points to age-related alterations in the sperm epigenome as one underlying cause.

23 Mar 2023

Identifying the underlying causes of rare genetic immune disorders

The activated PI3K Delta syndrome 2 (APDS2) is a rare genetic disease that is caused by cellular anomalies, according to experts from the Garvan Institute of Medical Research.

23 Mar 2023

Revealing how hematopoietic stem cells acquire malignant traits in cancer

Scientists from Lund University’s Faculty of Medicine have discovered a novel mechanism connecting ribonucleic acid (RNA) metabolism to the development of leukemia in patients with myelodysplastic syndrome (MDS).

23 Mar 2023

Study identifies 238 amyloid toxicity protective or activator genes

An international study led by the Molecular Physiology Laboratory at the UPF Department of Medicine and Life Sciences (MELIS) identifies new genes that modulate the toxicity of the protein β-amyloid, responsible for causing Alzheimer's disease.

22 Mar 2023

CABBI/GLBRC researchers peer into the complexities of life on a leaf

"Have you ever wondered about life on a leaf?" Great Lakes Bioenergy Research Center (GLBRC) researcher Ashley Shade asks a simple question, but it's one well worth investigation.

22 Mar 2023

Uncovering the evolutionary history of wheat during the Holocene

Over 35% of the world’s population is nourished by wheat, which includes bread wheat and its relatives. Wheat has been cultivated for more than 10,000 years, beginning with the “Neolithic Revolution,” and is one of the earliest ancient crops to emerge in the Fertile Crescent.

21 Mar 2023