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New protocol identifies mismatch repair deficiency

Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in the colon, endometrial, and other cancers.

22 Jan 2021

Study defines the most crucial genes that Increase risk of breast cancer

Genetic inheritance affects the likelihood of developing breast cancer. Some genes are already known to increase cancer risk; other genes are suspected to be involved, but not to what extent. It is crucial to clarify this issue to improve prevention since it opens the way to more personalized follow-up and screening programs.

22 Jan 2021

Immature dendritic cells in young children can induce robust immune responses

A new study performed by scientists from Ludwig-Maximilians-Universitaet Muenchen (LMU) has demonstrated that putatively immature dendritic cells in young children can trigger powerful immune responses. The findings may result in better vaccination protocols.

21 Jan 2021

Venom of Tiger Rattlesnakes may advance genetic science

Among all rattlesnake species, the Tiger Rattlesnake has the simplest yet most lethal venom. Now, a new study performed by a team of researchers can describe the genetics behind the venomous bite of the Tiger Rattlesnake.

21 Jan 2021

Antibiotic resistance may be spreading much faster than expected

Pathogenic bacteria in humans are developing resistance to antibiotics much faster than expected. Now, computational research at Chalmers University of Technology, Sweden, shows that one reason could be significant genetic transfer between bacteria in our ecosystems and to humans. This work has also led to new tools for resistance researchers.

21 Jan 2021

Study reveals genetic variants that increase the risk of nocturnal enuresis

In a large-scale study of Danish children and young people, researchers from Aarhus University have for the first time found genetic variants that increase the risk of nocturnal enuresis - commonly known as bedwetting or nighttime incontinence. The findings provide completely new insights into the processes in the body causing this widespread phenomenon.

20 Jan 2021

New genome resource helps study genetic traits in major crops

Thanks to a new genome resource created for green millet, researchers will be able to study the genetics of crucial traits in crops, like sorghum and maize, in a much better way. The resource was created by three RIKEN scientists.

18 Jan 2021

Study shows how specific gene mutations cause different types of diseases

Renowned cancer experts have resolved a query of how different types of mutations in a single gene are responsible for causing various types of diseases.

15 Jan 2021

Study identifies gene networks that control sugar and organic acid metabolism during fruit development

The watermelon and melon cultivation project by researchers achieved a new advancement in controlling the metabolism of sugar in watermelon fruit.

15 Jan 2021

Researchers make new discovery in the quest for novel antibiotics

Scientists who highlighted the bug-busting properties of bacteria in Northern Irish soil have made another exciting discovery in the quest to discover new antibiotics.

15 Jan 2021

Researchers use heat map data to reverse engineer chromosome models

Genome analysis can provide information on genes and their location on a strand of DNA, but such analysis reveals little about their spatial location in relation to one another within chromosomes -- the highly complex, three-dimensional structures that hold genetic information.

15 Jan 2021

Scientists use gene-editing technique to considerably increase the production of formicamycin antibiotics

Researchers have leveraged gene-editing advances to obtain a 10 times increase in the development of super-bug targeting formicamycin antibiotics.

13 Jan 2021

Scientists identify the sensor in human lungs that detects SARS-CoV-2

Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it's time to mount an antiviral response.

13 Jan 2021

Study reveals richness of space-time gene expression dynamics of the liver

Nothing in biology is static. Biological processes fluctuate over time, and if we are to put together an accurate picture of cells, tissues, organs etc., we have to take into account their temporal patterns. In fact, this effort has given rise to an entire field of study known as "chronobiology".

12 Jan 2021

New discovery helps explain how COVID-19 suppresses the body’s immune response

Seeking to understand why COVID-19 is able to suppress the body's immune response, new research from the USC Leonard Davis School of Gerontology suggests that mitochondria are one of the first lines of defense against COVID-19 and identifies key differences in how SARS-CoV-2, the virus that causes COVID-19, interacts with mitochondrial genes when compared to other viruses.

12 Jan 2021

Sequencing-based solution can help determine patients’ response to infection therapy

Scientists from the University of Helsinki have created a new sequencing-based strategy for identifying pathogens from complex samples.

8 Jan 2021

Proteogenomic study may lead to more effective treatments for head and neck squamous cell carcinoma

Proteogenomic studies may provide a better understanding of how to match cancer patients with an effective treatment for their specific cancer.

8 Jan 2021

Scientists trace back evolutionary history of antibiotic resistance genes

By comparing thousands of bacterial genomes, scientists in Gothenburg, Sweden have traced back the evolutionary history of antibiotic resistance genes. In almost all cases where an origin could be determined, the gene started to spread from bacteria that, themselves, can cause disease.

8 Jan 2021

Study uncovers unusual sex chromosomes of Australian iconic animals

The sex chromosomes genetically define the developmental fate of an embryo to become a male or a female individual, and usually, appear as one pair of morphologically different chromosomes between sexes.

8 Jan 2021

New technique to detect gene doping in human plasma

All athletes wish to be at the top of their game while competing, yet some turn to corrupt strategies to achieve peak speed, agility, and muscle growth. Latest advancements in gene editing technology could lure athletes to change their DNA to gain an upper hand.

7 Jan 2021