Genetic News and Research

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Chemosynthesis fuels ocean microbes in the darkest depths

A world first study reverses the idea that the bulk of life in the ocean is fuelled by photosynthesis via sunshine, revealing that many ocean microbes in fact get their energy from hydrogen and carbon monoxide.

7 Feb 2023

Newly discovered gene signature accurately predicts the functioning of P53 variants

In a paper published in PNAS, Maureen Murphy, Ph.D., Deputy Director of Wistar's Ellen and Ronald Caplan Cancer Center and Ira Brind Professor and Program Leader in the Molecular & Cellular Oncogenesis Program, and team have identified a gene signature that accurately predicts the functioning of P53 variants, important information to assessing cancer risk and optimizing choices for cancer therapeutics.

7 Feb 2023

Researchers decipher genomic mechanisms involved in complex eye disease

Researchers at Tel Aviv University identified a new genetic risk factor for the complex eye disease AMD (Age-related Macular Degeneration), a leading cause for loss of eyesight at an advanced age.

7 Feb 2023

Macrophages as new therapeutic target to address obesity-related diseases

Macrophages are immune system cells that control inflammation and tissue function in addition to being crucial in the early response to microbial infection. Since it aids in the repair of damaged tissue, inflammation is a natural physiological response.

6 Feb 2023

New hexameric structure of the protein triggering antibiotic resistance discovered

All living organisms require DNA replication to ensure the genetic integrity of the following generation. On the other hand, bacteria have the ability to horizontally transfer genetic information to other bacteria.

6 Feb 2023

Researchers use AI to identify genes that are critical to a cancer cell’s survival

Researchers at the University of Sussex are using Artificial Intelligence (AI) technology to analyze different types of cancer cells to understand different gene dependencies, and to identify genes that are critical to a cell's survival.

6 Feb 2023

Experimental optimization of prime editing to achieve high efficiency

Genome editing technologies have enormous potential for treating genetic diseases. Techniques like the extensively used CRISPR/Cas9 gene scissors target the source of the disease directly in the DNA.

3 Feb 2023

Researchers establish and characterize a stable iPSC line for modeling human disease

Bill Skarnes and team established and characterized a stable iPSC line, KOLF2.1J, to act as a high-quality baseline platform for modeling human disease.

3 Feb 2023

RNA-G quadruplexes in living cells: A real-time study

Amyotrophic lateral sclerosis (ALS), sometimes referred to as Stephen Hawking’s disease and Lou Gehrig’s disease is a neurological condition that causes the body’s muscles to gradually lose control.

2 Feb 2023

Easy-to-use method quantifies exosomal miRNAs

Most cancer diagnostic procedures, like endoscopies, biopsies, and mammograms, are stressful and invasive. Although blood samples may be a less unpleasant option, only a few forms of the disease can as of now be diagnosed this way.

2 Feb 2023

Study uncovers a link between the genetic instructions for production and perception of sex pheromones

It's almost Valentine's Day, and love is in the air. Or in the waxy coating on your skin, if you are a vinegar fly. That's where flies encounter pheromones that play an important role in regulating sexual attraction.

1 Feb 2023

Exploring how plants can adapt to accelerating aridity due to climate change

At a time when climate change is making many areas of the planet hotter and drier, it's sobering to think that deserts are relatively new biomes that have grown considerably over the past 30 million years.

1 Feb 2023

Nearly two million-euro ERC Consolidator Grant supports research on fruit fly's locomotion

When we try walking in a straight line with our eyes closed, after a few steps forward we inevitably deviate from our intended path.

1 Feb 2023

Study identifies genetic mutation in the SPTSSA gene as cause of Hereditary Spastic Paraplegia

A genetic mutation in the SPTSSA gene is identified as the cause of Hereditary Spastic Paraplegia, a rare disease that causes progressive weakness, stiffness and spasticity in the lower extremities, according to a study, "SPTSSA variants alter sphingolipid synthesis and cause a complex hereditary spastic paraplegia," published in Brain on on Jan. 30.

1 Feb 2023

Genetic News and Research

Chemosynthesis fuels ocean microbes in the darkest depths

Newly discovered gene signature accurately predicts the functioning of P53 variants

Researchers decipher genomic mechanisms involved in complex eye disease

Macrophages as new therapeutic target to address obesity-related diseases

New hexameric structure of the protein triggering antibiotic resistance discovered

Researchers use AI to identify genes that are critical to a cancer cell’s survival

Experimental optimization of prime editing to achieve high efficiency

Researchers establish and characterize a stable iPSC line for modeling human disease

RNA-G quadruplexes in living cells: A real-time study

Easy-to-use method quantifies exosomal miRNAs

Study uncovers a link between the genetic instructions for production and perception of sex pheromones

Exploring how plants can adapt to accelerating aridity due to climate change

Nearly two million-euro ERC Consolidator Grant supports research on fruit fly's locomotion

Study identifies genetic mutation in the SPTSSA gene as cause of Hereditary Spastic Paraplegia

UNC research describes another layer to the challenge of HIV latency

Research supports the safety and efficacy of COVID-19 vaccination in cancer patients receiving immunotherapy

Cochlear organoids provide a platform to understand sensorineural hearing loss

Analyzing how disease-causing fungi become resistant to antifungal drugs

Tweezers illustrate how chemotherapy affects DNA

Novel, more accurate computational tool for long-read RNA sequencing developed

Genetics & Genomics - Second Edition eBook

Quorum Bio: Where Synthetic Biology Meets Sustainable Farming

Diagnostic Biochips: Pioneering Brain Research Tools for the Future

Commercializing Innovation in a Life Sciences Ecosystem

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